Transmission and decorrelation methods for detecting rare variants using sequencing data from related individuals

por Darst, Burcu F., Engelman, Corinne D.
Publicado 2016

Using recursive feature elimination in random forest to account for correlated variables in high dimensional data

por Darst, Burcu F., Malecki, Kristen C., Engelman, Corinne D.
Publicado 2018

Data mining and machine learning approaches for the integration of genome-wide association and methylation data: methodology and main conclusions from GAW20

por Darst, Burcu, Engelman, Corinne D., Tian, Ye, Lorenzo Bermejo, Justo
Publicado 2018

Prioritization of family member sequencing for the detection of rare variants

por Sippy, Rachel, Kolesar, Jill M, Darst, Burcu F, Engelman, Corinne D
Publicado 2016

Longitudinal plasma metabolomics of aging and sex

por Darst, Burcu F., Koscik, Rebecca L., Hogan, Kirk J., Johnson, Sterling C., Engelman, Corinne D.
Publicado 2019

Carrier frequency estimation of Zellweger spectrum disorder using ExAC database and bioinformatics tools

por Vasiljevic, Eva, Ye, Zhan, Pavelec, Derek M., Darst, Burcu F., Engelman, Corinne D., Baker, Mei W.
Publicado 2019

CSF metabolites associate with CSF tau and improve prediction of Alzheimer's disease status

por Dong, Ruocheng, Darst, Burcu F., Deming, Yuetiva, Ma, Yue, Lu, Qiongshi, Zetterberg, Henrik, Blennow, Kaj, Carlsson, Cynthia M., Johnson, Sterling C., Asthana, Sanjay, Engelman, Corinne D.
Publicado 2021

Including diverse and admixed populations in genetic epidemiology research

por Caliebe, Amke, Tekola‐Ayele, Fasil, Darst, Burcu F., Wang, Xuexia, Song, Yeunjoo E., Gui, Jiang, Sebro, Ronnie A., Balding, David J., Saad, Mohamad, Dubé, Marie‐Pierre
Publicado 2022

The gut microbiota-derived metabolite trimethylamine N-oxide is elevated in Alzheimer’s disease

por Vogt, Nicholas M., Romano, Kymberleigh A., Darst, Burcu F., Engelman, Corinne D., Johnson, Sterling C., Carlsson, Cynthia M., Asthana, Sanjay, Blennow, Kaj, Zetterberg, Henrik, Bendlin, Barbara B., Rey, Federico E.
Publicado 2018

Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations

por Panyard, Daniel J., Kim, Kyeong Mo, Darst, Burcu F., Deming, Yuetiva K., Zhong, Xiaoyuan, Wu, Yuchang, Kang, Hyunseung, Carlsson, Cynthia M., Johnson, Sterling C., Asthana, Sanjay, Engelman, Corinne D., Lu, Qiongshi
Publicado 2021

Macrovascular and microvascular cerebral blood flow in adults at risk for Alzheimer's disease

por Clark, Lindsay R., Berman, Sara E., Rivera-Rivera, Leonardo A., Hoscheidt, Siobhan M., Darst, Burcu F., Engelman, Corinne D., Rowley, Howard A., Carlsson, Cynthia M., Asthana, Sanjay, Turski, Patrick, Wieben, Oliver, Johnson, Sterling C.
Publicado 2017

Association Between a 22-feature Genomic Classifier and Biopsy Gleason Upgrade During Active Surveillance for Prostate Cancer

por Press, Benjamin H., Jones, Tashzna, Olawoyin, Olamide, Lokeshwar, Soum D., Rahman, Syed N., Khajir, Ghazal, Lin, Daniel W., Cooperberg, Matthew R., Loeb, Stacy, Darst, Burcu F., Zheng, Yingye, Chen, Ronald C., Witte, John S., Seibert, Tyler M., Catalona, William J., Leapman, Michael S., Sprenkle, Preston C.
Publicado 2022

A Genome Sequencing Program for Novel Undiagnosed Diseases

por Bloss, Cinnamon S., Scott-Van Zeeland, Ashley A., Topol, Sarah E., Darst, Burcu F., Boeldt, Debra L., Erikson, Galina A., Bethel, Kelly J., Bjork, Robert L., Friedman, Jennifer R., Hwynn, Nelson, Patay, Bradley A., Pockros, Paul J., Scott, Erick R., Simon, Ronald A., Williams, Gary W., Schork, Nicholas J., Topol, Eric J., Torkamani, Ali
Publicado 2015

Genome-wide association study of pancreatic fat: The Multiethnic Cohort Adiposity Phenotype Study

por Streicher, Samantha A., Lim, Unhee, Park, S. Lani, Li, Yuqing, Sheng, Xin, Hom, Victor, Xia, Lucy, Pooler, Loreall, Shepherd, John, Loo, Lenora W. M., Darst, Burcu F., Highland, Heather M., Polfus, Linda M., Bogumil, David, Ernst, Thomas, Buchthal, Steven, Franke, Adrian A., Setiawan, Veronica Wendy, Tiirikainen, Maarit, Wilkens, Lynne R., Haiman, Christopher A., Stram, Daniel O., Cheng, Iona, Le Marchand, Loïc
Publicado 2021

Dyslexia and language impairment associated genetic markers influence cortical thickness and white matter in typically developing children

por Eicher, John D., Montgomery, Angela M., Akshoomoff, Natacha, Amaral, David G., Bloss, Cinnamon S., Libiger, Ondrej, Schork, Nicholas J., Darst, Burcu F., Casey, B. J., Chang, Linda, Ernst, Thomas, Frazier, Jean, Kaufmann, Walter E., Keating, Brian, Kenet, Tal, Kennedy, David, Mostofsky, Stewart, Murray, Sarah S., Sowell, Elizabeth R., Bartsch, Hauke, Kuperman, Joshua M., Brown, Timothy T., Hagler, Donald J., Dale, Anders M., Jernigan, Terry L., Gruen, Jeffrey R.
Publicado 2015

Validation of a multi-ancestry polygenic risk score and age-specific risks of prostate cancer: A meta-analysis within diverse populations

por Chen, Fei, Darst, Burcu F, Madduri, Ravi K, Rodriguez, Alex A, Sheng, Xin, Rentsch, Christopher T, Andrews, Caroline, Tang, Wei, Kibel, Adam S, Plym, Anna, Cho, Kelly, Jalloh, Mohamed, Gueye, Serigne Magueye, Niang, Lamine, Ogunbiyi, Olufemi J, Popoola, Olufemi, Adebiyi, Akindele O, Aisuodionoe-Shadrach, Oseremen I, Ajibola, Hafees O, Jamda, Mustapha A, Oluwole, Olabode P, Nwegbu, Maxwell, Adusei, Ben, Mante, Sunny, Darkwa-Abrahams, Afua, Mensah, James E, Adjei, Andrew Anthony, Diop, Halimatou, Lachance, Joseph, Rebbeck, Timothy R, Ambs, Stefan, Gaziano, J Michael, Justice, Amy C, Conti, David V, Haiman, Christopher A
Publicado 2022

Testing the generalizability of ancestry-specific polygenic risk scores to predict prostate cancer in sub-Saharan Africa

por Kim, Michelle S., Naidoo, Daphne, Hazra, Ujani, Quiver, Melanie H., Chen, Wenlong C., Simonti, Corinne N., Kachambwa, Paidamoyo, Harlemon, Maxine, Agalliu, Ilir, Baichoo, Shakuntala, Fernandez, Pedro, Hsing, Ann W., Jalloh, Mohamed, Gueye, Serigne M., Niang, Lamine, Diop, Halimatou, Ndoye, Medina, Snyper, Nana Yaa, Adusei, Ben, Mensah, James E., Abrahams, Afua O. D., Biritwum, Richard, Adjei, Andrew A., Adebiyi, Akindele O., Shittu, Olayiwola, Ogunbiyi, Olufemi, Adebayo, Sikiru, Aisuodionoe-Shadrach, Oseremen I., Nwegbu, Maxwell M., Ajibola, Hafees O., Oluwole, Olabode P., Jamda, Mustapha A., Singh, Elvira, Pentz, Audrey, Joffe, Maureen, Darst, Burcu F., Conti, David V., Haiman, Christopher A., Spies, Petrus V., van der Merwe, André, Rohan, Thomas E., Jacobson, Judith, Neugut, Alfred I., McBride, Jo, Andrews, Caroline, Petersen, Lindsay N., Rebbeck, Timothy R., Lachance, Joseph
Publicado 2022

Genetic discovery and risk characterization in type 2 diabetes across diverse populations

por Polfus, Linda M., Darst, Burcu F., Highland, Heather, Sheng, Xin, Ng, Maggie C.Y., Below, Jennifer E., Petty, Lauren, Bien, Stephanie, Sim, Xueling, Wang, Wei, Fontanillas, Pierre, Patel, Yesha, Preuss, Michael, Schurmann, Claudia, Du, Zhaohui, Lu, Yingchang, Rhie, Suhn K., Mercader, Joseph M., Tusie-Luna, Teresa, González-Villalpando, Clicerio, Orozco, Lorena, Spracklen, Cassandra N., Cade, Brian E., Jensen, Richard A., Sun, Meng, Joo, Yoonjung Yoonie, An, Ping, Yanek, Lisa R., Bielak, Lawrence F., Tajuddin, Salman, Nicolas, Aude, Chen, Guanjie, Raffield, Laura, Guo, Xiuqing, Chen, Wei-Min, Nadkarni, Girish N., Graff, Mariaelisa, Tao, Ran, Pankow, James S., Daviglus, Martha, Qi, Qibin, Boerwinkle, Eric A., Liu, Simin, Phillips, Lawrence S., Peters, Ulrike, Carlson, Chris, Wikens, Lynne R., Le Marchand, Loic, North, Kari E., Buyske, Steven, Kooperberg, Charles, Loos, Ruth J.F., Stram, Daniel O., Haiman, Christopher A.
Publicado 2021

The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes

por Huerta-Chagoya, Alicia, Schroeder, Philip, Mandla, Ravi, Deutsch, Aaron J., Zhu, Wanying, Petty, Lauren, Yi, Xiaoyan, Cole, Joanne B., Udler, Miriam S., Dornbos, Peter, Porneala, Bianca, DiCorpo, Daniel, Liu, Ching-Ti, Li, Josephine H., Szczerbiński, Lukasz, Kaur, Varinderpal, Kim, Joohyun, Lu, Yingchang, Martin, Alicia, Eizirik, Decio L., Marchetti, Piero, Marselli, Lorella, Chen, Ling, Srinivasan, Shylaja, Todd, Jennifer, Flannick, Jason, Gubitosi-Klug, Rose, Levitsky, Lynne, Shah, Rachana, Kelsey, Megan, Burke, Brian, Dabelea, Dana M., Divers, Jasmin, Marcovina, Santica, Stalbow, Lauren, Loos, Ruth J. F., Darst, Burcu F., Kooperberg, Charles, Raffield, Laura M., Haiman, Christopher, Sun, Quan, McCormick, Joseph B., Fisher-Hoch, Susan P., Ordoñez, Maria L., Meigs, James, Baier, Leslie J., González-Villalpando, Clicerio, González-Villalpando, Maria Elena, Orozco, Lorena, García-García, Lourdes, Moreno-Estrada, Andrés, Aguilar-Salinas, Carlos A., Tusié, Teresa, Dupuis, Josée, Ng, Maggie C. Y., Manning, Alisa, Highland, Heather M., Cnop, Miriam, Hanson, Robert, Below, Jennifer, Florez, Jose C., Leong, Aaron, Mercader, Josep M.
Publicado 2023

Evaluating Approaches for Constructing Polygenic Risk Scores for Prostate Cancer in Men of African and European Ancestry

por Darst, Burcu F., Shen, Jiayi, Madduri, Ravi K., Rodriguez, Alexis A., Xiao, Yukai, Sheng, Xin, Saunders, Edward J., Dadaev, Tokhir, Brook, Mark N., Hoffmann, Thomas J., Muir, Kenneth, Wan, Peggy, Le Marchand, Loic, Wilkens, Lynne, Wang, Ying, Schleutker, Johanna, MacInnis, Robert J., Cybulski, Cezary, Neal, David E., Nordestgaard, Børge G., Nielsen, Sune F., Batra, Jyotsna, Clements, Judith A., Grönberg, Henrik, Pashayan, Nora, Travis, Ruth C., Park, Jong Y., Albanes, Demetrius, Weinstein, Stephanie, Mucci, Lorelei A., Hunter, David J., Penney, Kathryn L., Tangen, Catherine M., Hamilton, Robert J., Parent, Marie-Élise, Stanford, Janet L., Koutros, Stella, Wolk, Alicja, Sørensen, Karina D., Blot, William J., Yeboah, Edward D., Mensah, James E., Lu, Yong-Jie, Schaid, Daniel J., Thibodeau, Stephen N., West, Catharine M., Maier, Christiane, Kibel, Adam S., Cancel-Tassin, Géraldine, Menegaux, Florence, John, Esther M., Grindedal, Eli Marie, Khaw, Kay-Tee, Ingles, Sue A., Vega, Ana, Rosenstein, Barry S., Teixeira, Manuel R., Kogevinas, Manolis, Cannon-Albright, Lisa, Huff, Chad, Multigner, Luc, Kaneva, Radka, Leach, Robin J., Brenner, Hermann, Hsing, Ann W., Kittles, Rick A., Murphy, Adam B., Logothetis, Christopher J., Neuhausen, Susan L., Isaacs, William B., Nemesure, Barbara, Hennis, Anselm J., Carpten, John, Pandha, Hardev, De Ruyck, Kim, Xu, Jianfeng, Razack, Azad, Teo, Soo-Hwang, Newcomb, Lisa F., Fowke, Jay H., Neslund-Dudas, Christine, Rybicki, Benjamin A., Gamulin, Marija, Usmani, Nawaid, Claessens, Frank, GagoDominguez, Manuela, Castelao, Jose Esteban, Townsend, Paul A., Crawford, Dana C., Petrovics, Gyorgy, Casey, Graham, Roobol, Monique J., Hu, Jennifer F., Berndt, Sonja I., Van Den Eeden, Stephen K., Easton, Douglas F., Chanock, Stephen J., Cook, Michael B., Wiklund, Fredrik, Witte, John S., Eeles, Rosalind A., Kote-Jarai, Zsofia, Watya, Stephen, Gaziano, John M., Justice, Amy C., Conti, David V., Haiman, Christopher A.
Publicado 2023