Probing the Peripheral Site of Human Butyrylcholinesterase

por Macdonald, Ian R., Martin, Earl, Rosenberry, Terrone L., Darvesh, Sultan
Publicado 2012

1-(3-Tert-Butylphenyl)-2,2,2-Trifluoroethanone as a Potent Transition-State Analogue Slow-Binding Inhibitor of Human Acetylcholinesterase: Kinetic, MD and QM/MM Studies

por Zueva, Irina V., Lushchekina, Sofya V., Pottie, Ian R., Darvesh, Sultan, Masson, Patrick
Publicado 2020

2-Pyridone natural products as inhibitors of SARS-CoV-2 main protease

por Forrestall, Katrina L., Burley, Darcy E., Cash, Meghan K., Pottie, Ian R., Darvesh, Sultan
Publicado 2021

An integrated proteomics approach shows synaptic plasticity changes in an APP/PS1 Alzheimer's mouse model

por Kempf, Stefan J., Metaxas, Athanasios, Ibáñez-Vea, María, Darvesh, Sultan, Finsen, Bente, Larsen, Martin R.
Publicado 2016

Increased Inflammation and Unchanged Density of Synaptic Vesicle Glycoprotein 2A (SV2A) in the Postmortem Frontal Cortex of Alzheimer’s Disease Patients

por Metaxas, Athanasios, Thygesen, Camilla, Briting, Sanne R. R., Landau, Anne M., Darvesh, Sultan, Finsen, Bente
Publicado 2019

No difference in cerebral perfusion between the wild-type and the 5XFAD mouse model of Alzheimer’s disease

por DeBay, Drew R., Phi, Tân-Trào, Bowen, Chris V., Burrell, Steven C., Darvesh, Sultan
Publicado 2022

Targeting butyrylcholinesterase for preclinical single photon emission computed tomography (SPECT) imaging of Alzheimer's disease

por DeBay, Drew R., Reid, George A., Pottie, Ian R., Martin, Earl, Bowen, Chris V., Darvesh, Sultan
Publicado 2017

Comparison of the Binding of Reversible Inhibitors to Human Butyrylcholinesterase and Acetylcholinesterase: A Crystallographic, Kinetic and Calorimetric Study

por Rosenberry, Terrone L., Brazzolotto, Xavier, Macdonald, Ian R., Wandhammer, Marielle, Trovaslet-Leroy, Marie, Darvesh, Sultan, Nachon, Florian
Publicado 2017

Quantification of Butyrylcholinesterase Activity as a Sensitive and Specific Biomarker of Alzheimer’s Disease

por Macdonald, Ian R., Maxwell, Selena P., Reid, George A., Cash, Meghan K., DeBay, Drew R., Darvesh, Sultan
Publicado 2017

A method for the efficient evaluation of substrate-based cholinesterase imaging probes for Alzheimer’s disease

por Darvesh, Sultan, Banfield, Scott, Dufour, Maeve, Forrestall, Katrina L., Maillet, Hillary, Reid, G. Andrew, Sands, Dane, Pottie, Ian R.
Publicado 2023

Diverse Protein Profiles in CNS Myeloid Cells and CNS Tissue From Lipopolysaccharide- and Vehicle-Injected APP(SWE)/PS1(ΔE9) Transgenic Mice Implicate Cathepsin Z in Alzheimer’s Di...

por Thygesen, Camilla, Ilkjær, Laura, Kempf, Stefan J., Hemdrup, Anne Louise, von Linstow, Christian Ulrich, Babcock, Alicia A., Darvesh, Sultan, Larsen, Martin R., Finsen, Bente
Publicado 2018

Mild Microglial Responses in the Cortex and Perivascular Macrophage Infiltration in Subcortical White Matter in Dogs with Age-Related Dementia Modelling Prodromal Alzheimer’s Disea...

por Thomsen, Barbara Blicher, Madsen, Cecilie, Krohn, Katrine Tækker, Thygesen, Camilla, Schütt, Trine, Metaxas, Athanasios, Darvesh, Sultan, Agerholm, Jørgen Steen, Wirenfeldt, Martin, Berendt, Mette, Finsen, Bente
Publicado 2021

Ageing and amyloidosis underlie the molecular and pathological alterations of tau in a mouse model of familial Alzheimer’s disease

por Metaxas, Athanasios, Thygesen, Camilla, Kempf, Stefan J., Anzalone, Marco, Vaitheeswaran, Ramanan, Petersen, Sussanne, Landau, Anne M., Audrain, Hélène, Teeling, Jessica L., Darvesh, Sultan, Brooks, David J., Larsen, Martin R., Finsen, Bente
Publicado 2019

The Toronto Cognitive Assessment (TorCA): normative data and validation to detect amnestic mild cognitive impairment

por Freedman, Morris, Leach, Larry, Carmela Tartaglia, M., Stokes, Kathryn A., Goldberg, Yael, Spring, Robyn, Nourhaghighi, Nima, Gee, Tom, Strother, Stephen C., Alhaj, Mohammad O., Borrie, Michael, Darvesh, Sultan, Fernandez, Alita, Fischer, Corinne E., Fogarty, Jennifer, Greenberg, Barry D., Gyenes, Michelle, Herrmann, Nathan, Keren, Ron, Kirstein, Josh, Kumar, Sanjeev, Lam, Benjamin, Lena, Suvendrini, McAndrews, Mary Pat, Naglie, Gary, Partridge, Robert, Rajji, Tarek K., Reichmann, William, Uri Wolf, M., Verhoeff, Nicolaas P. L. G., Waserman, Jordana L., Black, Sandra E., Tang-Wai, David F.
Publicado 2018

Correction to: The Toronto cognitive assessment (TorCA): normative data and validation to detect amnestic mild cognitive impairment

por Freedman, Morris, Leach, Larry, Carmela Tartaglia, M., Stokes, Kathryn A., Goldberg, Yael, Spring, Robyn, Nourhaghighi, Nima, Gee, Tom, Strother, Stephen C., Alhaj, Mohammad O., Borrie, Michael, Darvesh, Sultan, Fernandez, Alita, Fischer, Corinne E., Fogarty, Jennifer, Greenberg, Barry D., Gyenes, Michelle, Herrmann, Nathan, Keren, Ron, Kirstein, Josh, Kumar, Sanjeev, Lam, Benjamin, Lena, Suvendrini, McAndrews, Mary Pat, Naglie, Gary, Partridge, Robert, Rajji, Tarek K., Reichmann, William, Uri Wolf, M., Verhoeff, Nicolaas P. L. G., Waserman, Jordana L., Black, Sandra E., Tang-Wai, David F.
Publicado 2018

Alzheimer's disease as an autoimmune disorder of innate immunity endogenously modulated by tryptophan metabolites

por Meier‐Stephenson, Felix S., Meier‐Stephenson, Vanessa C., Carter, Michael D., Meek, Autumn R., Wang, Yanfei, Pan, Luzhe, Chen, Qiangwei, Jacobo, Sheila, Wu, Fan, Lu, Erhu, Simms, Gordon A., Fisher, Laural, McGrath, Alaina J., Fermo, Virgil, Barden, Christopher J., Clair, Harman D.S., Galloway, Todd N., Yadav, Arun, Campágna‐Slater, Valérie, Hadden, Mark, Reed, Mark, Taylor, Marcia, Kelly, Brendan, Diez‐Cecilia, Elena, Kolaj, Igri, Santos, Clarissa, Liyanage, Imindu, Sweeting, Braden, Stafford, Paul, Boudreau, Robert, Reid, G. Andrew, Noyce, Ryan S., Stevens, Leanne, Staniszewski, Agnieszka, Zhang, Hong, Murty, Mamidanna R. V. S., Lemaire, Pascale, Chardonnet, Solenne, Richardson, Christopher D., Gabelica, Valérie, DePauw, Edwin, Brown, Richard, Darvesh, Sultan, Arancio, Ottavio, Weaver, Donald F.
Publicado 2022