Regulation of Maximal Open Probability Is a Separable Function of Ca(v)β Subunit in L-type Ca(2+) Channel, Dependent on NH(2) Terminus of α(1C) (Ca(v)1.2α)

por Kanevsky, Nataly, Dascal, Nathan
Publicado 2006

Positive and Negative Coupling of the Metabotropic Glutamate Receptors to a G Protein–activated K(+) Channel, GIRK, in Xenopus Oocytes

por Sharon, Dahlia, Vorobiov, Dmitry, Dascal, Nathan
Publicado 1997

Mutual action by Gγ and Gβ for optimal activation of GIRK channels in a channel subunit-specific manner

por Tabak, Galit, Keren-Raifman, Tal, Kahanovitch, Uri, Dascal, Nathan
Publicado 2019

Molecular basis of the facilitation of the heterooligomeric GIRK1/GIRK4 complex by cAMP dependent protein kinase

por Treiber, Fritz, Rosker, Christian, Keren-Raifman, Tal, Steinecker, Bibiane, Gorischek, Astrid, Dascal, Nathan, Schreibmayer, Wolfgang
Publicado 2013

A Collision Coupling Model Governs the Activation of Neuronal GIRK1/2 Channels by Muscarinic-2 Receptors

por Berlin, Shai, Artzy, Etay, Handklo-Jamal, Reem, Kahanovitch, Uri, Parnas, Hanna, Dascal, Nathan, Yakubovich, Daniel
Publicado 2020

Anion-Sensitive Regions of L-Type CaV1.2 Calcium Channels Expressed in HEK293 Cells

por Babai, Norbert, Kanevsky, Nataly, Dascal, Nathan, Rozanski, George J., Singh, Dhirendra P., Fatma, Nigar, Thoreson, Wallace B.
Publicado 2010

Heterologous Facilitation of G Protein-Activated K(+) Channels by β-Adrenergic Stimulation via Camp-Dependent Protein Kinase

por Müllner, Carmen, Vorobiov, Dimitry, Bera, Amal Kanti, Uezono, Yasuhito, Yakubovich, Daniel, Frohnwieser-Steinecker, Bibiane, Dascal, Nathan, Schreibmayer, Wolfgang
Publicado 2000

A Quantitative Model of the GIRK1/2 Channel Reveals That Its Basal and Evoked Activities Are Controlled by Unequal Stoichiometry of Gα and Gβγ

por Yakubovich, Daniel, Berlin, Shai, Kahanovitch, Uri, Rubinstein, Moran, Farhy-Tselnicker, Isabella, Styr, Boaz, Keren-Raifman, Tal, Dessauer, Carmen W., Dascal, Nathan
Publicado 2015

Andersen–Tawil Syndrome Is Associated With Impaired PIP(2) Regulation of the Potassium Channel Kir2.1

por Handklo-Jamal, Reem, Meisel, Eshcar, Yakubovich, Daniel, Vysochek, Leonid, Beinart, Roy, Glikson, Michael, McMullen, Julie R., Dascal, Nathan, Nof, Eyal, Oz, Shimrit
Publicado 2020

A selectivity filter mutation provides insights into gating regulation of a K(+) channel

por Friesacher, Theres, Reddy, Haritha P., Bernsteiner, Harald, Carlo Combista, J., Shalomov, Boris, Bera, Amal K., Zangerl-Plessl, Eva-Maria, Dascal, Nathan, Stary-Weinzinger, Anna
Publicado 2022

A novel small-molecule selective activator of homomeric GIRK4 channels

por Cui, Meng, Xu, Keman, Gada, Kirin D., Shalomov, Boris, Ban, Michelle, Eptaminitaki, Giasemi C., Kawano, Takeharu, Plant, Leigh D., Dascal, Nathan, Logothetis, Diomedes E.
Publicado 2022

Encephalopathy-causing mutations in Gβ(1) (GNB1) alter regulation of neuronal GIRK channels

por Reddy, Haritha P., Yakubovich, Daniel, Keren-Raifman, Tal, Tabak, Galit, Tsemakhovich, Vladimir A., Pedersen, Maria H., Shalomov, Boris, Colombo, Sophie, Goldstein, David B., Javitch, Jonathan A., Bera, Amal K., Dascal, Nathan
Publicado 2021

Epilepsy in a mouse model of GNB1 encephalopathy arises from altered potassium (GIRK) channel signaling and is alleviated by a GIRK inhibitor

por Colombo, Sophie, Reddy, Haritha P., Petri, Sabrina, Williams, Damian J., Shalomov, Boris, Dhindsa, Ryan S., Gelfman, Sahar, Krizay, Daniel, Bera, Amal K., Yang, Mu, Peng, Yueqing, Makinson, Christopher D., Boland, Michael J., Frankel, Wayne N., Goldstein, David B., Dascal, Nathan
Publicado 2023