Digital Droplet PCR for the Absolute Quantification of Exon Skipping Induced by Antisense Oligonucleotides in (Pre-)Clinical Development for Duchenne Muscular Dystrophy

por Verheul, Ruurd C., van Deutekom, Judith C. T., Datson, Nicole A.
Publicado 2016

Epigenetic mechanisms in migraine: a promising avenue?

por Eising, Else, A Datson, Nicole, van den Maagdenberg, Arn MJM, Ferrari, Michel D
Publicado 2013

Glucocorticoid Receptor and Myocyte Enhancer Factor 2 Cooperate to Regulate the Expression of c-JUN in a Neuronal Context

por Speksnijder, Niels, Christensen, Kenneth V., Didriksen, Michael, De Kloet, E. Ronald, Datson, Nicole A.
Publicado 2012

Use of capillary Western immunoassay (Wes) for quantification of dystrophin levels in skeletal muscle of healthy controls and individuals with Becker and Duchenne muscular dystroph...

por Beekman, Chantal, Janson, Anneke A., Baghat, Aabed, van Deutekom, Judith C., Datson, Nicole A.
Publicado 2018

Paired Hormone Response Elements Predict Caveolin-1 as a Glucocorticoid Target Gene

por van Batenburg, Marinus F., Li, Hualing, Polman, J. Annelies, Lachize, Servane, Datson, Nicole A., Bussemaker, Harmen J., Meijer, Onno C.
Publicado 2010

A genome-wide signature of glucocorticoid receptor binding in neuronal PC12 cells

por Polman, J Annelies E, Welten, Jennifer E, Bosch, Danny S, de Jonge, Robert T, Balog, Judit, van der Maarel, Silvère M, de Kloet, E Ronald, Datson, Nicole A
Publicado 2012

The expanded CAG repeat in the huntingtin gene as target for therapeutic RNA modulation throughout the HD mouse brain

por Datson, Nicole A., González-Barriga, Anchel, Kourkouta, Eleni, Weij, Rudie, van de Giessen, Jeroen, Mulders, Susan, Kontkanen, Outi, Heikkinen, Taneli, Lehtimäki, Kimmo, van Deutekom, Judith C. T.
Publicado 2017

Suppression of Mutant Protein Expression in SCA3 and SCA1 Mice Using a CAG Repeat-Targeting Antisense Oligonucleotide

por Kourkouta, Eleni, Weij, Rudie, González-Barriga, Anchel, Mulder, Melissa, Verheul, Ruurd, Bosgra, Sieto, Groenendaal, Bas, Puoliväli, Jukka, Toivanen, Jussi, van Deutekom, Judith C.T., Datson, Nicole A.
Publicado 2019

Using a State-of-the-Art Toolbox to Evaluate Molecular and Functional Readouts of Antisense Oligonucleotide-Induced Exon Skipping in mdx Mice

por Datson, Nicole A., Bijl, Suzanne, Janson, Anneke, Testerink, Janwillem, van den Eijnde, Rani, Weij, Rudie, Puoliväli, Jukka, Lehtimäki, Kimmo, Bragge, Timo, Ahtoniemi, Toni, van Deutekom, Judith C.
Publicado 2020

A molecular signature of epithelial host defense: comparative gene expression analysis of cultured bronchial epithelial cells and keratinocytes

por Vos, Joost B, Datson, Nicole A, van Kampen, Antoine H, Luyf, Angela C, Verhoosel, Renate M, Zeeuwen, Patrick L, Olthuis, Diana, Rabe, Klaus F, Schalkwijk, Joost, Hiemstra, Pieter S
Publicado 2006

Antisense-mediated isoform switching of steroid receptor coactivator-1 in the central nucleus of the amygdala of the mouse brain

por Zalachoras, Ioannis, Grootaers, Gwendolynn, van Weert, Lisa TCM, Aubert, Yves, de Kreij, Suzanne R, Datson, Nicole A, van Roon-Mom, Willeke MC, Aartsma-Rus, Annemieke, Meijer, Onno C
Publicado 2013

Development of the first marmoset-specific DNA microarray (EUMAMA): a new genetic tool for large-scale expression profiling in a non-human primate

por Datson, Nicole A, Morsink, Maarten C, Atanasova, Srebrena, Armstrong, Victor W, Zischler, Hans, Schlumbohm, Christina, Dutilh, Bas E, Huynen, Martijn A, Waegele, Brigitte, Ruepp, Andreas, de Kloet, E Ronald, Fuchs, Eberhard
Publicado 2007

Detailed genetic and functional analysis of the hDMDdel52/mdx mouse model

por Yavas, Alper, Weij, Rudie, van Putten, Maaike, Kourkouta, Eleni, Beekman, Chantal, Puoliväli, Jukka, Bragge, Timo, Ahtoniemi, Toni, Knijnenburg, Jeroen, Hoogenboom, Marlies Elisabeth, Ariyurek, Yavuz, Aartsma-Rus, Annemieke, van Deutekom, Judith, Datson, Nicole
Publicado 2020

Hippocampal CA1 region shows differential regulation of gene expression in mice displaying extremes in behavioral sensitization to amphetamine: relevance for psychosis susceptibili...

por Datson, Nicole A., Speksnijder, Niels, de Jong, Inge E. M., Steenbergen, Peter J., Vielsted Christensen, Kenneth, Potempa, Krzysztof, Torleif Pedersen, Jan, Egebjerg, Jan, Kallunki, Pekka, Nielsen, Erik B., de Kloet, E. Ronald, Didriksen, Michael
Publicado 2011

Report of a TREAT-NMD/World Duchenne Organisation Meeting on Dystrophin Quantification Methodology

por Aartsma-Rus, Annemieke, Morgan, Jennifer, Lonkar, Pallavi, Neubert, Hendrik, Owens, Jane, Binks, Michael, Montolio, Marisol, Phadke, Rahul, Datson, Nicole, Van Deutekom, Judith, Morris, Glenn E., Rao, V. Ashutosh, Hoffman, Eric P., Muntoni, Francesco, Arechavala-Gomeza, Virginia
Publicado 2019

Intracellular Distribution and Nuclear Activity of Antisense Oligonucleotides After Unassisted Uptake in Myoblasts and Differentiated Myotubes In Vitro

por González-Barriga, Anchel, Nillessen, Bram, Kranzen, Julia, van Kessel, Ingeborg D.G., Croes, Huib J.E., Aguilera, Begoña, de Visser, Peter C., Datson, Nicole A., Mulders, Susan A.M., van Deutekom, Judith C.T., Wieringa, Bé, Wansink, Derick G.
Publicado 2017

A multicenter comparison of quantification methods for antisense oligonucleotide-induced DMD exon 51 skipping in Duchenne muscular dystrophy cell cultures

por Hiller, Monika, Falzarano, Maria Sofia, Garcia-Jimenez, Iker, Sardone, Valentina, Verheul, Ruurd C., Popplewell, Linda, Anthony, Karen, Ruiz-Del-Yerro, Estibaliz, Osman, Hana, Goeman, Jelle J., Mamchaoui, Kamel, Dickson, George, Ferlini, Alessandra, Muntoni, Francesco, Aartsma-Rus, Annemieke, Arechavala-Gomeza, Virginia, Datson, Nicole A., Spitali, Pietro
Publicado 2018

Next Generation Exon 51 Skipping Antisense Oligonucleotides for Duchenne Muscular Dystrophy

por van Deutekom, Judith, Beekman, Chantal, Bijl, Suzanne, Bosgra, Sieto, van den Eijnde, Rani, Franken, Dennis, Groenendaal, Bas, Harquouli, Bouchra, Janson, Anneke, Koevoets, Paul, Mulder, Melissa, Muilwijk, Daan, Peterburgska, Galyna, Querido, Bianca, Testerink, Janwillem, Verheul, Ruurd, de Visser, Peter, Weij, Rudie, Aartsma-Rus, Annemieke, Puoliväli, Jukka, Bragge, Timo, O'Neill, Charles, Datson, Nicole A.
Publicado 2023