Comparative proteome analysis in an Escherichia coli CyDisCo strain identifies stress responses related to protein production, oxidative stress and accumulation of misfolded protei...

por Guerrero Montero, Isabel, Dolata, Katarzyna Magdalena, Schlüter, Rabea, Malherbe, Gilles, Sievers, Susanne, Zühlke, Daniela, Sura, Thomas, Dave, Emma, Riedel, Katharina, Robinson, Colin
Publicado 2019

Extending the half-life of a fab fragment through generation of a humanized anti-human serum albumin Fv domain: An investigation into the correlation between affinity and serum hal...

por Adams, Ralph, Griffin, Laura, Compson, Joanne E., Jairaj, Mark, Baker, Terry, Ceska, Tom, West, Shauna, Zaccheo, Oliver, Davé, Emma, Lawson, Alastair DG., Humphreys, David P., Heywood, Sam
Publicado 2016

Escherichia coli “TatExpress” strains export several g/L human growth hormone to the periplasm by the Tat pathway

por Guerrero Montero, Isabel, Richards, Kirsty L., Jawara, Chillel, Browning, Douglas F., Peswani, Amber R., Labrit, Mickael, Allen, Matthew, Aubry, Cedric, Davé, Emma, Humphreys, David P., Busby, Stephen J. W., Robinson, Colin
Publicado 2019

TRYBE®: an Fc-free antibody format with three monovalent targeting arms engineered for long in vivo half-life

por Davé, Emma, Durrant, Oliver, Dhami, Neha, Compson, Joanne, Broadbridge, Janice, Archer, Sophie, Maroof, Asher, Whale, Kevin, Menochet, Karelle, Bonnaillie, Pierre, Barry, Emily, Wild, Gavin, Peerboom, Claude, Bhatta, Pallavi, Ellis, Mark, Hinchliffe, Matthew, Humphreys, David P., Heywood, Sam P.
Publicado 2023

Fab-dsFv: A bispecific antibody format with extended serum half-life through albumin binding

por Davé, Emma, Adams, Ralph, Zaccheo, Oliver, Carrington, Bruce, Compson, Joanne E., Dugdale, Sarah, Airey, Michael, Malcolm, Sarah, Hailu, Hanna, Wild, Gavin, Turner, Alison, Heads, James, Sarkar, Kaushik, Ventom, Andrew, Marshall, Diane, Jairaj, Mark, Kopotsha, Tim, Christodoulou, Louis, Zamacona, Miren, Lawson, Alastair D., Heywood, Sam, Humphreys, David P.
Publicado 2016