Endothelin Receptors and Their Antagonists()()

por Maguire, Janet J., Davenport, Anthony P.
Publicado 2015

International Union of Basic and Clinical Pharmacology CIII: Chemerin Receptors CMKLR1 (Chemerin(1)) and GPR1 (Chemerin(2)) Nomenclature, Pharmacology, and Function

por Kennedy, Amanda J., Davenport, Anthony P.
Publicado 2018

Apelin, Elabela/Toddler, and biased agonists as novel therapeutic agents in the cardiovascular system

por Yang, Peiran, Maguire, Janet J., Davenport, Anthony P.
Publicado 2015

Editorial: Recent Advances in G Protein-Coupled Receptor Signalling: Impact of Intracellular Location, Environment and Biased Agonism

por Halls, Michelle L., Davenport, Anthony P., Summers, Roger J.
Publicado 2021

Genes encoding ACE2, TMPRSS2 and related proteins mediating SARS-CoV-2 viral entry are upregulated with age in human cardiomyocytes

por Robinson, Emma L., Alkass, Kanar, Bergmann, Olaf, Maguire, Janet J., Roderick, H. Llewelyn, Davenport, Anthony P.
Publicado 2020

The therapeutic potential of apelin in kidney disease

por Chapman, Fiona A., Nyimanu, Duuamene, Maguire, Janet J., Davenport, Anthony P., Newby, David E., Dhaun, Neeraj
Publicado 2021

Trans-myocardial Extraction of Endothelin-1 Correlates with Increased Microcirculatory Resistance following Percutaneous Coronary Intervention

por Abraham, George R., Nyimanu, Duuamene, Kuc, Rhoda E., Maguire, Janet J., Davenport, Anthony P., Hoole, Stephen P.
Publicado 2022

The CCR5 chemokine receptor mediates vasoconstriction and stimulates intimal hyperplasia in human vessels in vitro

por Maguire, Janet J., Jones, Katie L., Kuc, Rhoda E., Clarke, Murray C.H., Bennett, Martin R., Davenport, Anthony P.
Publicado 2014

Expanding the apelin receptor pharmacological toolbox using novel fluorescent ligands

por Williams, Thomas L., Macrae, Robyn G. C., Kuc, Rhoda E., Brown, Alastair J. H., Maguire, Janet J., Davenport, Anthony P.
Publicado 2023

Modulation of endothelin receptors in the failing right ventricle of the heart and vasculature of the lung in human pulmonary arterial hypertension

por Kuc, Rhoda E., Carlebur, Myrna, Maguire, Janet J., Yang, Peiran, Long, Lu, Toshner, Mark, Morrell, Nicholas W., Davenport, Anthony P.
Publicado 2014

The Prodomain-bound Form of Bone Morphogenetic Protein 10 Is Biologically Active on Endothelial Cells

por Jiang, He, Salmon, Richard M., Upton, Paul D., Wei, Zhenquan, Lawera, Aleksandra, Davenport, Anthony P., Morrell, Nicholas W., Li, Wei
Publicado 2016

Apelin-36-[L28A] and Apelin-36-[L28C(30kDa-PEG)] peptides that improve diet induced obesity are G protein biased ligands at the apelin receptor

por Nyimanu, Duuamene, Kuc, Rhoda E., Williams, Thomas L., Bednarek, Maria, Ambery, Philip, Jermutus, Lutz, Maguire, Janet J., Davenport, Anthony P.
Publicado 2019

In vitro metabolism of synthetic Elabela/Toddler (ELA-32) peptide in human plasma and kidney homogenates analyzed with mass spectrometry and validation of endogenous peptide quanti...

por Nyimanu, Duuamene, Kay, Richard G., Kuc, Rhoda E., Brown, Alastair J.H., Gribble, Fiona M., Maguire, Janet J., Davenport, Anthony P.
Publicado 2021

Cardiac action of the first G protein biased small molecule apelin agonist

por Read, Cai, Fitzpatrick, Christopher M., Yang, Peiran, Kuc, Rhoda E., Maguire, Janet J., Glen, Robert C., Foster, Richard E., Davenport, Anthony P.
Publicado 2016

Inotropic Action of the Puberty Hormone Kisspeptin in Rat, Mouse and Human: Cardiovascular Distribution and Characteristics of the Kisspeptin Receptor

por Maguire, Janet J., Kirby, Helen R., Mead, Emma J., Kuc, Rhoda E., d'Anglemont de Tassigny, Xavier, Colledge, William H., Davenport, Anthony P.
Publicado 2011

Plasma levels of apelin are reduced in patients with liver fibrosis and cirrhosis but are not correlated with circulating levels of bone morphogenetic protein 9 and 10

por Owen, Nicola E., Nyimanu, Duuamene, Kuc, Rhoda E., Upton, Paul D., Morrell, Nicholas W., Alexander, Graeme J., Maguire, Janet J., Davenport, Anthony P.
Publicado 2021

Endothelin

por Davenport, Anthony P., Hyndman, Kelly A., Dhaun, Neeraj, Southan, Christopher, Kohan, Donald E., Pollock, Jennifer S., Pollock, David M., Webb, David J., Maguire, Janet J.
Publicado 2016

Reduced circulating BMP10 and BMP9 and elevated endoglin are associated with disease severity, decompensation and pulmonary vascular syndromes in patients with cirrhosis

por Owen, Nicola E., Alexander, Graeme J., Sen, Sambit, Bunclark, Katherine, Polwarth, Gary, Pepke-Zaba, Joanna, Davenport, Anthony P., Morrell, Nicholas, W., Upton, Paul. D.
Publicado 2020

Mechanistic study of the effect of Endothelin SNPs in microvascular angina – Protocol of the PRIZE Endothelin Sub-Study

por Abraham, George R., Morrow, Andrew J., Oliveira, Joana, Weir-McCall, Jonathan R., Davenport, Emma E., Berry, Colin, Davenport, Anthony P., Hoole, Stephen P.
Publicado 2022

Design, Characterization, and First-In-Human Study of the Vascular Actions of a Novel Biased Apelin Receptor Agonist

por Brame, Aimee L., Maguire, Janet J., Yang, Peiran, Dyson, Alex, Torella, Rubben, Cheriyan, Joseph, Singer, Mervyn, Glen, Robert C., Wilkinson, Ian B., Davenport, Anthony P.
Publicado 2015