Cytolytic granules supply Ca(2+) for their own exocytosis via NAADP and resident two-pore channels

por Davis, Lianne C., Galione, Antony
Publicado 2013

Revealing the secrets of secretion

por Galione, Antony, Davis, Lianne C
Publicado 2018

NAADP‐regulated two‐pore channels drive phagocytosis through endo‐lysosomal Ca(2+) nanodomains, calcineurin and dynamin

por Davis, Lianne C, Morgan, Anthony J, Galione, Antony
Publicado 2020

Two-pore channels: going with the flows

por Morgan, Anthony J., Martucci, Lora L., Davis, Lianne C., Galione, Antony
Publicado 2022

Bidirectional Ca(2+) signaling occurs between the endoplasmic reticulum and acidic organelles

por Morgan, Anthony J., Davis, Lianne C., Wagner, Siegfried K.T.Y., Lewis, Alexander M., Parrington, John, Churchill, Grant C., Galione, Antony
Publicado 2013

TPC1 Has Two Variant Isoforms, and Their Removal Has Different Effects on Endo-Lysosomal Functions Compared to Loss of TPC2

por Ruas, Margarida, Chuang, Kai-Ting, Davis, Lianne C., Al-Douri, Areej, Tynan, Patricia W., Tunn, Ruth, Teboul, Lydia, Galione, Antony, Parrington, John
Publicado 2014

Ca(2+) Signaling Occurs via Second Messenger Release from Intraorganelle Synthesis Sites

por Davis, Lianne C., Morgan, Anthony J., Ruas, Margarida, Wong, Julian L., Graeff, Richard M., Poustka, Albert J., Lee, Hon Cheung, Wessel, Gary M., Parrington, John, Galione, Antony
Publicado 2008

NAADP Activates Two-Pore Channels on T Cell Cytolytic Granules to Stimulate Exocytosis and Killing

por Davis, Lianne C., Morgan, Anthony J., Chen, Ji-Li, Snead, Charlotte M., Bloor-Young, Duncan, Shenderov, Eugene, Stanton-Humphreys, Megan N., Conway, Stuart J., Churchill, Grant C., Parrington, John, Cerundolo, Vincenzo, Galione, Antony
Publicado 2012

Mechanistic convergence and shared therapeutic targets in Niemann‐Pick disease

por Colaco, Alexandria, Kaya, Ecem, Adriaenssens, Elias, Davis, Lianne C., Zampieri, Stefania, Fernández‐Suárez, María E., Tan, Chong Y., Deegan, Patrick B., Porter, Forbes D., Galione, Antony, Bembi, Bruno, Dardis, Andrea, Platt, Frances M.
Publicado 2019

Expression of Ca(2+)-permeable two-pore channels rescues NAADP signalling in TPC-deficient cells

por Ruas, Margarida, Davis, Lianne C, Chen, Cheng-Chang, Morgan, Anthony J, Chuang, Kai-Ting, Walseth, Timothy F, Grimm, Christian, Garnham, Clive, Powell, Trevor, Platt, Nick, Platt, Frances M, Biel, Martin, Wahl-Schott, Christian, Parrington, John, Galione, Antony
Publicado 2015

Defective platelet function in Niemann‐Pick disease type C1

por Chen, Oscar C. W., Colaco, Alexandria, Davis, Lianne C., Kiskin, Fedir N., Farhat, Nicole Y., Speak, Anneliese O., Smith, David A., Morris, Lauren, Eden, Emily, Tynan, Patricia, Churchill, Grant C., Galione, Antony, Porter, Forbes D., Platt, Frances M.
Publicado 2020

Purified TPC Isoforms Form NAADP Receptors with Distinct Roles for Ca(2+) Signaling and Endolysosomal Trafficking

por Ruas, Margarida, Rietdorf, Katja, Arredouani, Abdelilah, Davis, Lianne C., Lloyd-Evans, Emyr, Koegel, Heidi, Funnell, Timothy M., Morgan, Anthony J., Ward, John A., Watanabe, Keiko, Cheng, Xiaotong, Churchill, Grant C., Zhu, Michael X., Platt, Frances M., Wessel, Gary M., Parrington, John, Galione, Antony
Publicado 2010

Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick Type C disease cellular pathway

por Fineran, Paul, Lloyd-Evans, Emyr, Lack, Nathan A., Platt, Nick, Davis, Lianne C., Morgan, Anthony J., Höglinger, Doris, Tatituri, Raju Venkata V., Clark, Simon, Williams, Ian M., Tynan, Patricia, Al Eisa, Nada, Nazarova, Evgeniya, Williams, Ann, Galione, Antony, Ory, Daniel S., Besra, Gurdyal S., Russell, David G., Brenner, Michael B., Sim, Edith, Platt, Frances M.
Publicado 2017