Using Cardiovascular Cells from Human Pluripotent Stem Cells for COVID-19 Research: Why the Heart Fails

por Yiangou, Loukia, Davis, Richard P., Mummery, Christine L.
Publicado 2020

Inherited cardiac diseases, pluripotent stem cells, and genome editing combined—the past, present, and future

por van den Brink, Lettine, Grandela, Catarina, Mummery, Christine L., Davis, Richard P.
Publicado 2019

Human pluripotent stem cell models of cardiac disease: from mechanisms to therapies

por Brandão, Karina O., Tabel, Viola A., Atsma, Douwe E., Mummery, Christine L., Davis, Richard P.
Publicado 2017

Beneficial effects of chronic mexiletine treatment in a human model of SCN5A overlap syndrome

por Nasilli, Giovanna, Yiangou, Loukia, Palandri, Chiara, Cerbai, Elisabetta, Davis, Richard P, Verkerk, Arie O, Casini, Simona, Remme, Carol Ann
Publicado 2023

WNT3A Promotes Hematopoietic or Mesenchymal Differentiation from hESCs Depending on the Time of Exposure

por Gertow, Karin, Hirst, Claire E., Yu, Qing C., Ng, Elizabeth S., Pereira, Lloyd A., Davis, Richard P., Stanley, Edouard G., Elefanty, Andrew G.
Publicado 2013

Simultaneous measurement of excitation-contraction coupling parameters identifies mechanisms underlying contractile responses of hiPSC-derived cardiomyocytes

por van Meer, Berend J., Krotenberg, Ana, Sala, Luca, Davis, Richard P., Eschenhagen, Thomas, Denning, Chris, Tertoolen, Leon G. J., Mummery, Christine L.
Publicado 2019

Cryopreservation of human pluripotent stem cell-derived cardiomyocytes is not detrimental to their molecular and functional properties

por van den Brink, Lettine, Brandão, Karina O., Yiangou, Loukia, Mol, Mervyn P.H., Grandela, Catarina, Mummery, Christine L., Verkerk, Arie O., Davis, Richard P.
Publicado 2020

The Linkage Phase of the Polymorphism KCNH2-K897T Influences the Electrophysiological Phenotype in hiPSC Models of LQT2

por van den Brink, Lettine, Brandão, Karina O., Yiangou, Loukia, Blanch-Asensio, Albert, Mol, Mervyn P. H., Mummery, Christine L., Verkerk, Arie O., Davis, Richard P.
Publicado 2021

A COUP-TFII Human Embryonic Stem Cell Reporter Line to Identify and Select Atrial Cardiomyocytes

por Schwach, Verena, Verkerk, Arie O., Mol, Mervyn, Monshouwer-Kloots, Jantine J., Devalla, Harsha D., Orlova, Valeria V., Anastassiadis, Konstantinos, Mummery, Christine L., Davis, Richard P., Passier, Robert
Publicado 2017

Optogenetic Reporters Delivered as mRNA Facilitate Repeatable Action Potential and Calcium Handling Assessment in Human iPSC-Derived Cardiomyocytes

por Yiangou, Loukia, Blanch-Asensio, Albert, de Korte, Tessa, Miller, Duncan C, van Meer, Berend J, Mol, Mervyn P H, van den Brink, Lettine, Brandão, Karina O, Mummery, Christine L, Davis, Richard P
Publicado 2022

STRAIGHT-IN enables high-throughput targeting of large DNA payloads in human pluripotent stem cells

por Blanch-Asensio, Albert, Grandela, Catarina, Brandão, Karina O., de Korte, Tessa, Mei, Hailiang, Ariyurek, Yavuz, Yiangou, Loukia, Mol, Mervyn P.H., van Meer, Berend J., Kloet, Susan L., Mummery, Christine L., Davis, Richard P.
Publicado 2022

Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long-QT syndrome

por Bellin, Milena, Casini, Simona, Davis, Richard P, D'Aniello, Cristina, Haas, Jessica, Ward-van Oostwaard, Dorien, Tertoolen, Leon G J, Jung, Christian B, Elliott, David A, Welling, Andrea, Laugwitz, Karl-Ludwig, Moretti, Alessandra, Mummery, Christine L
Publicado 2013

Contractile Defect Caused by Mutation in MYBPC3 Revealed under Conditions Optimized for Human PSC-Cardiomyocyte Function

por Birket, Matthew J., Ribeiro, Marcelo C., Kosmidis, Georgios, Ward, Dorien, Leitoguinho, Ana Rita, van de Pol, Vera, Dambrot, Cheryl, Devalla, Harsha D., Davis, Richard P., Mastroberardino, Pier G., Atsma, Douwe E., Passier, Robert, Mummery, Christine L.
Publicado 2015

Differential effects on out-of-hospital cardiac arrest of dihydropyridines: real-world data from population-based cohorts across two European countries

por Eroglu, Talip E, Mohr, Grimur H, Blom, Marieke T, Verkerk, Arie O, Souverein, Patrick C, Torp-Pedersen, Christian, Folke, Fredrik, Wissenberg, Mads, van den Brink, Lettine, Davis, Richard P, de Boer, Anthonius, Gislason, Gunnar H, Tan, Hanno L
Publicado 2019

Leadership Training in Endocrinology Fellowship? A Survey of Program Directors and Recent Graduates

por True, Mark W., Folaron, Irene, Wardian, Jana L., Colburn, Jeffrey A., Sauerwein, Tom J., Beckman, Darrick J., Kluesner, Joseph K., Tate, Joshua M., Graybill, Sky D., Davis, Richard P., Paulus, Andrew O., Carlsen, David R., Lewi, Jack E.
Publicado 2017

Isogenic Sets of hiPSC-CMs Harboring Distinct KCNH2 Mutations Differ Functionally and in Susceptibility to Drug-Induced Arrhythmias

por Brandão, Karina O., van den Brink, Lettine, Miller, Duncan C., Grandela, Catarina, van Meer, Berend J., Mol, Mervyn P.H., de Korte, Tessa, Tertoolen, Leon G.J., Mummery, Christine L., Sala, Luca, Verkerk, Arie O., Davis, Richard P.
Publicado 2020

BMP-SMAD Signaling Regulates Lineage Priming, but Is Dispensable for Self-Renewal in Mouse Embryonic Stem Cells

por Gomes Fernandes, Maria, Dries, Ruben, Roost, Matthias S., Semrau, Stefan, de Melo Bernardo, Ana, Davis, Richard P., Ramakrishnan, Ramprasad, Szuhai, Karoly, Maas, Elke, Umans, Lieve, Abon Escalona, Vanesa, Salvatori, Daniela, Deforce, Dieter, Van Criekinge, Wim, Huylebroeck, Danny, Mummery, Christine, Zwijsen, An, Chuva de Sousa Lopes, Susana M.
Publicado 2015

MUSCLEMOTION: A Versatile Open Software Tool to Quantify Cardiomyocyte and Cardiac Muscle Contraction In Vitro and In Vivo

por Sala, Luca, van Meer, Berend J., Tertoolen, Leon G.J., Bakkers, Jeroen, Bellin, Milena, Davis, Richard P., Denning, Chris, Dieben, Michel A.E., Eschenhagen, Thomas, Giacomelli, Elisa, Grandela, Catarina, Hansen, Arne, Holman, Eduard R., Jongbloed, Monique R.M., Kamel, Sarah M., Koopman, Charlotte D., Lachaud, Quentin, Mannhardt, Ingra, Mol, Mervyn P.H., Mosqueira, Diogo, Orlova, Valeria V., Passier, Robert, Ribeiro, Marcelo C., Saleem, Umber, Smith, Godfrey L., Burton, Francis L., Mummery, Christine L.
Publicado 2018

NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network

por Anderson, David J., Kaplan, David I., Bell, Katrina M., Koutsis, Katerina, Haynes, John M., Mills, Richard J., Phelan, Dean G., Qian, Elizabeth L., Leitoguinho, Ana Rita, Arasaratnam, Deevina, Labonne, Tanya, Ng, Elizabeth S., Davis, Richard P., Casini, Simona, Passier, Robert, Hudson, James E., Porrello, Enzo R., Costa, Mauro W., Rafii, Arash, Curl, Clare L., Delbridge, Lea M., Harvey, Richard P., Oshlack, Alicia, Cheung, Michael M., Mummery, Christine L., Petrou, Stephen, Elefanty, Andrew G., Stanley, Edouard G., Elliott, David A.
Publicado 2018

Human-iPSC-Derived Cardiac Stromal Cells Enhance Maturation in 3D Cardiac Microtissues and Reveal Non-cardiomyocyte Contributions to Heart Disease

por Giacomelli, Elisa, Meraviglia, Viviana, Campostrini, Giulia, Cochrane, Amy, Cao, Xu, van Helden, Ruben W.J., Krotenberg Garcia, Ana, Mircea, Maria, Kostidis, Sarantos, Davis, Richard P., van Meer, Berend J., Jost, Carolina R., Koster, Abraham J., Mei, Hailiang, Míguez, David G., Mulder, Aat A., Ledesma-Terrón, Mario, Pompilio, Giulio, Sala, Luca, Salvatori, Daniela C.F., Slieker, Roderick C., Sommariva, Elena, de Vries, Antoine A.F., Giera, Martin, Semrau, Stefan, Tertoolen, Leon G.J., Orlova, Valeria V., Bellin, Milena, Mummery, Christine L.
Publicado 2020