Degenerative joint disease induced by repeated intra-articular injections of monosodium urate crystals in rats as investigated by translational imaging

por Accart, Nathalie, Dawson, Janet, Obrecht, Michael, Lambert, Christian, Flueckiger, Manuela, Kreider, Julie, Hatakeyama, Shinji, Richards, Peter J., Beckmann, Nicolau
Publicado 2022

Pharmacological inhibition of RORγt suppresses the Th17 pathway and alleviates arthritis in vivo

por Guendisch, Ulf, Weiss, Jessica, Ecoeur, Florence, Riker, Julia Christina, Kaupmann, Klemens, Kallen, Joerg, Hintermann, Samuel, Orain, David, Dawson, Janet, Billich, Andreas, Guntermann, Christine
Publicado 2017

Pathophysiological Consequences of a Break in S1P1-Dependent Homeostasis of Vascular Permeability Revealed by S1P1 Competitive Antagonism

por Bigaud, Marc, Dincer, Zuhal, Bollbuck, Birgit, Dawson, Janet, Beckmann, Nicolau, Beerli, Christian, Fishli-Cavelti, Gina, Nahler, Michaela, Angst, Daniela, Janser, Philipp, Otto, Heike, Rosner, Elisabeth, Hersperger, Rene, Bruns, Christian, Quancard, Jean
Publicado 2016

GPR91 senses extracellular succinate released from inflammatory macrophages and exacerbates rheumatoid arthritis

por Littlewood-Evans, Amanda, Sarret, Sophie, Apfel, Verena, Loesle, Perrine, Dawson, Janet, Zhang, Juan, Muller, Alban, Tigani, Bruno, Kneuer, Rainer, Patel, Saijel, Valeaux, Stephanie, Gommermann, Nina, Rubic-Schneider, Tina, Junt, Tobias, Carballido, José M.
Publicado 2016

Feasibility and physiological relevance of designing highly potent aminopeptidase-sparing leukotriene A4 hydrolase inhibitors

por Numao, Shin, Hasler, Franziska, Laguerre, Claire, Srinivas, Honnappa, Wack, Nathalie, Jäger, Petra, Schmid, Andres, Osmont, Arnaud, Röthlisberger, Patrik, Houguenade, Jeremy, Bergsdorf, Christian, Dawson, Janet, Carte, Nathalie, Hofmann, Andreas, Markert, Christian, Hardaker, Liz, Billich, Andreas, Wolf, Romain M., Penno, Carlos A., Bollbuck, Birgit, Miltz, Wolfgang, Röhn, Till A.
Publicado 2017

Inhibition of the Inositol Kinase Itpkb Augments Calcium Signaling in Lymphocytes and Reveals a Novel Strategy to Treat Autoimmune Disease

por Miller, Andrew T., Dahlberg, Carol, Sandberg, Mark L., Wen, Ben G., Beisner, Daniel R., Hoerter, John A. H., Parker, Albert, Schmedt, Christian, Stinson, Monique, Avis, Jacqueline, Cienfuegos, Cynthia, McPate, Mark, Tranter, Pamela, Gosling, Martin, Groot-Kormelink, Paul J., Dawson, Janet, Pan, Shifeng, Tian, Shin-Shay, Seidel, H. Martin, Cooke, Michael P.
Publicado 2015

Nonhematopoietic IRAK1 drives arthritis via neutrophil chemoattractants

por Hoyler, Thomas, Bannert, Bettina, André, Cédric, Beck, Damian, Boulay, Thomas, Buffet, David, Caesar, Nadja, Calzascia, Thomas, Dawson, Janet, Kyburz, Diego, Hennze, Robert, Huppertz, Christine, Littlewood-Evans, Amanda, Loetscher, Pius, Mertz, Kirsten D., Niwa, Satoru, Robert, Gautier, Rush, James S., Ruzzante, Giulia, Sarret, Sophie, Stein, Thomas, Touil, Ismahane, Wieczorek, Grazyna, Zipfel, Geraldine, Hawtin, Stuart, Junt, Tobias
Publicado 2022