Regulating BETs at central station

por Dawson, Mark A.
Publicado 2015

Endogenous retroviruses are a source of enhancers with oncogenic potential in acute myeloid leukaemia

por Deniz, Özgen, Ahmed, Mamataz, Todd, Christopher D., Rio-Machin, Ana, Dawson, Mark A., Branco, Miguel R.
Publicado 2020

Detection of cell-free microbial DNA using a contaminant-controlled analysis framework

por Zozaya-Valdés, Enrique, Wong, Stephen Q., Raleigh, Jeanette, Hatzimihalis, Athena, Ftouni, Sarah, Papenfuss, Anthony T., Sandhu, Shahneen, Dawson, Mark A., Dawson, Sarah-Jane
Publicado 2021

Benchmarking single-cell hashtag oligo demultiplexing methods

por Howitt, George, Feng, Yuzhou, Tobar, Lucas, Vassiliadis, Dane, Hickey, Peter, Dawson, Mark A, Ranganathan, Sarath, Shanthikumar, Shivanthan, Neeland, Melanie, Maksimovic, Jovana, Oshlack, Alicia
Publicado 2023

Genome-Wide Analysis of Transcriptional Reprogramming in Mouse Models of Acute Myeloid Leukaemia

por Bonadies, Nicolas, Foster, Samuel D., Chan, Wai-In, Kvinlaug, Brynn T., Spensberger, Dominik, Dawson, Mark A., Spooncer, Elaine, Whetton, Anthony D., Bannister, Andrew J., Huntly, Brian J., Göttgens, Berthold
Publicado 2011

Three Distinct Patterns of Histone H3Y41 Phosphorylation Mark Active Genes

por Dawson, Mark A., Foster, Samuel D., Bannister, Andrew J., Robson, Samuel C., Hannah, Rebecca, Wang, Xiaonan, Xhemalce, Blerta, Wood, Andrew D., Green, Anthony R., Göttgens, Berthold, Kouzarides, Tony
Publicado 2012

A combination strategy targeting enhancer plasticity exerts synergistic lethality against BETi-resistant leukemia cells

por Guo, Lei, Li, Jia, Zeng, Hongxiang, Guzman, Anna G., Li, Tingting, Lee, Minjung, Zhou, Yubin, Goodell, Margaret A., Stephan, Clifford, Davies, Peter J. A., Dawson, Mark A, Sun, Deqiang, Huang, Yun
Publicado 2020

Three-dimensional CRISPR screening reveals epigenetic interaction with anti-angiogenic therapy

por He, Michael Y., Halford, Michael M., Liu, Ruofei, Roy, James P., Grant, Zoe L., Coultas, Leigh, Thio, Niko, Gilan, Omer, Chan, Yih-Chih, Dawson, Mark A., Achen, Marc G., Stacker, Steven A.
Publicado 2021

LIF independent JAK signalling to chromatin in embryonic stem cells uncovered from an adult stem cell disease

por Griffiths, Dean S., Li, Juan, Dawson, Mark A., Trotter, Matthew W.B., Cheng, Yi-Han, Smith, Aileen M., Mansfield, William, Liu, Pentao, Kouzarides, Tony, Nichols, Jennifer, Bannister, Andrew J., Green, Anthony R, Göttgens, Berthold
Publicado 2010

Circulating tumour DNA in metastatic breast cancer to guide clinical trial enrolment and precision oncology: A cohort study

por Zivanovic Bujak, Andjelija, Weng, Chen-Fang, Silva, Maria João, Yeung, Miriam, Lo, Louisa, Ftouni, Sarah, Litchfield, Cassandra, Ko, Yi-An, Kuykhoven, Keilly, Van Geelen, Courtney, Chandrashekar, Sushma, Dawson, Mark A., Loi, Sherene, Wong, Stephen Q., Dawson, Sarah-Jane
Publicado 2020

P1212: RATIONALLY DESIGNED CHIMERIC PI3K-BET BROMODOMAIN INHIBITORS ELICIT CURATIVE RESPONSES IN MYC-DRIVEN LYMPHOMA

por Oh, Danielle H., MA, Xiao, He, Jackson, Kearney, Conor, Hogg, Simon J., Newbold, Andrea, Fraser, Peter, Jennings, Ian G., Brasacchio, Daniella, Susanto, Olivia, Yew Fong, Chun, Dawson, Mark A., Gruber, Emily, Kats, Lev, Johnstone, Ricky W., Thompson, Philip E., Shortt, Jake
Publicado 2023

TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS

por Deplus, Rachel, Delatte, Benjamin, Schwinn, Marie K, Defrance, Matthieu, Méndez, Jacqui, Murphy, Nancy, Dawson, Mark A, Volkmar, Michael, Putmans, Pascale, Calonne, Emilie, Shih, Alan H, Levine, Ross L, Bernard, Olivier, Mercher, Thomas, Solary, Eric, Urh, Marjeta, Daniels, Danette L, Fuks, François
Publicado 2013

BRD4 methylation by the methyltransferase SETD6 regulates selective transcription to control mRNA translation

por Vershinin, Zlata, Feldman, Michal, Werner, Thilo, Weil, Lital Estrella, Kublanovsky, Margarita, Abaev-Schneiderman, Elina, Sklarz, Menachem, Lam, Enid Y. N., Alasad, Khawla, Picaud, Sarah, Rotblat, Barak, McAdam, Ruth A., Chalifa-Caspi, Vered, Bantscheff, Marcus, Chapman, Trevor, Lewis, Huw D., Filippakopoulos, Panagis, Dawson, Mark A., Grandi, Paola, Prinjha, Rab K., Levy, Dan
Publicado 2021

Combined Targeting of JAK2 and Bcl-2/Bcl-xL to Cure Mutant JAK2-Driven Malignancies and Overcome Acquired Resistance to JAK2 Inhibitors

por Waibel, Michaela, Solomon, Vanessa S., Knight, Deborah A., Ralli, Rachael A., Kim, Sang-Kyu, Banks, Kellie-Marie, Vidacs, Eva, Virely, Clemence, Sia, Keith C.S., Bracken, Lauryn S., Collins-Underwood, Racquel, Drenberg, Christina, Ramsey, Laura B., Meyer, Sara C., Takiguchi, Megumi, Dickins, Ross A., Levine, Ross, Ghysdael, Jacques, Dawson, Mark A., Lock, Richard B., Mullighan, Charles G., Johnstone, Ricky W.
Publicado 2013

Circulating tumour DNA reflects treatment response and clonal evolution in chronic lymphocytic leukaemia

por Yeh, Paul, Hunter, Tane, Sinha, Devbarna, Ftouni, Sarah, Wallach, Elise, Jiang, Damian, Chan, Yih-Chih, Wong, Stephen Q., Silva, Maria Joao, Vedururu, Ravikiran, Doig, Kenneth, Lam, Enid, Arnau, Gisela Mir, Semple, Timothy, Wall, Meaghan, Zivanovic, Andjelija, Agarwal, Rishu, Petrone, Pasquale, Jones, Kate, Westerman, David, Blombery, Piers, Seymour, John F., Papenfuss, Anthony T., Dawson, Mark A., Tam, Constantine S., Dawson, Sarah-Jane
Publicado 2017

Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis

por Savitski, Mikhail M., Zinn, Nico, Faelth-Savitski, Maria, Poeckel, Daniel, Gade, Stephan, Becher, Isabelle, Muelbaier, Marcel, Wagner, Anne J., Strohmer, Katrin, Werner, Thilo, Melchert, Stephanie, Petretich, Massimo, Rutkowska, Anna, Vappiani, Johanna, Franken, Holger, Steidel, Michael, Sweetman, Gavain M., Gilan, Omer, Lam, Enid Y.N., Dawson, Mark A., Prinjha, Rab K., Grandi, Paola, Bergamini, Giovanna, Bantscheff, Marcus
Publicado 2018

Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes

por Sparbier, Christina E., Gillespie, Andrea, Gomez, Juliana, Kumari, Nishi, Motazedian, Ali, Chan, Kah Lok, Bell, Charles C., Gilan, Omer, Chan, Yih-Chih, Popp, Sarah, Gough, Daniel J., Eckersley-Maslin, Melanie A., Dawson, Sarah-Jane, Lehner, Paul J., Sutherland, Kate D., Ernst, Patricia, McGeehan, Gerard M., Lam, Enid Y. N., Burr, Marian L., Dawson, Mark A.
Publicado 2023

A druggable copper-signalling pathway that drives inflammation

por Solier, Stéphanie, Müller, Sebastian, Cañeque, Tatiana, Versini, Antoine, Mansart, Arnaud, Sindikubwabo, Fabien, Baron, Leeroy, Emam, Laila, Gestraud, Pierre, Pantoș, G. Dan, Gandon, Vincent, Gaillet, Christine, Wu, Ting-Di, Dingli, Florent, Loew, Damarys, Baulande, Sylvain, Durand, Sylvère, Sencio, Valentin, Robil, Cyril, Trottein, François, Péricat, David, Näser, Emmanuelle, Cougoule, Céline, Meunier, Etienne, Bègue, Anne-Laure, Salmon, Hélène, Manel, Nicolas, Puisieux, Alain, Watson, Sarah, Dawson, Mark A., Servant, Nicolas, Kroemer, Guido, Annane, Djillali, Rodriguez, Raphaël
Publicado 2023

An Erg-driven transcriptional program controls B cell lymphopoiesis

por Ng, Ashley P., Coughlan, Hannah D., Hediyeh-zadeh, Soroor, Behrens, Kira, Johanson, Timothy M., Low, Michael Sze Yuan, Bell, Charles C., Gilan, Omer, Chan, Yih-Chih, Kueh, Andrew J., Boudier, Thomas, Feltham, Rebecca, Gabrielyan, Anna, DiRago, Ladina, Hyland, Craig D., Ierino, Helen, Mifsud, Sandra, Viney, Elizabeth, Willson, Tracy, Dawson, Mark A., Allan, Rhys S., Herold, Marco J., Rogers, Kelly, Tarlinton, David M., Smyth, Gordon K., Davis, Melissa J., Nutt, Stephen L., Alexander, Warren S.
Publicado 2020

Pharmacologic Reduction of Mitochondrial Iron Triggers a Noncanonical BAX/BAK-Dependent Cell Death

por Garciaz, Sylvain, Guirguis, Andrew A., Müller, Sebastian, Brown, Fiona C., Chan, Yih-Chih, Motazedian, Ali, Rowe, Caitlin L., Kuzich, James A., Chan, Kah Lok, Tran, Kevin, Smith, Lorey, MacPherson, Laura, Liddicoat, Brian, Lam, Enid Y.N., Cañeque, Tatiana, Burr, Marian L., Litalien, Véronique, Pomilio, Giovanna, Poplineau, Mathilde, Duprez, Estelle, Dawson, Sarah-Jane, Ramm, Georg, Cox, Andrew G., Brown, Kristin K., Huang, David C.S., Wei, Andrew H., McArthur, Kate, Rodriguez, Raphaël, Dawson, Mark A.
Publicado 2022