Inhibition of Iron Uptake Is Responsible for Differential Sensitivity to V-ATPase Inhibitors in Several Cancer Cell Lines

por Straud, Sarah, Zubovych, Iryna, De Brabander, Jef K., Roth, Michael G.
Publicado 2010

Structural insights for selective disruption of Beclin 1 binding to Bcl-2

por Pan, Yun-Zu, Liang, Qiren, Tomchick, Diana R., De Brabander, Jef K., Rizo, Josep
Publicado 2023

Structural basis for itraconazole-mediated NPC1 inhibition

por Long, Tao, Qi, Xiaofeng, Hassan, Abdirahman, Liang, Qiren, De Brabander, Jef K., Li, Xiaochun
Publicado 2020

Identification of NPC1 as the target of U18666A, an inhibitor of lysosomal cholesterol export and Ebola infection

por Lu, Feiran, Liang, Qiren, Abi-Mosleh, Lina, Das, Akash, De Brabander, Jef K, Goldstein, Joseph L, Brown, Michael S
Publicado 2015

Therapeutic targeting truncated adenomatous polyposis coli (APC) proteins for the selective killing of colorectal cancer cells

por Zhang, Lu, Kim, Sang B, Eskiocak, Ugur, Posner, Bruce, Das, Priyabrata, Wright, Woodring E, De Brabander, Jef K, Shay, Jerry W
Publicado 2014

TK216 targets microtubules in Ewing sarcoma cells

por Povedano, Juan Manuel, Li, Vicky, Lake, Katherine E., Bai, Xin, Rallabandi, Rameshu, Kim, Jiwoong, Xie, Yang, De Brabander, Jef K., McFadden, David G.
Publicado 2022

A Multipronged Approach Establishes Covalent Modification of β-Tubulin as the Mode of Action of Benzamide Anti-cancer Toxins

por Povedano, Juan Manuel, Rallabandi, Rameshu, Bai, Xin, Ye, Xuecheng, Liou, Joel, Chen, Hong, Kim, Jiwoong, Xie, Yang, Posner, Bruce, Rice, Luke, De Brabander, Jef K., McFadden, David G.
Publicado 2020

The structure of importin α and the nuclear localization peptide of ChREBP, and small compound inhibitors of ChREBP–importin α interactions

por Jung, Hunmin, Takeshima, Tomomi, Nakagawa, Tsutomu, MacMillan, Karen S., Wynn, R. Max, Wang, Hanzhi, Sakiyama, Haruhiko, Wei, Shuguang, Li, Yang, Bruick, Richard K., Posner, Bruce A., De Brabander, Jef K., Uyeda, Kosaku
Publicado 2020

Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma

por Shi, Yufeng, Lim, S. Kyun, Liang, Qiren, Iyer, Swathi V., Wang, Hua-Yu, Wang, Zilai, Xie, Xuanhua, Sun, Daochun, Chen, Yu-Jung, Tabar, Viviane, Gutin, Philip, Williams, Noelle, De Brabander, Jef K., Parada, Luis F.
Publicado 2019

Reply to: The G protein preference of orexin receptors is currently an unresolved issue

por Yin, Jie, Kang, Yanyong, McGrath, Aaron P., Chapman, Karen, Sjodt, Megan, Kimura, Eiji, Okabe, Atsutoshi, Koike, Tatsuki, Miyanohana, Yuhei, Shimizu, Yuji, Rallabandi, Rameshu, Lian, Peng, Bai, Xiaochen, Flinspach, Mack, De Brabander, Jef K., Rosenbaum, Daniel M.
Publicado 2023

Molecular mechanism of the wake-promoting agent TAK-925

por Yin, Jie, Kang, Yanyong, McGrath, Aaron P., Chapman, Karen, Sjodt, Megan, Kimura, Eiji, Okabe, Atsutoshi, Koike, Tatsuki, Miyanohana, Yuhei, Shimizu, Yuji, Rallabandi, Rameshu, Lian, Peng, Bai, Xiaochen, Flinspach, Mack, De Brabander, Jef K., Rosenbaum, Daniel M.
Publicado 2022

Antiviral Properties of Chemical Inhibitors of Cellular Anti-Apoptotic Bcl-2 Proteins

por Bulanova, Daria, Ianevski, Aleksandr, Bugai, Andrii, Akimov, Yevhen, Kuivanen, Suvi, Paavilainen, Henrik, Kakkola, Laura, Nandania, Jatin, Turunen, Laura, Ohman, Tiina, Ala-Hongisto, Hanna, Pesonen, Hanna M., Kuisma, Marika S., Honkimaa, Anni, Walton, Emma L., Oksenych, Valentyn, Lorey, Martina B., Guschin, Dmitry, Shim, Jungmin, Kim, Jinhee, Than, Thoa T., Chang, So Young, Hukkanen, Veijo, Kulesskiy, Evgeny, Marjomaki, Varpu S., Julkunen, Ilkka, Nyman, Tuula A., Matikainen, Sampsa, Saarela, Jani S., Sane, Famara, Hober, Didier, Gabriel, Gülsah, De Brabander, Jef K., Martikainen, Miika, Windisch, Marc P., Min, Ji-Young, Bruzzone, Roberto, Aittokallio, Tero, Vähä-Koskela, Markus, Vapalahti, Olli, Pulk, Arto, Velagapudi, Vidya, Kainov, Denis E.
Publicado 2017