Nucleotide precursors prevent folic acid-resistant neural tube defects in the mouse

por Leung, Kit-Yi, De Castro, Sandra C.P., Savery, Dawn, Copp, Andrew J., Greene, Nicholas D.E.
Publicado 2013

Glycine Cleavage System H Protein Is Essential for Embryonic Viability, Implying Additional Function Beyond the Glycine Cleavage System

por Leung, Kit-Yi, De Castro, Sandra C. P., Galea, Gabriel L., Copp, Andrew J., Greene, Nicholas D. E.
Publicado 2021

Folate metabolite profiling of different cell types and embryos suggests variation in folate one-carbon metabolism, including developmental changes in human embryonic brain

por Leung, Kit-Yi, De Castro, Sandra C. P., Cabreiro, Filipe, Gustavsson, Peter, Copp, Andrew J., Greene, Nicholas D. E.
Publicado 2013

Lamin B1 Polymorphism Influences Morphology of the Nuclear Envelope, Cell Cycle Progression, and Risk of Neural Tube Defects in Mice

por De Castro, Sandra C. P., Malhas, Ashraf, Leung, Kit-Yi, Gustavsson, Peter, Vaux, David J., Copp, Andrew J., Greene, Nicholas D. E.
Publicado 2012

Neural tube closure depends on expression of Grainyhead-like 3 in multiple tissues

por De Castro, Sandra C.P., Hirst, Caroline S., Savery, Dawn, Rolo, Ana, Lickert, Heiko, Andersen, Bogi, Copp, Andrew J., Greene, Nicholas D.E.
Publicado 2018

Formate supplementation enhances folate-dependent nucleotide biosynthesis and prevents spina bifida in a mouse model of folic acid-resistant neural tube defects

por Sudiwala, Sonia, De Castro, Sandra C.P., Leung, Kit-Yi, Brosnan, John T., Brosnan, Margaret E., Mills, Kevin, Copp, Andrew J., Greene, Nicholas D.E.
Publicado 2016

Spinal neural tube closure depends on regulation of surface ectoderm identity and biomechanics by Grhl2

por Nikolopoulou, Evanthia, Hirst, Caroline S., Galea, Gabriel, Venturini, Christina, Moulding, Dale, Marshall, Abigail R., Rolo, Ana, De Castro, Sandra C. P., Copp, Andrew J., Greene, Nicholas D. E.
Publicado 2019

Regulation of glycine metabolism by the glycine cleavage system and conjugation pathway in mouse models of non‐ketotic hyperglycinemia

por Leung, Kit‐Yi, De Castro, Sandra C. P., Santos, Chloe, Savery, Dawn, Prunty, Helen, Gold‐Diaz, Diana, Bennett, Stuart, Heales, Simon, Copp, Andrew J., Greene, Nicholas D. E.
Publicado 2020

Cellular mechanisms underlying Pax3-related neural tube defects and their prevention by folic acid

por Sudiwala, Sonia, Palmer, Alexandra, Massa, Valentina, Burns, Alan J., Dunlevy, Louisa P. E., de Castro, Sandra C. P., Savery, Dawn, Leung, Kit-Yi, Copp, Andrew J., Greene, Nicholas D. E.
Publicado 2019

Dynamic acetylation profile during mammalian neurulation

por Massa, Valentina, Avagliano, Laura, Grazioli, Paolo, De Castro, Sandra C. P., Parodi, Chiara, Savery, Dawn, Vergani, Patrizia, Cuttin, Serena, Doi, Patrizia, Bulfamante, Gaetano, Copp, Andrew J., Greene, Nicholas D. E.
Publicado 2019

Overexpression of Grainyhead-like 3 causes spina bifida and interacts genetically with mutant alleles of Grhl2 and Vangl2 in mice

por De Castro, Sandra C P, Gustavsson, Peter, Marshall, Abigail R, Gordon, William M, Galea, Gabriel, Nikolopoulou, Evanthia, Savery, Dawn, Rolo, Ana, Stanier, Philip, Andersen, Bogi, Copp, Andrew J, Greene, Nicholas D E
Publicado 2018

Diffusion microscopic MRI of the mouse embryo: Protocol and practical implementation in the splotch mouse model

por Norris, Francesca C., Siow, Bernard M., Cleary, Jon O., Wells, Jack A., De Castro, Sandra C.P., Ordidge, Roger J., Greene, Nicholas D.E., Copp, Andrew J., Scambler, Peter J., Alexander, Daniel. C., Lythgoe, Mark F.
Publicado 2014

A non-coding insertional mutation of Grhl2 causes gene over-expression and multiple structural anomalies including cleft palate, spina bifida and encephalocele

por Crane-Smith, Zoe, De Castro, Sandra C P, Nikolopoulou, Evanthia, Wolujewicz, Paul, Smedley, Damian, Lei, Yunping, Mather, Emma, Santos, Chloe, Hopkinson, Mark, Pitsillides, Andrew A, Finnell, Richard H, Ross, M Elisabeth, Copp, Andrew J, Greene, Nicholas D E
Publicado 2023

Over-expression of Grhl2 causes spina bifida in the Axial defects mutant mouse

por Brouns, Madeleine R., De Castro, Sandra C.P., Terwindt-Rouwenhorst, Els A., Massa, Valentina, Hekking, Johan W., Hirst, Caroline S., Savery, Dawn, Munts, Chantal, Partridge, Darren, Lamers, Wout, Köhler, Eleonore, van Straaten, Henny W., Copp, Andrew J., Greene, Nicholas D.E.
Publicado 2011