Selective killing of spinal cord neural stem cells impairs locomotor recovery in a mouse model of spinal cord injury

por Cusimano, Melania, Brambilla, Elena, Capotondo, Alessia, De Feo, Donatella, Tomasso, Antonio, Comi, Giancarlo, D’Adamo, Patrizia, Muzio, Luca, Martino, Gianvito
Publicado 2018

Myeloid cells as target of fingolimod action in multiple sclerosis

por Di Dario, Marco, Colombo, Emanuela, Govi, Chiara, De Feo, Donatella, Messina, Maria José, Romeo, Marzia, Sangalli, Francesca, Moiola, Lucia, Rodegher, Mariaemma, Martino, Gianvito, Martinelli, Vittorio, Comi, Giancarlo, Farina, Cinthia
Publicado 2015

IMMU-16. INTRA-TUMOURAL IL-12 DELIVERY ENABLES CAR T-CELL IMMUNOTHERAPY FOR HIGH-GRADE GLIOMA

por Agliardi, Giulia, Liuzzi, Anna Rita, Hotblack, Alastair, De Feo, Donatella, Núñez, Nicolás, Friebel, Ekaterina, Nannini, Francesco, Roberts, Thomas, Ramasawmy, Rajiv, Stowe, Cassandra, Williams, Iwan, Siow, Bernard, Lythgoe, Mark, Kalber, Tammy, Quezada, Sergio, Pule, Martin, Tugues, Sonia, Becher, Burkhard, Straathof, Karin
Publicado 2020

IL-12 sensing in neurons induces neuroprotective CNS tissue adaptation and attenuates neuroinflammation in mice

por Andreadou, Myrto, Ingelfinger, Florian, De Feo, Donatella, Cramer, Teresa L. M., Tuzlak, Selma, Friebel, Ekaterina, Schreiner, Bettina, Eede, Pascale, Schneeberger, Shirin, Geesdorf, Maria, Ridder, Frederike, Welsh, Christina A., Power, Laura, Kirschenbaum, Daniel, Tyagarajan, Shiva K., Greter, Melanie, Heppner, Frank L., Mundt, Sarah, Becher, Burkhard
Publicado 2023

Twin study reveals non-heritable immune perturbations in multiple sclerosis

por Ingelfinger, Florian, Gerdes, Lisa Ann, Kavaka, Vladyslav, Krishnarajah, Sinduya, Friebel, Ekaterina, Galli, Edoardo, Zwicky, Pascale, Furrer, Reinhard, Peukert, Christian, Dutertre, Charles-Antoine, Eglseer, Klara Magdalena, Ginhoux, Florent, Flierl-Hecht, Andrea, Kümpfel, Tania, De Feo, Donatella, Schreiner, Bettina, Mundt, Sarah, Kerschensteiner, Martin, Hohlfeld, Reinhard, Beltrán, Eduardo, Becher, Burkhard
Publicado 2022

Intratumoral IL-12 delivery empowers CAR-T cell immunotherapy in a pre-clinical model of glioblastoma

por Agliardi, Giulia, Liuzzi, Anna Rita, Hotblack, Alastair, De Feo, Donatella, Núñez, Nicolás, Stowe, Cassandra L., Friebel, Ekaterina, Nannini, Francesco, Rindlisbacher, Lukas, Roberts, Thomas A., Ramasawmy, Rajiv, Williams, Iwan P., Siow, Bernard M., Lythgoe, Mark F., Kalber, Tammy L., Quezada, Sergio A., Pule, Martin A., Tugues, Sonia, Straathof, Karin, Becher, Burkhard
Publicado 2021

Single-cell profiling of myasthenia gravis identifies a pathogenic T cell signature

por Ingelfinger, Florian, Krishnarajah, Sinduya, Kramer, Michael, Utz, Sebastian G., Galli, Edoardo, Lutz, Mirjam, Zwicky, Pascale, Akarca, Ayse U., Jurado, Nicole Puertas, Ulutekin, Can, Bamert, David, Widmer, Corinne C., Piccoli, Luca, Sallusto, Federica, Núñez, Nicolás G., Marafioti, Teresa, Schneiter, Didier, Opitz, Isabelle, Lanzavecchia, Antonio, Jung, Hans H., De Feo, Donatella, Mundt, Sarah, Schreiner, Bettina, Becher, Burkhard
Publicado 2021

Distinct immunological signatures discriminate severe COVID-19 from non-SARS-CoV-2-driven critical pneumonia

por Kreutmair, Stefanie, Unger, Susanne, Núñez, Nicolás Gonzalo, Ingelfinger, Florian, Alberti, Chiara, De Feo, Donatella, Krishnarajah, Sinduya, Kauffmann, Manuel, Friebel, Ekaterina, Babaei, Sepideh, Gaborit, Benjamin, Lutz, Mirjam, Jurado, Nicole Puertas, Malek, Nisar P., Goepel, Siri, Rosenberger, Peter, Häberle, Helene A., Ayoub, Ikram, Al-Hajj, Sally, Nilsson, Jakob, Claassen, Manfred, Liblau, Roland, Martin-Blondel, Guillaume, Bitzer, Michael, Roquilly, Antoine, Becher, Burkhard
Publicado 2021

Distinct immunological signatures discriminate severe COVID-19 from non-SARS-CoV-2-driven critical pneumonia

por Kreutmair, Stefanie, Unger, Susanne, Núñez, Nicolás Gonzalo, Ingelfinger, Florian, Alberti, Chiara, De Feo, Donatella, Krishnarajah, Sinduya, Kauffmann, Manuel, Friebel, Ekaterina, Babaei, Sepideh, Gaborit, Benjamin, Lutz, Mirjam, Jurado, Nicole Puertas, Malek, Nisar P., Goepel, Siri, Rosenberger, Peter, Häberle, Helene A., Ayoub, Ikram, Al-Hajj, Sally, Nilsson, Jakob, Claassen, Manfred, Liblau, Roland, Martin-Blondel, Guillaume, Bitzer, Michael, Roquilly, Antoine, Becher, Burkhard
Publicado 2022

Preexisting comorbidities shape the immune response associated with severe COVID-19

por Kreutmair, Stefanie, Kauffmann, Manuel, Unger, Susanne, Ingelfinger, Florian, Núñez, Nicolás Gonzalo, Alberti, Chiara, De Feo, Donatella, Krishnarajah, Sinduya, Friebel, Ekaterina, Ulutekin, Can, Babaei, Sepideh, Gaborit, Benjamin, Lutz, Mirjam, Jurado, Nicole Puertas, Malek, Nisar P., Göpel, Siri, Rosenberger, Peter, Häberle, Helene A., Ayoub, Ikram, Al-Hajj, Sally, Claassen, Manfred, Liblau, Roland, Martin-Blondel, Guillaume, Bitzer, Michael, Roquilly, Antoine, Becher, Burkhard
Publicado 2022

Oncogenic Kras(G12D) causes myeloproliferation via NLRP3 inflammasome activation

por Hamarsheh, Shaima’a, Osswald, Lena, Saller, Benedikt S., Unger, Susanne, De Feo, Donatella, Vinnakota, Janaki Manoja, Konantz, Martina, Uhl, Franziska M., Becker, Heiko, Lübbert, Michael, Shoumariyeh, Khalid, Schürch, Christoph, Andrieux, Geoffroy, Venhoff, Nils, Schmitt-Graeff, Annette, Duquesne, Sandra, Pfeifer, Dietmar, Cooper, Matthew A., Lengerke, Claudia, Boerries, Melanie, Duyster, Justus, Niemeyer, Charlotte M., Erlacher, Miriam, Blazar, Bruce R., Becher, Burkard, Groß, Olaf, Brummer, Tilman, Zeiser, Robert
Publicado 2020

Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas

por Aslan, Katrin, Turco, Verena, Blobner, Jens, Sonner, Jana K., Liuzzi, Anna Rita, Núñez, Nicolás Gonzalo, De Feo, Donatella, Kickingereder, Philipp, Fischer, Manuel, Green, Ed, Sadik, Ahmed, Friedrich, Mirco, Sanghvi, Khwab, Kilian, Michael, Cichon, Frederik, Wolf, Lara, Jähne, Kristine, von Landenberg, Anna, Bunse, Lukas, Sahm, Felix, Schrimpf, Daniel, Meyer, Jochen, Alexander, Allen, Brugnara, Gianluca, Röth, Ralph, Pfleiderer, Kira, Niesler, Beate, von Deimling, Andreas, Opitz, Christiane, Breckwoldt, Michael O., Heiland, Sabine, Bendszus, Martin, Wick, Wolfgang, Becher, Burkhard, Platten, Michael
Publicado 2020