Endothelial function in migraine: a cross-sectional study

por Vanmolkot, Floris H, de Hoon, Jan N
Publicado 2010

Effective analgesia after cesarean delivery needs pharmacokinetic input

por Kulo, Aida, de Hoon, Jan, Mulabegovic, Nedzad, Allegaert, Karel
Publicado 2012

Renal Side Effects of Non-Steroidal Anti-Inflammatory Drugs in Neonates

por Allegaert, Karel, de Hoon, Jan, Debeer, Anne, Gewillig, Marc
Publicado 2014

Biochemical tolerance during low dose propylene glycol exposure in neonates: A formulation-controlled evaluation

por Kulo, Aida, Smits, Anne, Naulaers, Gunnar, de Hoon, Jan, Allegaert, Karel
Publicado 2012

Pharmacokinetics during therapeutic hypothermia for neonatal hypoxic ischaemic encephalopathy: a literature review

por Lutz, Isabelle Claire, Allegaert, Karel, de Hoon, Jan N, Marynissen, Heleen
Publicado 2020

Simultaneous Semi-Mechanistic Population Pharmacokinetic Modeling Analysis of Enalapril and Enalaprilat Serum and Urine Concentrations From Child Appropriate Orodispersible Minitab...

por Faisal, Muhammad, Cawello, Willi, Burckhardt, Bjoern B., de Hoon, Jan, Laer, Stephanie
Publicado 2019

The Impact of Caesarean Delivery on Paracetamol and Ketorolac Pharmacokinetics: A Paired Analysis

por Kulo, Aida, van Calsteren, Kristel, Verbesselt, Rene, Smits, Anne, Devlieger, Roland, de Hoon, Jan, Allegaert, Karel
Publicado 2012

The New First-in-Human EMA Guideline: Disruptive or Constructive? Outcomes From the First EUFEMED Discussion Forum

por Breithaupt-Grögler, Kerstin, Hardman, Tim, de Hoon, Jan, Donazzolo, Yves, Rottey, Sylvie, Sourgens, Hildegard, Stringer, Steffan
Publicado 2019

Developmental changes rather than repeated administration drive paracetamol glucuronidation in neonates and infants

por Krekels, Elke H. J., van Ham, Saskia, Allegaert, Karel, de Hoon, Jan, Tibboel, Dick, Danhof, Meindert, Knibbe, Catherijne A. J.
Publicado 2015

Phase 1, randomized, parallel-group, double-blind, placebo-controlled trial to evaluate the effects of erenumab (AMG 334) and concomitant sumatriptan on blood pressure in healthy v...

por de Hoon, Jan, Van Hecken, Anne, Vandermeulen, Corinne, Herbots, Marissa, Kubo, Yumi, Lee, Ed, Eisele, Osa, Vargas, Gabriel, Gabriel, Kristin
Publicado 2018

Human biodistribution and dosimetry of [(11)C]-UCB-J, a PET radiotracer for imaging synaptic density

por Cawthorne, Christopher, Maguire, Paul, Mercier, Joel, Sciberras, David, Serdons, Kim, Bormans, Guy, de Hoon, Jan, Van Laere, Koen, Koole, Michel
Publicado 2021

Pharmacokinetic-Pharmacodynamic Relationship of Erenumab (AMG 334) and Capsaicin-Induced Dermal Blood Flow in Healthy and Migraine Subjects

por Vu, Thuy, Ma, Peiming, Chen, Jiyun Sunny, de Hoon, Jan, Van Hecken, Anne, Yan, Lucy, Wu, Liviawati Sutjandra, Hamilton, Lisa, Vargas, Gabriel
Publicado 2017

Minimally invasive quantification of cerebral P2X7R occupancy using dynamic [(18)F]JNJ-64413739 PET and MRA-driven image derived input function

por Mertens, Nathalie, Schmidt, Mark E., Hijzen, Anja, Van Weehaeghe, Donatienne, Ravenstijn, Paulien, Depre, Marleen, de Hoon, Jan, Van Laere, Koen, Koole, Michel
Publicado 2021

First‐in‐human development of a pharmacodynamic biomarker for PAC(1) receptor antagonists using intradermal injections of maxadilan

por Marynissen, Heleen, Buntinx, Linde, Bamps, Dorien, Depre, Marleen, Ampe, Els, Van Hecken, Anne, Gabriel, Kristin, Sands, Steve, Vargas, Gabriel, de Hoon, Jan
Publicado 2022

Paracetamol pharmacokinetics and metabolism in young women

por Allegaert, Karel, Peeters, Mariska Y., Beleyn, Bjorn, Smits, Anne, Kulo, Aida, van Calsteren, Kristel, Deprest, Jan, de Hoon, Jan, Knibbe, Catherijne A. J.
Publicado 2015

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the CGRP Binding Monoclonal Antibody LY2951742 (Galcanezumab) in Healthy Volunteers

por Monteith, David, Collins, Emily C., Vandermeulen, Corinne, Van Hecken, Anne, Raddad, Eyas, Scherer, Joel C., Grayzel, David, Schuetz, Thomas J., de Hoon, Jan
Publicado 2017

Antenatal sildenafil administration to prevent pulmonary hypertension in congenital diaphragmatic hernia (SToP-PH): study protocol for a phase I/IIb placenta transfer and safety st...

por Russo, Francesca Maria, Benachi, Alexandra, Van Mieghem, Tim, De Hoon, Jan, Van Calsteren, Kristel, Annaert, Pieter, Tréluyer, Jean-Marc, Allegaert, Karel, Deprest, Jan
Publicado 2018

EUFEMED London Conference 2017: Exploratory Medicines Development: Innovation and Risk Management

por Van Bortel, Luc, Sourgens, Hildegard, Breithaupt-Grögler, Kerstin, Caplain, Henri, Donazzolo, Yves, Klingmann, Ingrid, Hammond, Michael, Hardman, Timothy C., Stringer, Steffan, de Hoon, Jan
Publicado 2018

Pharmacokinetics of Oral Rebaudioside A in Patients with Type 2 Diabetes Mellitus and Its Effects on Glucose Homeostasis: A Placebo-Controlled Crossover Trial

por Simoens, Caroline, Philippaert, Koenraad, Wuyts, Caroline, Goscinny, Séverine, Van Hoeck, Els, Van Loco, Joris, Billen, Jaak, de Hoon, Jan, Ampe, Els, Vangoitsenhoven, Roman, Mertens, Ann, Vennekens, Rudi, Van der Schueren, Bart
Publicado 2022

Clinical validation of the novel HDAC6 radiotracer [(18)F]EKZ-001 in the human brain

por Koole, Michel, Van Weehaeghe, Donatienne, Serdons, Kim, Herbots, Marissa, Cawthorne, Christopher, Celen, Sofie, Schroeder, Frederick A., Hooker, Jacob M., Bormans, Guy, de Hoon, Jan, Kranz, Janice E., Van Laere, Koen, Gilbert, Tonya M.
Publicado 2020