Modulation of HIV-1 Gag NC/p1 cleavage efficiency affects protease inhibitor resistance and viral replicative capacity

por van Maarseveen, Noortje M, Andersson, Dan, Lepšík, Martin, Fun, Axel, Schipper, Pauline J, de Jong, Dorien, Boucher, Charles AB, Nijhuis, Monique
Publicado 2012

A combinational CRISPR/Cas9 gene-editing approach can halt HIV replication and prevent viral escape

por Lebbink, Robert Jan, de Jong, Dorien C. M., Wolters, Femke, Kruse, Elisabeth M., van Ham, Petra M., Wiertz, Emmanuel J. H. J., Nijhuis, Monique
Publicado 2017

Differential In Vitro Kinetics of Drug Resistance Mutation Acquisition in HIV-1 RT of Subtypes B and C

por Cunha, Rodrigo D., Abreu, Celina M., Gonzalez, Luis M. F., Nijhuis, Monique, de Jong, Dorien, Aguiar, Renato S., Afonso, Adriana O., Brindeiro, Rodrigo M., Tanuri, Amilcar
Publicado 2012

Development of sensitive ddPCR assays to reliably quantify the proviral DNA reservoir in all common circulating HIV subtypes and recombinant forms

por Bosman, Kobus J, Wensing, Annemarie MJ, Pijning, Aster E, van Snippenberg, Wilco J, van Ham, Petra M, de Jong, Dorien MC, Hoepelman, Andy IM, Nijhuis, Monique
Publicado 2018

Persistence of frequently transmitted drug-resistant HIV-1 variants can be explained by high viral replication capacity

por Pingen, Marieke, Wensing, Annemarie MJ, Fransen, Katrien, De Bel, Annelies, de Jong, Dorien, Hoepelman, Andy IM, Magiorkinis, Emmanouil, Paraskevis, Dimitrios, Lunar, Maja M, Poljak, Mario, Nijhuis, Monique, Boucher, Charles AB
Publicado 2014

A randomized study of intensified antiretroviral treatment monitoring versus standard-of-care for prevention of drug resistance and antiretroviral treatment switch

por Hermans, Lucas E., Ter Heine, Rob, Schuurman, Rob, Tempelman, Hugo A., Burger, David M., Vervoort, Sigrid C.J.M., Deville, Walter L.J.M., De Jong, Dorien, Venter, Willem D.F., Nijhuis, Monique, Wensing, Annemarie M.J.
Publicado 2022

Directing HIV-1 for degradation by non-target cells, using bi-specific single-chain llama antibodies

por Stam, Jord C., de Maat, Steven, de Jong, Dorien, Arens, Mathia, van Lint, Fenna, Gharu, Lavina, van Roosmalen, Mark H., Roovers, Rob C., Strokappe, Nika M., Wagner, Ralf, Kliche, Alexander, de Haard, Hans J., van Bergen en Henegouwen, Paul M., Nijhuis, Monique, Verrips, C. Theo
Publicado 2022

A Novel Substrate-Based HIV-1 Protease Inhibitor Drug Resistance Mechanism

por Nijhuis, Monique, van Maarseveen, Noortje M, Lastere, Stephane, Schipper, Pauline, Coakley, Eoin, Glass, Bärbel, Rovenska, Mirka, de Jong, Dorien, Chappey, Colombe, Goedegebuure, Irma W, Heilek-Snyder, Gabrielle, Dulude, Dominic, Cammack, Nick, Brakier-Gingras, Lea, Konvalinka, Jan, Parkin, Neil, Kräusslich, Hans-Georg, Brun-Vezinet, Francoise, Boucher, Charles A. B
Publicado 2007

In-depth Characterization of Vaccine Breakthrough Infections With SARS-CoV-2 Among Health Care Workers in a Dutch Academic Medical Center

por Rümke, Lidewij W, Groenveld, Femke C, van Os, Yvonne M G, Praest, Patrique, Tanja, Anniek A N, de Jong, Dorien T C M, Symons, Jori, Schuurman, Rob, Reinders, Tessa, Hofstra, L Marije, Nierkens, Stefan, Thijsen, Steven F T, Heron, Michiel, Lebbink, Robert-Jan, Beekman, Jeffrey M, Nijhuis, Monique, Wensing, Annemarie M J
Publicado 2021

Immune activation correlates with and predicts CXCR4 co-receptor tropism switch in HIV-1 infection

por Connell, Bridgette J., Hermans, Lucas E., Wensing, Annemarie M. J., Schellens, Ingrid, Schipper, Pauline J., van Ham, Petra M., de Jong, Dorien T. C. M., Otto, Sigrid, Mathe, Tholakele, Moraba, Robert, Borghans, José A. M., Papathanasopoulos, Maria A., Kruize, Zita, Venter, Francois W. D., Kootstra, Neeltje A., Tempelman, Hugo, Tesselaar, Kiki, Nijhuis, Monique
Publicado 2020

Autopsy Study Defines Composition and Dynamics of the HIV-1 Reservoir after Allogeneic Hematopoietic Stem Cell Transplantation with CCR5Δ32/Δ32 Donor Cells

por Huyveneers, Laura E. P., Bruns, Anke, Stam, Arjen, Ellerbroek, Pauline, de Jong, Dorien, Nagy, Noémi A., Gumbs, Stephanie B. H., Tesselaar, Kiki, Bosman, Kobus, Salgado, Maria, Hütter, Gero, Brosens, Lodewijk A. A., Kwon, Mi, Diez Martin, Jose, van der Meer, Jan T. M., de Kort, Theun M., Sáez-Cirión, Asier, Schulze zur Wiesch, Julian, Boelens, Jaap Jan, Martinez-Picado, Javier, Kuball, Jürgen H. E., Wensing, Annemarie M. J., Nijhuis, Monique
Publicado 2022