The importance of systematic approaches in the study of emesis

por De Jonghe, Bart C, Horn, Charles C
Publicado 2015

The Role of GIP in the Regulation of GLP-1 Satiety and Nausea

por Hayes, Matthew R., Borner, Tito, De Jonghe, Bart C.
Publicado 2021

Ablation of intact hypothalamic and/or hindbrain TrkB signaling leads to perturbations in energy balance

por Ozek, Ceren, Zimmer, Derek J., De Jonghe, Bart C., Kalb, Robert G., Bence, Kendra K.
Publicado 2015

Single nuclei RNA sequencing of the rat AP and NTS following GDF15 treatment

por Reiner, Benjamin C., Crist, Richard C., Borner, Tito, Doyle, Robert P., Hayes, Matthew R., De Jonghe, Bart C.
Publicado 2021

Myocardial apoptosis and mesenchymal stem cells with acute exercise

por Arisi, Maria F., Chirico, Erica N., Sebeny, Roxanne, Muthukumaran, Geetha, Mu, Anbin, De Jonghe, Bart C., Margulies, Kenneth B., Libonati, Joseph R.
Publicado 2017

Creation of a Peptide Antagonist of the GFRAL–RET Receptor Complex for the Treatment of GDF15-Induced Malaise

por Borner, Tito, Tinsley, Ian C., Milliken, Brandon T., Doebley, Sarah A., Najjar, Nicholas R., Kerwood, Deborah J., De Jonghe, Bart C., Hayes, Matthew R., Doyle, Robert P.
Publicado 2023

Hypophagia induced by salmon calcitonin, but not by amylin, is partially driven by malaise and is mediated by CGRP neurons

por Boccia, Lavinia, Borner, Tito, Ghidewon, Misgana Y., Kulka, Patricia, Piffaretti, Chiara, Doebley, Sarah A., De Jonghe, Bart C., Grill, Harvey J., Lutz, Thomas A., Le Foll, Christelle
Publicado 2022

GIP receptor agonism blocks chemotherapy-induced nausea and vomiting

por Borner, Tito, Reiner, Benjamin C., Crist, Richard C., Furst, C. Daniel, Doebley, Sarah A., Halas, Julia G., Ai, Minrong, Samms, Ricardo J., De Jonghe, Bart C., Hayes, Matthew R.
Publicado 2023

Design and Evaluation of Peptide Dual-Agonists of GLP-1 and NPY2 Receptors for Glucoregulation and Weight Loss with Mitigated Nausea and Emesis

por Milliken, Brandon T., Elfers, Clinton, Chepurny, Oleg G., Chichura, Kylie S., Sweet, Ian R., Borner, Tito, Hayes, Matthew R., De Jonghe, Bart C., Holz, George G., Roth, Christian L., Doyle, Robert P.
Publicado 2021

Synthesis, Optimization, and Biological Evaluation of Corrinated Conjugates of the GLP-1R Agonist Exendin-4

por Tinsley, Ian C., Borner, Tito, Swanson, MacKenzie L., Chepurny, Oleg G., Doebley, Sarah A., Kamat, Varun, Sweet, Ian R., Holz, George G., Hayes, Matthew R., De Jonghe, Bart C., Doyle, Robert P.
Publicado 2021

Peripherally restricted oxytocin is sufficient to reduce food intake and motivation, while CNS entry is required for locomotor and taste avoidance effects

por Asker, Mohammed, Krieger, Jean‐Philippe, Liles, Amber, Tinsley, Ian C., Borner, Tito, Maric, Ivana, Doebley, Sarah, Furst, C. Daniel, Börchers, Stina, Longo, Francesco, Bhat, Yashaswini R., De Jonghe, Bart C., Hayes, Matthew R., Doyle, Robert P., Skibicka, Karolina P.
Publicado 2023

GIPR Agonism Inhibits PYY-Induced Nausea-Like Behavior

por Samms, Ricardo J., Cosgrove, Richard, Snider, Brandy M., Furber, Ellen C., Droz, Brian A., Briere, Daniel A., Dunbar, James, Dogra, Mridula, Alsina-Fernandez, Jorge, Borner, Tito, De Jonghe, Bart C., Hayes, Matthew R., Coskun, Tamer, Sloop, Kyle W., Emmerson, Paul J., Ai, Minrong
Publicado 2022

GIP Receptor Agonism Attenuates GLP-1 Receptor Agonist–Induced Nausea and Emesis in Preclinical Models

por Borner, Tito, Geisler, Caroline E., Fortin, Samantha M., Cosgrove, Richard, Alsina-Fernandez, Jorge, Dogra, Mridula, Doebley, Sarah, Sanchez-Navarro, Marcos J., Leon, Rosa M., Gaisinsky, Jane, White, Arianna, Bamezai, Ankur, Ghidewon, Misgana Y., Grill, Harvey J., Crist, Richard C., Reiner, Benjamin C., Ai, Minrong, Samms, Ricardo J., De Jonghe, Bart C., Hayes, Matthew R.
Publicado 2021

Human OPRM1 and murine Oprm1 promoter driven viral constructs for genetic access to μ-opioidergic cell types

por Salimando, Gregory J., Tremblay, Sébastien, Kimmey, Blake A., Li, Jia, Rogers, Sophie A., Wojick, Jessica A., McCall, Nora M., Wooldridge, Lisa M., Rodrigues, Amrith, Borner, Tito, Gardiner, Kristin L., Jayakar, Selwyn S., Singeç, Ilyas, Woolf, Clifford J., Hayes, Matthew R., De Jonghe, Bart C., Bennett, F. Christian, Bennett, Mariko L., Blendy, Julie A., Platt, Michael L., Creasy, Kate Townsend, Renthal, William R., Ramakrishnan, Charu, Deisseroth, Karl, Corder, Gregory
Publicado 2023