Drug resistance in protozoan parasites

por de Koning, Harry P.
Publicado 2017

Transport proteins determine drug sensitivity and resistance in a protozoan parasite, Trypanosoma brucei

por Munday, Jane C., Settimo, Luca, de Koning, Harry P.
Publicado 2015

An improved and highly sensitive microfluorimetric method for assessing susceptibility of Plasmodium falciparum to antimalarial drugs in vitro

por Quashie, Neils B, de Koning, Harry P, Ranford-Cartwright, Lisa C
Publicado 2006

Uptake of purines in Plasmodium falciparum-infected human erythrocytes is mostly mediated by the human Equilibrative Nucleoside Transporter and the human Facilitative Nucleobase Tr...

por Quashie, Neils B, Ranford-Cartwright, Lisa C, de Koning, Harry P
Publicado 2010

The ever unfolding story of cAMP signaling in trypanosomatids: vive la difference!

por Tagoe, Daniel N. A., Kalejaiye, Titilola D., de Koning, Harry P.
Publicado 2015

Exploiting the Achilles’ heel of membrane trafficking in trypanosomes

por Zoltner, Martin, Horn, David, de Koning, Harry P, Field, Mark C
Publicado 2016

Antileishmanial and antitrypanosomal activity of symmetrical dibenzyl-substituted α,β-unsaturated carbonyl-based compounds

por Alkhaldi, Abdulsalam AM, de Koning, Harry P, Bukhari, Syed Nasir Abbas
Publicado 2019

Trypanosoma brucei adenine-phosphoribosyltransferases mediate adenine salvage and aminopurinol susceptibility but not adenine toxicity()

por Lüscher, Alexandra, Lamprea-Burgunder, Estelle, Graf, Fabrice E., de Koning, Harry P., Mäser, Pascal
Publicado 2013

Increasing Collaborative Discussion in Case-Based Learning Improves Student Engagement and Knowledge Acquisition

por Sartania, Nana, Sneddon, Sharon, Boyle, James G., McQuarrie, Emily, de Koning, Harry P.
Publicado 2022

The animal trypanosomiases and their chemotherapy: a review

por GIORDANI, FEDERICA, MORRISON, LIAM J., ROWAN, TIM G., DE KONING, HARRY P., BARRETT, MICHAEL P.
Publicado 2016

Multi-target mode of action of a Clerodane-type diterpenoid from Polyalthia longifolia targeting African trypanosomes

por Ebiloma, Godwin U., Katsoulis, Evangelos, Igoli, John O., Gray, Alexander I., De Koning, Harry P.
Publicado 2018

The individual components of commercial isometamidium do not possess stronger trypanocidal activity than the mixture, nor bypass isometamidium resistance

por Eze, Anthonius A., Igoli, John, Gray, Alexander I., Skellern, Graham G., De Koning, Harry P.
Publicado 2019

Chimerization at the AQP2–AQP3 locus is the genetic basis of melarsoprol–pentamidine cross-resistance in clinical Trypanosoma brucei gambiense isolates

por Graf, Fabrice E., Baker, Nicola, Munday, Jane C., de Koning, Harry P., Horn, David, Mäser, Pascal
Publicado 2015

Trypanocidal action of bisphosphonium salts through a mitochondrial target in bloodstream form Trypanosoma brucei

por Alkhaldi, Abdulsalam A.M., Martinek, Jan, Panicucci, Brian, Dardonville, Christophe, Zíková, Alena, de Koning, Harry P.
Publicado 2015

Differences in Transporters Rather than Drug Targets Are the Principal Determinants of the Different Innate Sensitivities of Trypanosoma congolense and Trypanozoon Subgenus Trypano...

por Ungogo, Marzuq A., Campagnaro, Gustavo D., Alghamdi, Ali H., Natto, Manal J., de Koning, Harry P.
Publicado 2022

Genotypic Status of the TbAT1/P2 Adenosine Transporter of Trypanosoma brucei gambiense Isolates from Northwestern Uganda following Melarsoprol Withdrawal

por Kazibwe, Anne J. N., Nerima, Barbara, de Koning, Harry P., Mäser, Pascal, Barrett, Michael P., Matovu, Enock
Publicado 2009

Instability of aquaglyceroporin (AQP) 2 contributes to drug resistance in Trypanosoma brucei

por Quintana, Juan F., Bueren-Calabuig, Juan, Zuccotto, Fabio, de Koning, Harry P., Horn, David, Field, Mark C.
Publicado 2020

The Strong Anti-Kinetoplastid Properties of Bee Propolis: Composition and Identification of the Active Agents and Their Biochemical Targets

por Ebiloma, Godwin U., Ichoron, Nahandoo, Siheri, Weam, Watson, David G., Igoli, John O., De Koning, Harry P.
Publicado 2020

Pharmacological Validation of Trypanosoma brucei Phosphodiesterases as Novel Drug Targets

por de Koning, Harry P., Gould, Matthew K., Sterk, Geert Jan, Tenor, Hermann, Kunz, Stefan, Luginbuehl, Edith, Seebeck, Thomas
Publicado 2012

In and out of the minor groove: interaction of an AT-rich DNA with the drug CD27

por Acosta-Reyes, Francisco J., Dardonville, Christophe, de Koning, Harry P., Natto, Manal, Subirana, Juan A., Campos, J. Lourdes
Publicado 2014