Epigenetic polypharmacology: from combination therapy to multitargeted drugs

por de Lera, Angel R., Ganesan, A.
Publicado 2016

Puzzling Out the Structure of Novofumigatamide: Total Synthesis of Constitutional Isomers. Part II

por García-Domínguez, Patricia, de Lera, Angel R.
Publicado 2022

Total Synthesis of the Proposed Structure of (−)-Novofumigatamide, Isomers Thereof, and Analogues. Part I

por García-Domínguez, Patricia, Lorenzo, Paula, Álvarez, Rosana, de Lera, Angel R.
Publicado 2022

Bispyrrolidinoindoline Epi(poly)thiodioxopiperazines (BPI-ETPs) and Simplified Mimetics: Structural Characterization, Bioactivities, and Total Synthesis †

por Martínez, Claudio, García-Domínguez, Patricia, Álvarez, Rosana, de Lera, Angel R.
Publicado 2022

Regulation of Hoxb4 induction after neurulation by somite signal and neural competence

por Amirthalingam, Gayana S, Howard, Sara, Alvarez, Susana, de Lera, Angel R, Itasaki, Nobue
Publicado 2009

Stereoselective Synthesis of Bisfuranoxide (Aurochrome, Auroxanthin) and Monofuranoxide (Equinenone 5′,8′-Epoxide) Carotenoids by Double Horner–Wadsworth–Emmons Reaction

por Rivas, Aurea, Castiñeira, Marta, Álvarez, Rosana, Vaz, Belén, de Lera, Angel R.
Publicado 2022

Human nutritional relevance and suggested nutritional guidelines for vitamin A5/X and provitamin A5/X

por Bohn, Torsten, Hellman-Regen, Julian, de Lera, Angel R., Böhm, Volker, Rühl, Ralph
Publicado 2023

Apo-14´-Carotenoic Acid Is a Novel Endogenous and Bioactive Apo-Carotenoid

por Aydemir, Gamze, Domínguez, Marta, de Lera, Angel R., Mihaly, Johanna, Törőcsik, Dániel, Rühl, Ralph
Publicado 2019

Multicomponent and multicatalytic asymmetric synthesis of furo[2,3-b]pyrrole derivatives: further insights into the mode of action of chiral phosphoric acid catalysts

por Cala, Lara, Villar, Pedro, de Lera, Ángel R., Fañanás, Francisco J., Álvarez, Rosana, Rodríguez, Félix
Publicado 2020

Evolution of the Role of RA and FGF Signals in the Control of Somitogenesis in Chordates

por Bertrand, Stéphanie, Aldea, Daniel, Oulion, Silvan, Subirana, Lucie, de Lera, Angel R., Somorjai, Ildiko, Escriva, Hector
Publicado 2015

Vitamin A5/X, a New Food to Lipid Hormone Concept for a Nutritional Ligand to Control RXR-Mediated Signaling

por Krężel, Wojciech, Rivas, Aurea, Szklenar, Monika, Ciancia, Marion, Alvarez, Rosana, de Lera, Angel R., Rühl, Ralph
Publicado 2021

Vitamin A5/X controls stress-adaptation and prevents depressive-like behaviors in a mouse model of chronic stress

por Krzyżosiak, Agnieszka, Podleśny-Drabiniok, Anna, Vaz, Belén, Alvarez, Rosana, Rühl, Ralph, de Lera, Angel R., Krężel, Wojciech
Publicado 2021

Synergistic Antitumoral Effect of Epigenetic Inhibitors and Gemcitabine in Pancreatic Cancer Cells

por Maietta, Immacolata, Martínez-Pérez, Amparo, Álvarez, Rosana, De Lera, Ángel R., González-Fernández, África, Simón-Vázquez, Rosana
Publicado 2022

Regulation of Retinoid-Mediated Signaling Involved in Skin Homeostasis by RAR and RXR Agonists/Antagonists in Mouse Skin

por Gericke, Janine, Ittensohn, Jan, Mihály, Johanna, Álvarez, Susana, Álvarez, Rosana, Töröcsik, Dániel, de Lera, Ángel R., Rühl, Ralph
Publicado 2013

Palladium-Catalyzed Aminocyclization–Coupling Cascades: Preparation of Dehydrotryptophan Derivatives and Computational Study

por Vaz, Belén, Martínez, Claudio, Cruz, Francisco, Denis, J. Gabriel, de Lera, Ángel R., Aurrecoechea, José M., Álvarez, Rosana
Publicado 2021

Distinct retinoic acid receptor (RAR) isotypes control differentiation of embryonal carcinoma cells to dopaminergic or striatopallidal medium spiny neurons

por Podleśny-Drabiniok, Anna, Sobska, Joanna, de Lera, Angel R., Gołembiowska, Krystyna, Kamińska, Katarzyna, Dollé, Pascal, Cebrat, Małgorzata, Krężel, Wojciech
Publicado 2017

Roles of retinoic acid and Tbx1/10 in pharyngeal segmentation: amphioxus and the ancestral chordate condition

por Koop, Demian, Chen, Jie, Theodosiou, Maria, Carvalho, João E, Alvarez, Susana, de Lera, Angel R, Holland, Linda Z, Schubert, Michael
Publicado 2014

Epigenetic modulator UVI5008 inhibits MRSA by interfering with bacterial gyrase

por Franci, Gianluigi, Folliero, Veronica, Cammarota, Marcella, Zannella, Carla, Sarno, Federica, Schiraldi, Chiara, de Lera, Angel R., Altucci, Lucia, Galdiero, Massimiliano
Publicado 2018

Lineage-specific duplication of amphioxus retinoic acid degrading enzymes (CYP26) resulted in sub-functionalization of patterning and homeostatic roles

por Carvalho, João E., Theodosiou, Maria, Chen, Jie, Chevret, Pascale, Alvarez, Susana, De Lera, Angel R., Laudet, Vincent, Croce, Jenifer C., Schubert, Michael
Publicado 2017

Probing a Polar Cluster in the Retinal Binding Pocket of Bacteriorhodopsin by a Chemical Design Approach

por Simón-Vázquez, Rosana, Domínguez, Marta, Lórenz-Fonfría, Víctor A., Álvarez, Susana, Bourdelande, José-Luís, de Lera, Ángel R., Padrós, Esteve, Perálvarez-Marín, Alex
Publicado 2012