pKa Modulation of the Acid/Base Catalyst within GH32 and GH68: A Role in Substrate/Inhibitor Specificity?

por Yuan, Shuguang, Le Roy, Katrien, Venken, Tom, Lammens, Willem, Van den Ende, Wim, De Maeyer, Marc
Publicado 2012

Mapping the Binding Interface between an HIV-1 Inhibiting Intrabody and the Viral Protein Rev

por Vercruysse, Thomas, Boons, Eline, Venken, Tom, Vanstreels, Els, Voet, Arnout, Steyaert, Jan, De Maeyer, Marc, Daelemans, Dirk
Publicado 2013

LRRK2 Kinase Activity Is Dependent on LRRK2 GTP Binding Capacity but Independent of LRRK2 GTP Binding

por Taymans, Jean-Marc, Vancraenenbroeck, Renée, Ollikainen, Petri, Beilina, Alexandra, Lobbestael, Evy, De Maeyer, Marc, Baekelandt, Veerle, Cookson, Mark R.
Publicado 2011

In silico, in vitro and cellular analysis with a kinome-wide inhibitor panel correlates cellular LRRK2 dephosphorylation to inhibitor activity on LRRK2

por Vancraenenbroeck, Renée, De Raeymaecker, Joren, Lobbestael, Evy, Gao, Fangye, De Maeyer, Marc, Voet, Arnout, Baekelandt, Veerle, Taymans, Jean-Marc
Publicado 2014

‘Drc’, a structurally novel ssDNA-binding transcription regulator of N4-related bacterial viruses

por Boon, Maarten, De Zitter, Elke, De Smet, Jeroen, Wagemans, Jeroen, Voet, Marleen, Pennemann, Friederike L, Schalck, Thomas, Kuznedelov, Konstantin, Severinov, Konstantin, Van Meervelt, Luc, De Maeyer, Marc, Lavigne, Rob
Publicado 2020

Biochemical Characterization of Highly Purified Leucine-Rich Repeat Kinases 1 and 2 Demonstrates Formation of Homodimers

por Civiero, Laura, Vancraenenbroeck, Renée, Belluzzi, Elisa, Beilina, Alexandra, Lobbestael, Evy, Reyniers, Lauran, Gao, Fangye, Micetic, Ivan, De Maeyer, Marc, Bubacco, Luigi, Baekelandt, Veerle, Cookson, Mark R., Greggio, Elisa, Taymans, Jean-Marc
Publicado 2012

Structural elucidation of a novel mechanism for the bacteriophage-based inhibition of the RNA degradosome

por Van den Bossche, An, Hardwick, Steven W, Ceyssens, Pieter-Jan, Hendrix, Hanne, Voet, Marleen, Dendooven, Tom, Bandyra, Katarzyna J, De Maeyer, Marc, Aertsen, Abram, Noben, Jean-Paul, Luisi, Ben F, Lavigne, Rob
Publicado 2016