Mammalian cell expression, purification, crystallization and microcrystal data collection of autotaxin/ENPP2, a secreted mammalian glycoprotein

por Hausmann, Jens, Christodoulou, Evangelos, Kasiem, Mobien, De Marco, Valeria, van Meeteren, Laurens A., Moolenaar, Wouter H., Axford, Danny, Owen, Robin L., Evans, Gwyndaf, Perrakis, Anastassis
Publicado 2010

Small Molecule Inhibitor Targeting CDT1/Geminin Protein Complex Promotes DNA Damage and Cell Death in Cancer Cells

por Karantzelis, Nikolaos, Petropoulos, Michalis, De Marco, Valeria, Egan, David A., Fish, Alexander, Christodoulou, Evangelos, Will, David W., Lewis, Joe D., Perrakis, Anastassis, Lygerou, Zoi, Taraviras, Stavros
Publicado 2022

Targeting Polycomb to Pericentric Heterochromatin in Embryonic Stem Cells Reveals a Role for H2AK119u1 in PRC2 Recruitment

por Cooper, Sarah, Dienstbier, Martin, Hassan, Raihann, Schermelleh, Lothar, Sharif, Jafar, Blackledge, Neil P., De Marco, Valeria, Elderkin, Sarah, Koseki, Haruhiko, Klose, Robert, Heger, Andreas, Brockdorff, Neil
Publicado 2014

A TPR domain–containing N-terminal module of MPS1 is required for its kinetochore localization by Aurora B

por Nijenhuis, Wilco, von Castelmur, Eleonore, Littler, Dene, De Marco, Valeria, Tromer, Eelco, Vleugel, Mathijs, van Osch, Maria H.J., Snel, Berend, Perrakis, Anastassis, Kops, Geert J.P.L.
Publicado 2013

Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2

por Justin, Neil, Zhang, Ying, Tarricone, Cataldo, Martin, Stephen R., Chen, Shuyang, Underwood, Elizabeth, De Marco, Valeria, Haire, Lesley F., Walker, Philip A., Reinberg, Danny, Wilson, Jon R., Gamblin, Steven J.
Publicado 2016