Naloxonazine, an Amastigote-Specific Compound, Affects Leishmania Parasites through Modulation of Host-Encoded Functions

por De Muylder, Géraldine, Vanhollebeke, Benoit, Caljon, Guy, Wolfe, Alan R., McKerrow, James, Dujardin, Jean-Claude
Publicado 2016

The Absence of C-5 DNA Methylation in Leishmania donovani Allows DNA Enrichment from Complex Samples

por Cuypers, Bart, Dumetz, Franck, Meysman, Pieter, Laukens, Kris, De Muylder, Géraldine, Dujardin, Jean-Claude, Domagalska, Malgorzata Anna
Publicado 2020

Importance of secondary screening with clinical isolates for anti-leishmania drug discovery

por Hefnawy, Aya, Cantizani, Juan, Peña, Imanol, Manzano, Pilar, Rijal, Suman, Dujardin, Jean-Claude, De Muylder, Geraldine, Martin, Julio
Publicado 2018

A Screen against Leishmania Intracellular Amastigotes: Comparison to a Promastigote Screen and Identification of a Host Cell-Specific Hit

por De Muylder, Geraldine, Ang, Kenny K. H., Chen, Steven, Arkin, Michelle R., Engel, Juan C., McKerrow, James H.
Publicado 2011

Hit-to-Lead Development of the Chamigrane Endoperoxide Merulin A for the Treatment of African Sleeping Sickness

por Navarro, Gabriel, Chokpaiboon, Supchar, De Muylder, Geraldine, Bray, Walter M., Nisam, Sean C., McKerrow, James H., Pudhom, Khanitha, Linington, Roger G.
Publicado 2012

The adaptive roles of aneuploidy and polyclonality in Leishmania in response to environmental stress

por Negreira, Gabriel H, de Groote, Robin, Van Giel, Dorien, Monsieurs, Pieter, Maes, Ilse, de Muylder, Geraldine, Van den Broeck, Frederik, Dujardin, Jean‐Claude, Domagalska, Malgorzata A
Publicado 2023

Macromolecular biosynthetic parameters and metabolic profile in different life stages of Leishmania braziliensis: Amastigotes as a functionally less active stage

por Jara, Marlene, Berg, Maya, Caljon, Guy, de Muylder, Geraldine, Cuypers, Bart, Castillo, Denis, Maes, Ilse, Orozco, María del Carmen, Vanaerschot, Manu, Dujardin, Jean-Claude, Arevalo, Jorge
Publicado 2017

Integrated genomic and metabolomic profiling of ISC1, an emerging Leishmania donovani population in the Indian subcontinent

por Cuypers, Bart, Berg, Maya, Imamura, Hideo, Dumetz, Franck, De Muylder, Géraldine, Domagalska, Malgorzata A., Rijal, Suman, Bhattarai, Narayan Raj, Maes, Ilse, Sanders, Mandy, Cotton, James A., Meysman, Pieter, Laukens, Kris, Dujardin, Jean-Claude
Publicado 2018

Targeting Ergosterol Biosynthesis in Leishmania donovani: Essentiality of Sterol 14alpha-demethylase

por McCall, Laura-Isobel, El Aroussi, Amale, Choi, Jun Yong, Vieira, Debora F., De Muylder, Geraldine, Johnston, Jonathan B., Chen, Steven, Kellar, Danielle, Siqueira-Neto, Jair L., Roush, William R., Podust, Larissa M., McKerrow, James H.
Publicado 2015

Genomic and Phenotypic Characterization of Experimentally Selected Resistant Leishmania donovani Reveals a Role for Dynamin-1-Like Protein in the Mechanism of Resistance to a Novel...

por Hefnawy, Aya, Negreira, Gabriel, Jara, Marlene, Cotton, James A., Maes, Ilse, D’Haenens, Erika, Imamura, Hideo, Cuypers, Bart, Monsieurs, Pieter, Mouchtoglou, Christina, De Winter, Hans, Pintelon, Isabel, Timmermans, Jean-Pierre, Berriman, Matt, Sanders, Mandy, Martin, Julio, de Muylder, Geraldine, Dujardin, Jean-Claude, Sterckx, Yann G.-J., Domagalska, Malgorzata Anna
Publicado 2022

A Trypanosoma brucei Kinesin Heavy Chain Promotes Parasite Growth by Triggering Host Arginase Activity

por De Muylder, Géraldine, Daulouède, Sylvie, Lecordier, Laurence, Uzureau, Pierrick, Morias, Yannick, Van Den Abbeele, Jan, Caljon, Guy, Hérin, Michel, Holzmuller, Philippe, Semballa, Silla, Courtois, Pierrette, Vanhamme, Luc, Stijlemans, Benoît, De Baetselier, Patrick, Barrett, Michael P., Barlow, Jillian L., McKenzie, Andrew N. J., Barron, Luke, Wynn, Thomas A., Beschin, Alain, Vincendeau, Philippe, Pays, Etienne
Publicado 2013

Evolutionary genomics of epidemic visceral leishmaniasis in the Indian subcontinent

por Imamura, Hideo, Downing, Tim, Van den Broeck, Frederik, Sanders, Mandy J, Rijal, Suman, Sundar, Shyam, Mannaert, An, Vanaerschot, Manu, Berg, Maya, De Muylder, Géraldine, Dumetz, Franck, Cuypers, Bart, Maes, Ilse, Domagalska, Malgorzata, Decuypere, Saskia, Rai, Keshav, Uranw, Surendra, Bhattarai, Narayan Raj, Khanal, Basudha, Prajapati, Vijay Kumar, Sharma, Smriti, Stark, Olivia, Schönian, Gabriele, De Koning, Harry P, Settimo, Luca, Vanhollebeke, Benoit, Roy, Syamal, Ostyn, Bart, Boelaert, Marleen, Maes, Louis, Berriman, Matthew, Dujardin, Jean-Claude, Cotton, James A
Publicado 2016

Hepatitis of unknown aetiology in children – epidemiological overview of cases reported in Europe, 1 January to 16 June 2022

por Romaní Vidal, Adriana, Vaughan, Aisling, Innocenti, Francesco, Colombe, Soledad, Nerlander, Lina, Rachwal, Natalia, Ciancio, Bruno Christian, Mougkou, Aikaterini, Carvalho, Carlos, Delgado, Enrique, Mook, Piers, de Muylder, Géraldine, Peeters, Michael, Tenev, Tencho, Golkocheva-Markova, Elitsa, Vorobieva Solholm Jensen, Veronika, Koch, Anders, Figoni, Julie, Brouard, Cécile, Nikolopoulou, Georgia, Zisouli, Anastasia, Murphy, Niamh, Broderick, Annemarie, Goldberg, Lital, Rich, Rivka, Hecht Sagie, Lior, Tosti, Maria Elena, Suligoi, Barbara, Joosten, Rosa, Pijnacker, Roan, Fjeldheim, Ingvild, Heen, Eli, Stępień, Małgorzata, Polański, Piotr, Tato Marinho, Rui, Vieira Martins, João, Varela, Carmen, Avellón, Ana, Andersson, Emmi, Jansson Mörk, Marie, Mandal, Sema, Watson, Conall, Coughlan, Laura, Chand, Meera, Neill, Claire, Bradley, Declan T, Li, Kathy, O’Leary, Maureen, McInnes, Neil, Williams, Christopher J, Moore, Catherine, Gjini, Ardiana, Duffell, Erika, Pebody, Richard
Publicado 2022