The developmental gene Chordin is amplified and expressed in human cancers

por Sosa, Eric, De Robertis, Edward M.
Publicado 2023

Point mutations in the tumor suppressor Smad4/DPC4 enhance its phosphorylation by GSK3 and reversibly inactivate TGF-β signaling

por Demagny, Hadrien, De Robertis, Edward M
Publicado 2015

Smad4/DPC4: A barrier against tumor progression driven by RTK/Ras/Erk and Wnt/GSK3 signaling

por Demagny, Hadrien, De Robertis, Edward M
Publicado 2015

Embryonic regeneration by relocalization of the Spemann organizer during twinning in Xenopus

por Moriyama, Yuki, De Robertis, Edward M.
Publicado 2018

Lysosomes are required for early dorsal signaling in the Xenopus embryo

por Tejeda-Muñoz, Nydia, De Robertis, Edward M.
Publicado 2022

Protocol for culturing and imaging of ectodermal cells from Xenopus

por Tejeda-Muñoz, Nydia, Monka, Julia, De Robertis, Edward M.
Publicado 2022

Canonical Wnt is inhibited by targeting one-carbon metabolism through methotrexate or methionine deprivation

por Albrecht, Lauren V., Bui, Maggie H., De Robertis, Edward M.
Publicado 2019

Drosophila Smad2 Opposes Mad Signaling during Wing Vein Development

por Sander, Veronika, Eivers, Edward, Choi, Renee H., De Robertis, Edward M.
Publicado 2010

Arginine methylation is required for canonical Wnt signaling and endolysosomal trafficking

por Albrecht, Lauren V., Ploper, Diego, Tejeda-Muñoz, Nydia, De Robertis, Edward M.
Publicado 2018

Wnt canonical pathway activates macropinocytosis and lysosomal degradation of extracellular proteins

por Tejeda-Muñoz, Nydia, Albrecht, Lauren V., Bui, Maggie H., De Robertis, Edward M.
Publicado 2019

Canonical Wnt signaling induces focal adhesion and Integrin beta-1 endocytosis

por Tejeda-Muñoz, Nydia, Morselli, Marco, Moriyama, Yuki, Sheladiya, Pooja, Pellegrini, Matteo, De Robertis, Edward M.
Publicado 2022

Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis

por Ding, Yi, Colozza, Gabriele, Sosa, Eric A., Moriyama, Yuki, Rundle, Samantha, Salwinski, Lukasz, De Robertis, Edward M.
Publicado 2018

Addition of exogenous diacylglycerol enhances Wnt/β-catenin signaling through stimulation of macropinocytosis

por Azbazdar, Yagmur, Tejeda-Munoz, Nydia, Monka, Julia C., Dayrit, Alex, Binder, Grace, Ozhan, Gunes, De Robertis, Edward M.
Publicado 2023

The PMA Phorbol Ester Tumor Promoter Increases Canonical Wnt Signaling Via Macropinocytosis

por Tejeda-Muñoz, Nydia, Azbazdar, Yagmur, Monka, Julia, Binder, Grace, Dayrit, Alex, Ayala, Raul, O’Brien, Neil, De Robertis, Edward M.
Publicado 2023

The PMA phorbol ester tumor promoter increases canonical Wnt signaling via macropinocytosis

por Tejeda-Munoz, Nydia, Azbazdar, Yagmur, Monka, Julia, Binder, Grace, Dayrit, Alex, Ayala, Raul, O'Brien, Neil, De Robertis, Edward M
Publicado 2023

Wnt-inducible Lrp6-APEX2 interacting proteins identify ESCRT machinery and Trk-fused gene as components of the Wnt signaling pathway

por Colozza, Gabriele, Jami-Alahmadi, Yasaman, Dsouza, Alyssa, Tejeda-Muñoz, Nydia, Albrecht, Lauren V., Sosa, Eric A., Wohlschlegel, James A., De Robertis, Edward M.
Publicado 2020

GSK3 Inhibits Macropinocytosis and Lysosomal Activity through the Wnt Destruction Complex Machinery

por Albrecht, Lauren V., Tejeda-Muñoz, Nydia, Bui, Maggie H., Cicchetto, Andrew C., Di Biagio, Daniele, Colozza, Gabriele, Schmid, Ernst, Piccolo, Stefano, Christofk, Heather R., De Robertis, Edward M.
Publicado 2020

The cytokine FAM3B/PANDER is an FGFR ligand that promotes posterior development in Xenopus

por Zhang, Fangfang, Zhu, Xuechen, Wang, Pan, He, Qing, Huang, Huimei, Zheng, Tianrui, Li, Yongyu, Jia, Hong, Xu, Linping, Zhao, Huaxiang, Colozza, Gabriele, Tao, Qinghua, De Robertis, Edward M., Ding, Yi
Publicado 2021