Selection of IgG Variants with Increased FcRn Binding Using Random and Directed Mutagenesis: Impact on Effector Functions

por Monnet, Céline, Jorieux, Sylvie, Urbain, Rémi, Fournier, Nathalie, Bouayadi, Khalil, De Romeuf, Christophe, Behrens, Christian K., Fontayne, Alexandre, Mondon, Philippe
Publicado 2015

Rise and Fall of an Anti-MUC1 Specific Antibody

por Thie, Holger, Toleikis, Lars, Li, Jiandong, von Wasielewski, Reinhard, Bastert, Gunther, Schirrmann, Thomas, Esteves, Isabel Tourais, Behrens, Christian K., Fournes, Bénédict, Fournier, Nathalie, de Romeuf, Christophe, Hust, Michael, Dübel, Stefan
Publicado 2011

Improved in vitro and in vivo activity against CD303-expressing targets of the chimeric 122A2 antibody selected for specific glycosylation pattern

por Fournier, Nathalie, Jacque, Emilie, Fontayne, Alexandre, Derache, Delphine, Dupont, Gilles, Verhaeghe, Lucie, Baptista, Linda, Dehenne, Aurélie, Dezetter, Anne-Sophie, Terrier, Aurélie, Longue, Alain, Pochet-Beghin, Virginie, Beghin, Cecile, Chtourou, Sami, de Romeuf, Christophe
Publicado 2018

Transgenic goats producing an improved version of cetuximab in milk

por Laible, Götz, Cole, Sally, Brophy, Brigid, Maclean, Paul, How Chen, Li, Pollock, Dan P., Cavacini, Lisa, Fournier, Nathalie, De Romeuf, Christophe, Masiello, Nicholas C., Gavin, William G., Wells, David N., Meade, Harry M.
Publicado 2020

Hyper-Enriched Anti-RSV Immunoglobulins Nasally Administered: A Promising Approach for Respiratory Syncytial Virus Prophylaxis

por Jacque, Emilie, Chottin, Claire, Laubreton, Daphné, Nogre, Michel, Ferret, Cécile, de Marcos, Sandrine, Baptista, Linda, Drajac, Carole, Mondon, Philippe, De Romeuf, Christophe, Rameix-Welti, Marie-Anne, Eléouët, Jean-François, Chtourou, Sami, Riffault, Sabine, Perret, Gérald, Descamps, Delphyne
Publicado 2021

The anti-tumor efficacy of 3C23K, a glyco-engineered humanized anti-MISRII antibody, in an ovarian cancer model is mainly mediated by engagement of immune effector cells

por Estupina, Pauline, Fontayne, Alexandre, Barret, Jean-Marc, Kersual, Nathalie, Dubreuil, Olivier, Le Blay, Marion, Pichard, Alexandre, Jarlier, Marta, Pugnière, Martine, Chauvin, Maëva, Chardès, Thierry, Pouget, Jean-Pierre, Deshayes, Emmanuel, Rossignol, Alexis, Abache, Toufik, de Romeuf, Christophe, Terrier, Aurélie, Verhaeghe, Lucie, Gaucher, Christine, Prost, Jean-François, Pèlegrin, André, Navarro-Teulon, Isabelle
Publicado 2017

The Dual Targeting of FcRn and FcγRs via Monomeric Fc Fragments Results in Strong Inhibition of IgG-Dependent Autoimmune Pathologies

por Monnet, Céline, Jacque, Emilie, de Romeuf, Christophe, Fontayne, Alexandre, Abache, Toufik, Fournier, Nathalie, Dupont, Gilles, Derache, Delphine, Engrand, Anais, Bauduin, Aurélie, Terrier, Aurélie, Seifert, Alexander, Beghin, Cécile, Longue, Alain, Masiello, Nicholas, Danino, Laetitia, Nogre, Michel, Raia, Anais, Dhainaut, Frederic, Fauconnier, Louis, Togbe, Dieudonnée, Reitinger, Carmen, Nimmerjahn, Falk, Stevens, Wil, Chtourou, Sami, Mondon, Philippe
Publicado 2021