Roles for the 8-Oxoguanine DNA Repair System in Protecting Telomeres From Oxidative Stress

por De Rosa, Mariarosaria, Johnson, Samuel A., Opresko, Patricia L.
Publicado 2021

OGG1 and MUTYH repair activities promote telomeric 8-oxoguanine induced cellular senescence

por De Rosa, Mariarosaria, Barnes, Ryan P., Nyalapatla, Prasanth R., Wipf, Peter, Opresko, Patricia L.
Publicado 2023

Methylation of the Suppressor Gene p16INK4a: Mechanism and Consequences

por Tramontano, Alfonso, Boffo, Francesca Ludovica, Russo, Giusi, De Rosa, Mariarosaria, Iodice, Ilaria, Pezone, Antonio
Publicado 2020

Designer Fluorescent Adenines Enable Real-Time Monitoring of MUTYH Activity

por Zhu, Ru-Yi, Majumdar, Chandrima, Khuu, Cindy, De Rosa, Mariarosaria, Opresko, Patricia L., David, Sheila S., Kool, Eric T.
Publicado 2020

RNA Stabilizes Transcription-Dependent Chromatin Loops Induced By Nuclear Hormones

por Pezone, Antonio, Zuchegna, Candida, Tramontano, Alfonso, Romano, Antonella, Russo, Giusi, de Rosa, Mariarosaria, Vinciguerra, Maria, Porcellini, Antonio, Gottesman, Max E., Avvedimento, Enrico Vittorio
Publicado 2019

Telomeric 8-oxo-guanine drives rapid premature senescence in the absence of telomere shortening

por Barnes, Ryan P., de Rosa, Mariarosaria, Thosar, Sanjana A., Detwiler, Ariana C., Roginskaya, Vera, Van Houten, Bennett, Bruchez, Marcel P., Stewart-Ornstein, Jacob, Opresko, Patricia L.
Publicado 2022

Targeted DNA oxidation by LSD1–SMAD2/3 primes TGF-β1/ EMT genes for activation or repression

por Pezone, Antonio, Taddei, Maria Letizia, Tramontano, Alfonso, Dolcini, Jacopo, Boffo, Francesca Ludovica, De Rosa, Mariarosaria, Parri, Matteo, Stinziani, Stefano, Comito, Giuseppina, Porcellini, Antonio, Raugei, Giovanni, Gackowski, Daniel, Zarakowska, Ewelina, Olinski, Ryszard, Gabrielli, Armando, Chiarugi, Paola, Avvedimento, Enrico Vittorio
Publicado 2020