Differential tissue specific, temporal and spatial expression patterns of the Aggrecan gene is modulated by independent enhancer elements

por Li, Ian M. H., Liu, Ke, Neal, Alice, Clegg, Peter D., De Val, Sarah, Bou-Gharios, George
Publicado 2018

ETS factors are required but not sufficient for specific patterns of enhancer activity in different endothelial subtypes

por Neal, Alice, Nornes, Svanhild, Louphrasitthiphol, Pakavarin, Sacilotto, Natalia, Preston, Mark D., Fleisinger, Lucija, Payne, Sophie, De Val, Sarah
Publicado 2021

Multiple enhancer regions govern the transcription of CCN2 during embryonic development

por Frost, Stephanie L., Liu, Ke, Li, Ian M. H., Poulet, Blandine, Comerford, Eithne, De Val, Sarah, Bou-Gharios, George
Publicado 2017

Regulatory pathways governing murine coronary vessel formation are dysregulated in the injured adult heart

por Payne, Sophie, Gunadasa-Rohling, Mala, Neal, Alice, Redpath, Andia N., Patel, Jyoti, Chouliaras, Kira M., Ratnayaka, Indrika, Smart, Nicola, De Val, Sarah
Publicado 2019

Krüppel‐Like Factors Orchestrate Endothelial Gene Expression Through Redundant and Non‐Redundant Enhancer Networks

por Sweet, David R., Padmanabhan, Roshan, Liao, Xudong, Dashora, Himanshu R., Tang, Xinmiao, Nayak, Lalitha, Jain, Rajan, De Val, Sarah, Vinayachandran, Vinesh, Jain, Mukesh K.
Publicado 2023

An Intronic Flk1 Enhancer Directs Arterial-Specific Expression via RBPJ-Mediated Venous Repression

por Becker, Philipp W., Sacilotto, Natalia, Nornes, Svanhild, Neal, Alice, Thomas, Max O., Liu, Ke, Preece, Chris, Ratnayaka, Indrika, Davies, Benjamin, Bou-Gharios, George, De Val, Sarah
Publicado 2016

AdPLA ablation increases lipolysis and prevents obesity induced by high fat feeding or leptin deficiency

por Jaworski, Kathy, Ahmadian, Maryam, Duncan, Robin E., Sarkadi-Nagy, Eszter, Varady, Krista A., Hellerstein, Marc K., Lee, Hui-Young, Samuel, Varman T., Shulman, Gerald I., Kim, Kee-Hong, de Val, Sarah, Kang, Chulho, Sul, Hei Sook
Publicado 2009

Analysis of Placental Arteriovenous Formation Reveals New Insights Into Embryos With Congenital Heart Defects

por Kalisch-Smith, Jacinta I., Morris, Emily C., Strevens, Mary A. A., Redpath, Andia N., Klaourakis, Kostantinos, Szumska, Dorota, Outhwaite, Jennifer E., Sun, Xin, Vieira, Joaquim Miguel, Smart, Nicola, De Val, Sarah, Riley, Paul R., Sparrow, Duncan B.
Publicado 2022

Venous identity requires BMP signalling through ALK3

por Neal, Alice, Nornes, Svanhild, Payne, Sophie, Wallace, Marsha D., Fritzsche, Martin, Louphrasitthiphol, Pakavarin, Wilkinson, Robert N., Chouliaras, Kira M., Liu, Ke, Plant, Karen, Sholapurkar, Radhika, Ratnayaka, Indrika, Herzog, Wiebke, Bond, Gareth, Chico, Tim, Bou-Gharios, George, De Val, Sarah
Publicado 2019

MEF2 transcription factors are key regulators of sprouting angiogenesis

por Sacilotto, Natalia, Chouliaras, Kira M., Nikitenko, Leonid L., Lu, Yao Wei, Fritzsche, Martin, Wallace, Marsha D., Nornes, Svanhild, García-Moreno, Fernando, Payne, Sophie, Bridges, Esther, Liu, Ke, Biggs, Daniel, Ratnayaka, Indrika, Herbert, Shane P., Molnár, Zoltán, Harris, Adrian L., Davies, Benjamin, Bond, Gareth L., Bou-Gharios, George, Schwarz, John J., De Val, Sarah
Publicado 2016

Corrigendum: MEF2 transcription factors are key regulators of sprouting angiogenesis

por Sacilotto, Natalia, Chouliaras, Kira M., Nikitenko, Leonid L., Lu, Yao Wei, Fritzsche, Martin, Wallace, Marsha D., Nornes, Svanhild, García-Moreno, Fernando, Payne, Sophie, Bridges, Esther, Liu, Ke, Biggs, Daniel, Ratnayaka, Indrika, Herbert, Shane P., Molnár, Zoltán, Harris, Adrian L., Davies, Benjamin, Bond, Gareth L., Bou-Gharios, George, Schwarz, John J., De Val, Sarah
Publicado 2022

Maternal iron deficiency perturbs embryonic cardiovascular development in mice

por Kalisch-Smith, Jacinta I., Ved, Nikita, Szumska, Dorota, Munro, Jacob, Troup, Michael, Harris, Shelley E., Rodriguez-Caro, Helena, Jacquemot, Aimée, Miller, Jack J., Stuart, Eleanor M., Wolna, Magda, Hardman, Emily, Prin, Fabrice, Lana-Elola, Eva, Aoidi, Rifdat, Fisher, Elizabeth M. C., Tybulewicz, Victor L. J., Mohun, Timothy J., Lakhal-Littleton, Samira, De Val, Sarah, Giannoulatou, Eleni, Sparrow, Duncan B.
Publicado 2021

JAG1-NOTCH4 mechanosensing drives atherosclerosis

por Souilhol, Celine, Tardajos Ayllon, Blanca, Li, Xiuying, Diagbouga, Mannekomba R., Zhou, Ziqi, Canham, Lindsay, Roddie, Hannah, Pirri, Daniela, Chambers, Emily V., Dunning, Mark J., Ariaans, Mark, Li, Jin, Fang, Yun, Jørgensen, Helle F., Simons, Michael, Krams, Rob, Waltenberger, Johannes, Fragiadaki, Maria, Ridger, Victoria, De Val, Sarah, Francis, Sheila E., Chico, Timothy JA, Serbanovic-Canic, Jovana, Evans, Paul C.
Publicado 2022

Correction: Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice

por Overman, Jeroen, Fontaine, Frank, Moustaqil, Mehdi, Mittal, Deepak, Sierecki, Emma, Sacilotto, Natalia, Zuegg, Johannes, Robertson, Avril AB, Holmes, Kelly, Salim, Angela A, Mamidyala, Sreeman, Butler, Mark S, Robinson, Ashley S, Lesieur, Emmanuelle, Johnston, Wayne, Alexandrov, Kirill, Black, Brian L, Hogan, Benjamin M, De Val, Sarah, Capon, Robert J, Carroll, Jason S, Bailey, Timothy L, Koopman, Peter, Jauch, Ralf, Cooper, Matthew A, Gambin, Yann, Francois, Mathias
Publicado 2023

Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice

por Overman, Jeroen, Fontaine, Frank, Moustaqil, Mehdi, Mittal, Deepak, Sierecki, Emma, Sacilotto, Natalia, Zuegg, Johannes, Robertson, Avril AB, Holmes, Kelly, Salim, Angela A, Mamidyala, Sreeman, Butler, Mark S, Robinson, Ashley S, Lesieur, Emmanuelle, Johnston, Wayne, Alexandrov, Kirill, Black, Brian L, Hogan, Benjamin M, De Val, Sarah, Capon, Robert J, Carroll, Jason S, Bailey, Timothy L, Koopman, Peter, Jauch, Ralf, Cooper, Matthew A, Gambin, Yann, Francois, Mathias
Publicado 2017