The Multifaceted Role of Regulatory T Cells in Breast Cancer

por Kos, Kevin, de Visser, Karin E.
Publicado 2021

Exploiting the Immunomodulatory Properties of Chemotherapeutic Drugs to Improve the Success of Cancer Immunotherapy

por Kersten, Kelly, Salvagno, Camilla, de Visser, Karin E.
Publicado 2015

Immune regulation of metastasis: mechanistic insights and therapeutic opportunities

por Blomberg, Olga S., Spagnuolo, Lorenzo, de Visser, Karin E.
Publicado 2018

Genetically engineered mouse models in oncology research and cancer medicine

por Kersten, Kelly, de Visser, Karin E, van Miltenburg, Martine H, Jonkers, Jos
Publicado 2016

Transcriptional Signature Derived from Murine Tumor-Associated Macrophages Correlates with Poor Outcome in Breast Cancer Patients

por Tuit, Sander, Salvagno, Camilla, Kapellos, Theodore S., Hau, Cheei-Sing, Seep, Lea, Oestreich, Marie, Klee, Kathrin, de Visser, Karin E., Ulas, Thomas, Schultze, Joachim L.
Publicado 2019

hMRP8-ATTAC Mice: A New Model for Conditional and Reversible Neutrophil Ablation

por Duits, Danique E. M., Salvagno, Camilla, Raeven, Elisabeth A. M., Vrijland, Kim, Stip, Marjolein C., Hau, Cheei-Sing, Kaldenbach, Daphne, de Visser, Karin E.
Publicado 2022

Transformed Canine and Murine Mesenchymal Stem Cells as a Model for Sarcoma with Complex Genomics

por Franceschini, Natasja, Verbruggen, Bas, Tryfonidou, Marianna A., Kruisselbrink, Alwine B., Baelde, Hans, de Visser, Karin E., Szuhai, Karoly, Cleton-Jansen, Anne-Marie, Bovée, Judith V. M. G.
Publicado 2021

IL17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis

por Coffelt, Seth B., Kersten, Kelly, Doornebal, Chris W., Weiden, Jorieke, Vrijland, Kim, Hau, Cheei-Sing, Verstegen, Niels J.M., Ciampricotti, Metamia, Hawinkels, Lukas J.A.C., Jonkers, Jos, de Visser, Karin E.
Publicado 2015

The adaptive immune system promotes initiation of prostate carcinogenesis in a human c-Myc transgenic mouse model

por Melis, Monique H.M., Nevedomskaya, Ekaterina, van Burgsteden, Johan, Cioni, Bianca, van Zeeburg, Hester J.T., Song, Ji-Ying, Zevenhoven, John, Hawinkels, Lukas J.A.C, de Visser, Karin E., Bergman, Andries M.
Publicado 2017

Pro-mutagenic effects of the gut microbiota in a Lynch syndrome mouse model

por Pieters, Wietske, Hugenholtz, Floor, Kos, Kevin, Cammeraat, Maxime, Moliej, Teddy C., Kaldenbach, Daphne, Klarenbeek, Sjoerd, Davids, Mark, Drost, Lisa, de Konink, Charlotte, Delzenne-Goette, Elly, de Visser, Karin E., te Riele, Hein
Publicado 2022

Tumor-associated macrophages promote intratumoral conversion of conventional CD4(+) T cells into regulatory T cells via PD-1 signalling

por Kos, Kevin, Salvagno, Camilla, Wellenstein, Max D., Aslam, Muhammad A., Meijer, Denize A., Hau, Cheei-Sing, Vrijland, Kim, Kaldenbach, Daphne, Raeven, Elisabeth A.M., Schmittnaegel, Martina, Ries, Carola H., de Visser, Karin E.
Publicado 2022

Radiolabeled Monoclonal Antibody Against Colony-Stimulating Factor 1 Receptor Specifically Distributes to the Spleen and Liver in Immunocompetent Mice

por Waaijer, Stijn J. H., Suurs, Frans V., Hau, Cheei-Sing, Vrijland, Kim, de Visser, Karin E., de Groot, Derk Jan A., de Vries, Elisabeth G. E., Lub-de Hooge, Marjolijn N., Schröder, Carolina P.
Publicado 2021

A comprehensive analysis of prognostic signatures reveals the high predictive capacity of the Proliferation, Immune response and RNA splicing modules in breast cancer

por Reyal, Fabien, van Vliet, Martin H, Armstrong, Nicola J, Horlings, Hugo M, de Visser, Karin E, Kok, Marlen, Teschendorff, Andrew E, Mook, Stella, van 't Veer, Laura, Caldas, Carlos, Salmon, Remy J, Vijver, Marc J van de, Wessels, Lodewyk FA
Publicado 2008

Mammary tumor-derived CCL2 enhances pro-metastatic systemic inflammation through upregulation of IL1β in tumor-associated macrophages

por Kersten, Kelly, Coffelt, Seth B., Hoogstraat, Marlous, Verstegen, Niels J.M., Vrijland, Kim, Ciampricotti, Metamia, Doornebal, Chris W., Hau, Cheei-Sing, Wellenstein, Max D., Salvagno, Camilla, Doshi, Parul, Lips, Esther H., Wessels, Lodewyk F.A., de Visser, Karin E.
Publicado 2017

Neoadjuvant immune checkpoint blockade triggers persistent and systemic T(reg) activation which blunts therapeutic efficacy against metastatic spread of breast tumors

por Blomberg, Olga S., Kos, Kevin, Spagnuolo, Lorenzo, Isaeva, Olga I., Garner, Hannah, Wellenstein, Max D., Bakker, Noor, Duits, Danique E.M., Kersten, Kelly, Klarenbeek, Sjoerd, Hau, Cheei-Sing, Kaldenbach, Daphne, Raeven, Elisabeth A.M., Vrijland, Kim, Kok, Marleen, de Visser, Karin E.
Publicado 2023

Response of metastatic mouse invasive lobular carcinoma to mTOR inhibition is partly mediated by the adaptive immune system

por Klarenbeek, Sjoerd, Doornebal, Chris W., Kas, Sjors M., Bonzanni, Nicola, Bhin, Jinhyuk, Braumuller, Tanya M., van der Heijden, Ingrid, Opdam, Mark, Schouten, Philip C., Kersten, Kelly, de Bruijn, Roebi, Zingg, Daniel, Yemelyanenko, Julia, Wessels, Lodewyk F.A., de Visser, Karin E., Jonkers, Jos
Publicado 2020

Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon response

por Salvagno, Camilla, Ciampricotti, Metamia, Tuit, Sander, Hau, Cheei-Sing, van Weverwijk, Antoinette, Coffelt, Seth B., Kersten, Kelly, Vrijland, Kim, Kos, Kevin, Ulas, Thomas, Song, Ji-Ying, Ooi, Chia-Huey, Rüttinger, Dominik, Cassier, Philippe A., Jonkers, Jos, Schultze, Joachim L., Ries, Carola H., de Visser, Karin E.
Publicado 2019

HPV-16 E6/E7 DNA tattoo vaccination using genetically optimized vaccines elicit clinical and immunological responses in patients with usual vulvar intraepithelial neoplasia (uVIN):...

por Bakker, Noor Alida Maria, Rotman, Jossie, van Beurden, Marc, Zijlmans, Henry J MAA, van Ruiten, Maartje, Samuels, Sanne, Nuijen, Bastiaan, Beijnen, Jos, De Visser, Karin, Haanen, John, Schumacher, Ton, de Gruijl, Tanja D, Jordanova, Ekaterina S, Kenter, Gemma G, van den Berg, Joost H, van Trommel, Nienke E
Publicado 2021

Poor Outcome in Postpartum Breast Cancer Patients Is Associated with Distinct Molecular and Immunologic Features

por Lefrère, Hanne, Moore, Kat, Floris, Giuseppe, Sanders, Joyce, Seignette, Iris M., Bismeijer, Tycho, Peters, Dennis, Broeks, Annegien, Hooijberg, Erik, Van Calsteren, Kristel, Neven, Patrick, Warner, Ellen, Peccatori, Fedro Alessandro, Loibl, Sibylle, Maggen, Charlotte, Han, Sileny N., Jerzak, Katarzyna J., Annibali, Daniela, Lambrechts, Diether, de Visser, Karin E., Wessels, Lodewyk, Lenaerts, Liesbeth, Amant, Frédéric
Publicado 2023

Loss of p53 triggers Wnt-dependent systemic inflammation to drive breast cancer metastasis

por Wellenstein, Max D., Coffelt, Seth B., Duits, Danique E.M., van Miltenburg, Martine H., Slagter, Maarten, de Rink, Iris, Henneman, Linda, Kas, Sjors M., Prekovic, Stefan, Hau, Cheei-Sing, Vrijland, Kim, Drenth, Anne Paulien, de Korte-Grimmerink, Renske, Schut, Eva, van der Heijden, Ingrid, Zwart, Wilbert, Wessels, Lodewyk F.A., Schumacher, Ton N., Jonkers, Jos, de Visser, Karin E.
Publicado 2019