Targeting Cullin-RING E3 Ubiquitin Ligase 4 by Small Molecule Modulators

por Wu, Kenneth, Hopkins, Benjamin D., Sanchez, Roberto, DeVita, Robert J., Pan, Zhen-Qiang
Publicado 2021

Human Beta Cell Regenerative Drug Therapy for Diabetes: Past Achievements and Future Challenges

por Wang, Peng, Karakose, Esra, Choleva, Lauryn, Kumar, Kunal, DeVita, Robert J., Garcia-Ocaña, Adolfo, Stewart, Andrew F.
Publicado 2021

A case of hyperlysinemia identified by urine newborn screening

por Yeganeh, Mehdi, Auray‐Blais, Christiane, Maranda, Bruno, Sabovic, Amanda, DeVita, Robert J., Lazarus, Michael B., Houten, Sander M.
Publicado 2023

Discovery and characterization of small-molecule inhibitors of NLRP3 and NLRC4 inflammasomes

por Sebastian-Valverde, Maria, Wu, Henry, Al Rahim, Md, Sanchez, Roberto, Kumar, Kunal, De Vita, Robert J., Pasinetti, Giulio Maria
Publicado 2021

Structure–Activity Relationships and Biological Evaluation of 7-Substituted Harmine Analogs for Human β-Cell Proliferation

por Kumar, Kunal, Wang, Peng, A. Swartz, Ethan, Khamrui, Susmita, Secor, Cody, B. Lazarus, Michael, Sanchez, Roberto, F. Stewart, Andrew, DeVita, Robert J.
Publicado 2020

Small Molecule Inhibition of Ligand-Stimulated RAGE-DIAPH1 Signal Transduction

por Manigrasso, Michaele B., Pan, Jinhong, Rai, Vivek, Zhang, Jinghua, Reverdatto, Sergey, Quadri, Nosirudeen, DeVita, Robert J., Ramasamy, Ravichandran, Shekhtman, Alexander, Schmidt, Ann Marie
Publicado 2016

Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure

por Kho, Changwon, Lee, Ahyoung, Jeong, Dongtak, Oh, Jae Gyun, Gorski, Przemek A., Fish, Kenneth, Sanchez, Roberto, DeVita, Robert J., Christensen, Geir, Dahl, Russell, Hajjar, Roger J.
Publicado 2015

Characterization and structure of the human lysine-2-oxoglutarate reductase domain, a novel therapeutic target for treatment of glutaric aciduria type 1

por Leandro, João, Khamrui, Susmita, Suebsuwong, Chalada, Chen, Peng-Jen, Secor, Cody, Dodatko, Tetyana, Yu, Chunli, Sanchez, Roberto, DeVita, Robert J., Houten, Sander M., Lazarus, Michael B.
Publicado 2022

Inhibitors of cullin-RING E3 ubiquitin ligase 4 with antitumor potential

por Wu, Kenneth, Huynh, Khoi Q., Lu, Iris, Moustakim, Moses, Miao, Haibin, Yu, Clinton, Haeusgen, Matthew J., Hopkins, Benjamin D., Huang, Lan, Zheng, Ning, Sanchez, Roberto, DeVita, Robert J., Pan, Zhen-Qiang
Publicado 2021

Identification and Characterization of Sebaceous Gland Atrophy-Sparing DGAT1 Inhibitors

por Muise, Eric S., Zhu, Yonghua, Verras, Andreas, Karanam, Bindhu V., Gorski, Judith, Weingarth, Drew, Lin, Hua V., Hwa, Joyce, Thompson, John R., Hu, Guanghui, Liu, Jian, He, Shuwen, DeVita, Robert J., Shen, Dong-Ming, Pinto, Shirly
Publicado 2014