Control over Imidazoquinoline Immune Stimulation by pH-Degradable Poly(norbornene) Nanogels

por Kockelmann, Johannes, Stickdorn, Judith, Kasmi, Sabah, De Vrieze, Jana, Pieszka, Michaela, Ng, David Yuen W., David, Sunil A., De Geest, Bruno G., Nuhn, Lutz
Publicado 2020

Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Modified Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine

por Jangra, Sonia, De Vrieze, Jana, Choi, Angela, Rathnasinghe, Raveen, Laghlali, Gabriel, Uvyn, Annemiek, Van Herck, Simon, Nuhn, Lutz, Deswarte, Kim, Zhong, Zifu, Sanders, Niek, Lienenklaus, Stefan, David, Sunil, Strohmeier, Shirin, Amanat, Fatima, Krammer, Florian, Hammad, Hamida, Lambrecht, Bart N., Coughlan, Lynda, García-Sastre, Adolfo, De Geest, Bruno G., Schotsaert, Michael
Publicado 2020

The N501Y mutation in SARS-CoV-2 spike leads to morbidity in obese and aged mice and is neutralized by convalescent and post-vaccination human sera

por Rathnasinghe, Raveen, Jangra, Sonia, Cupic, Anastasija, Martínez-Romero, Carles, Mulder, Lubbertus C.F., Kehrer, Thomas, Yildiz, Soner, Choi, Angela, Mena, Ignacio, De Vrieze, Jana, Aslam, Sadaf, Stadlbauer, Daniel, Meekins, David A., McDowell, Chester D., Balaraman, Velmurugan, Richt, Juergen A., De Geest, Bruno G., Miorin, Lisa, Krammer, Florian, Simon, Viviana, García-Sastre, Adolfo, Schotsaert, Michael
Publicado 2021

Squaric Ester-Based, pH-Degradable Nanogels: Modular Nanocarriers for Safe, Systemic Administration of Toll-like Receptor 7/8 Agonistic Immune Modulators

por Huppertsberg, Anne, Kaps, Leonard, Zhong, Zifu, Schmitt, Sascha, Stickdorn, Judith, Deswarte, Kim, Combes, Francis, Czysch, Christian, De Vrieze, Jana, Kasmi, Sabah, Choteschovsky, Niklas, Klefenz, Adrian, Medina-Montano, Carolina, Winterwerber, Pia, Chen, Chaojian, Bros, Matthias, Lienenklaus, Stefan, Sanders, Niek N., Koynov, Kaloian, Schuppan, Detlef, Lambrecht, Bart N., David, Sunil A., De Geest, Bruno G., Nuhn, Lutz
Publicado 2021

Characterization of SARS-CoV-2 Spike mutations important for infection of mice and escape from human immune sera

por Rathnasinghe, Raveen, Jangra, Sonia, Ye, Chengjin, Cupic, Anastasija, Singh, Gagandeep, Martínez-Romero, Carles, Mulder, Lubbertus C. F., Kehrer, Thomas, Yildiz, Soner, Choi, Angela, Yeung, Stephen T., Mena, Ignacio, Gillespie, Virginia, De Vrieze, Jana, Aslam, Sadaf, Stadlbauer, Daniel, Meekins, David A., McDowell, Chester D., Balaraman, Velmurugan, Corley, Michael J., Richt, Juergen A., De Geest, Bruno G., Miorin, Lisa, Krammer, Florian, Martinez-Sobrido, Luis, Simon, Viviana, García-Sastre, Adolfo, Schotsaert, Michael
Publicado 2022