One-step CRISPR-Cas9-mediated knockout of native TCRαβ genes in human T cells using RNA electroporation

por Flumens, Donovan, Campillo-Davo, Diana, Janssens, Ibo, Roex, Gils, De Waele, Jorrit, Anguille, Sébastien, Lion, Eva
Publicado 2023

The Right Partner in Crime: Unlocking the Potential of the Anti-EGFR Antibody Cetuximab via Combination With Natural Killer Cell Chartering Immunotherapeutic Strategies

por Baysal, Hasan, De Pauw, Ines, Zaryouh, Hannah, Peeters, Marc, Vermorken, Jan Baptist, Lardon, Filip, De Waele, Jorrit, Wouters, An
Publicado 2021

Targeting the PD-1 Axis with Pembrolizumab for Recurrent or Metastatic Cancer of the Uterine Cervix: A Brief Update

por Verhoeven, Yannick, Quatannens, Delphine, Trinh, Xuan Bich, Wouters, An, Smits, Evelien L.J., Lardon, Filip, De Waele, Jorrit, van Dam, Peter A.
Publicado 2021

Immuno-PET Molecular Imaging of RANKL in Cancer

por Dewulf, Jonatan, Vangestel, Christel, Verhoeven, Yannick, De Waele, Jorrit, Zwaenepoel, Karen, van Dam, Peter A., Elvas, Filipe, Van den Wyngaert, Tim
Publicado 2021

A systematic review on poly(I:C) and poly-ICLC in glioblastoma: adjuvants coordinating the unlocking of immunotherapy

por De Waele, Jorrit, Verhezen, Tias, van der Heijden, Sanne, Berneman, Zwi N., Peeters, Marc, Lardon, Filip, Wouters, An, Smits, Evelien L. J. M.
Publicado 2021

Hypoxia-Induced Cisplatin Resistance in Non-Small Cell Lung Cancer Cells Is Mediated by HIF-1α and Mutant p53 and Can Be Overcome by Induction of Oxidative Stress

por Deben, Christophe, Deschoolmeester, Vanessa, De Waele, Jorrit, Jacobs, Julie, Van den Bossche, Jolien, Wouters, An, Peeters, Marc, Rolfo, Christian, Smits, Evelien, Lardon, Filip, Pauwels, Patrick
Publicado 2018

Cetuximab-induced natural killer cell cytotoxicity in head and neck squamous cell carcinoma cell lines: investigation of the role of cetuximab sensitivity and HPV status

por Baysal, Hasan, De Pauw, Ines, Zaryouh, Hannah, De Waele, Jorrit, Peeters, Marc, Pauwels, Patrick, Vermorken, Jan Baptist, Smits, Evelien, Lardon, Filip, Jacobs, Julie, Wouters, An
Publicado 2020

Building a Bridge between Chemotherapy and Immunotherapy in Malignant Pleural Mesothelioma: Investigating the Effect of Chemotherapy on Immune Checkpoint Expression

por Marcq, Elly, Van Audenaerde, Jonas RM, De Waele, Jorrit, Jacobs, Julie, Van Loenhout, Jinthe, Cavents, Glenn, Pauwels, Patrick, van Meerbeeck, Jan P, Smits, Evelien LJ
Publicado 2019

The Search for an Interesting Partner to Combine with PD-L1 Blockade in Mesothelioma: Focus on TIM-3 and LAG-3

por Marcq, Elly, Van Audenaerde, Jonas R. M., De Waele, Jorrit, Merlin, Céline, Pauwels, Patrick, van Meerbeeck, Jan P., Fisher, Scott A., Smits, Evelien L. J.
Publicado 2021

The CD70-CD27 axis in oncology: the new kids on the block

por Flieswasser, Tal, Van den Eynde, Astrid, Van Audenaerde, Jonas, De Waele, Jorrit, Lardon, Filip, Riether, Carsten, de Haard, Hans, Smits, Evelien, Pauwels, Patrick, Jacobs, Julie
Publicado 2022

Clinically Relevant Chemotherapeutics Have the Ability to Induce Immunogenic Cell Death in Non-Small Cell Lung Cancer

por Flieswasser, Tal, Van Loenhout, Jinthe, Freire Boullosa, Laurie, Van den Eynde, Astrid, De Waele, Jorrit, Van Audenaerde, Jonas, Lardon, Filip, Smits, Evelien, Pauwels, Patrick, Jacobs, Julie
Publicado 2020

Auranofin and Cold Atmospheric Plasma Synergize to Trigger Distinct Cell Death Mechanisms and Immunogenic Responses in Glioblastoma

por Van Loenhout, Jinthe, Freire Boullosa, Laurie, Quatannens, Delphine, De Waele, Jorrit, Merlin, Céline, Lambrechts, Hilde, Lau, Ho Wa, Hermans, Christophe, Lin, Abraham, Lardon, Filip, Peeters, Marc, Bogaerts, Annemie, Smits, Evelien, Deben, Christophe
Publicado 2021

Auranofin reveals therapeutic anticancer potential by triggering distinct molecular cell death mechanisms and innate immunity in mutant p53 non-small cell lung cancer

por Freire Boullosa, Laurie, Van Loenhout, Jinthe, Flieswasser, Tal, De Waele, Jorrit, Hermans, Christophe, Lambrechts, Hilde, Cuypers, Bart, Laukens, Kris, Bartholomeus, Esther, Siozopoulou, Vasiliki, De Vos, Winnok H., Peeters, Marc, Smits, Evelien L.J., Deben, Christophe
Publicado 2021

The prognostic impact of the immune signature in head and neck squamous cell carcinoma

por Baysal, Hasan, Siozopoulou, Vasiliki, Zaryouh, Hannah, Hermans, Christophe, Lau, Ho Wa, Lambrechts, Hilde, Fransen, Erik, De Pauw, Ines, Jacobs, Julie, Peeters, Marc, Pauwels, Patrick, Vermorken, Jan Baptist, Smits, Evelien, Lardon, Filip, De Waele, Jorrit, Wouters, An
Publicado 2022

Cold Atmospheric Plasma-Treated PBS Eliminates Immunosuppressive Pancreatic Stellate Cells and Induces Immunogenic Cell Death of Pancreatic Cancer Cells

por Van Loenhout, Jinthe, Flieswasser, Tal, Freire Boullosa, Laurie, De Waele, Jorrit, Van Audenaerde, Jonas, Marcq, Elly, Jacobs, Julie, Lin, Abraham, Lion, Eva, Dewitte, Heleen, Peeters, Marc, Dewilde, Sylvia, Lardon, Filip, Bogaerts, Annemie, Deben, Christophe, Smits, Evelien
Publicado 2019

Interleukin-15 stimulates natural killer cell-mediated killing of both human pancreatic cancer and stellate cells

por Van Audenaerde, Jonas R.M., De Waele, Jorrit, Marcq, Elly, Van Loenhout, Jinthe, Lion, Eva, Van den Bergh, Johan M.J., Jesenofsky, Ralf, Masamune, Atsushi, Roeyen, Geert, Pauwels, Patrick, Lardon, Filip, Peeters, Marc, Smits, Evelien L.J.
Publicado 2017

Novel combination immunotherapy for pancreatic cancer: potent anti‐tumor effects with CD40 agonist and interleukin‐15 treatment

por Van Audenaerde, Jonas RM, Marcq, Elly, von Scheidt, Bianca, Davey, Ashleigh S, Oliver, Amanda J, De Waele, Jorrit, Quatannens, Delphine, Van Loenhout, Jinthe, Pauwels, Patrick, Roeyen, Geert, Lardon, Filip, Slaney, Clare Y, Peeters, Marc, Kershaw, Michael H, Darcy, Phillip K, Smits, Evelien LJM
Publicado 2020