Heparan Sulfate Proteoglycans as Emerging Players in Synaptic Specificity

por Condomitti, Giuseppe, de Wit, Joris
Publicado 2018

Leucine-rich repeat-containing synaptic adhesion molecules as organizers of synaptic specificity and diversity

por Schroeder, Anna, de Wit, Joris
Publicado 2018

SorCS1-mediated sorting in dendrites maintains neurexin axonal surface polarization required for synaptic function

por Ribeiro, Luís F., Verpoort, Ben, Nys, Julie, Vennekens, Kristel M., Wierda, Keimpe D., de Wit, Joris
Publicado 2019

KIF2A deficiency causes early-onset neurodegeneration

por Ruiz-Reig, Nuria, Chehade, Georges, Hakanen, Janne, Aittaleb, Mohamed, Wierda, Keimpe, De Wit, Joris, Nguyen, Laurent, Gailly, Philippe, Tissir, Fadel
Publicado 2022

Transsynaptic Binding of Orphan Receptor GPR179 to Dystroglycan-Pikachurin Complex Is Essential for the Synaptic Organization of Photoreceptors

por Orlandi, Cesare, Omori, Yoshihiro, Wang, Yuchen, Cao, Yan, Ueno, Akiko, Roux, Michel J., Condomitti, Giuseppe, de Wit, Joris, Kanagawa, Motoi, Furukawa, Takahisa, Martemyanov, Kirill A.
Publicado 2018

MDGAs are fast-diffusing molecules that delay excitatory synapse development by altering neuroligin behavior

por Toledo, Andrea, Letellier, Mathieu, Bimbi, Giorgia, Tessier, Béatrice, Daburon, Sophie, Favereaux, Alexandre, Chamma, Ingrid, Vennekens, Kristel, Vanderlinden, Jeroen, Sainlos, Matthieu, de Wit, Joris, Choquet, Daniel, Thoumine, Olivier
Publicado 2022

Contribution of GABAergic interneurons to amyloid-β plaque pathology in an APP knock-in mouse model

por Rice, Heather C., Marcassa, Gabriele, Chrysidou, Iordana, Horré, Katrien, Young-Pearse, Tracy L., Müller, Ulrike C., Saito, Takashi, Saido, Takaomi C., Vassar, Robert, de Wit, Joris, De Strooper, Bart
Publicado 2020

Lowering Synaptogyrin-3 expression rescues Tau-induced memory defects and synaptic loss in the presence of microglial activation

por Largo-Barrientos, Pablo, Apóstolo, Nuno, Creemers, Eline, Callaerts-Vegh, Zsuzsanna, Swerts, Jef, Davies, Caitlin, McInnes, Joseph, Wierda, Keimpe, De Strooper, Bart, Spires-Jones, Tara, de Wit, Joris, Uytterhoeven, Valerie, Verstreken, Patrik
Publicado 2021

Synapse type-specific proteomic dissection identifies IgSF8 as a hippocampal CA3 microcircuit organizer

por Apóstolo, Nuno, Smukowski, Samuel N., Vanderlinden, Jeroen, Condomitti, Giuseppe, Rybakin, Vasily, ten Bos, Jolijn, Trobiani, Laura, Portegies, Sybren, Vennekens, Kristel M., Gounko, Natalia V., Comoletti, Davide, Wierda, Keimpe D., Savas, Jeffrey N., de Wit, Joris
Publicado 2020

Hydrop enables droplet-based single-cell ATAC-seq and single-cell RNA-seq using dissolvable hydrogel beads

por De Rop, Florian V, Ismail, Joy N, Bravo González-Blas, Carmen, Hulselmans, Gert J, Flerin, Christopher Campbell, Janssens, Jasper, Theunis, Koen, Christiaens, Valerie M, Wouters, Jasper, Marcassa, Gabriele, de Wit, Joris, Poovathingal, Suresh, Aerts, Stein
Publicado 2022

Synaptogenic activity of the axon guidance molecule Robo2 underlies hippocampal circuit function

por Blockus, Heike, Rolotti, Sebi V., Szoboszlay, Miklos, Peze-Heidsieck, Eugénie, Ming, Tiffany, Schroeder, Anna, Apostolo, Nuno, Vennekens, Kristel M., Katsamba, Phinikoula S., Bahna, Fabiana, Mannepalli, Seetha, Ahlsen, Goran, Honig, Barry, Shapiro, Lawrence, de Wit, Joris, Losonczy, Attila, Polleux, Franck
Publicado 2021

Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins

por Elegheert, Jonathan, Cvetkovska, Vedrana, Clayton, Amber J., Heroven, Christina, Vennekens, Kristel M., Smukowski, Samuel N., Regan, Michael C., Jia, Wanyi, Smith, Alexandra C., Furukawa, Hiro, Savas, Jeffrey N., de Wit, Joris, Begbie, Jo, Craig, Ann Marie, Aricescu, A. Radu
Publicado 2017

Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins

por Elegheert, Jonathan, Cvetkovska, Vedrana, Clayton, Amber J., Heroven, Christina, Vennekens, Kristel M., Smukowski, Samuel N., Regan, Michael C., Jia, Wanyi, Smith, Alexandra C., Furukawa, Hiro, Savas, Jeffrey N., de Wit, Joris, Begbie, Jo, Craig, Ann Marie, Aricescu, A. Radu
Publicado 2017

Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins

por Elegheert, Jonathan, Cvetkovska, Vedrana, Clayton, Amber J., Heroven, Christina, Vennekens, Kristel M., Smukowski, Samuel N., Regan, Michael C., Jia, Wanyi, Smith, Alexandra C., Furukawa, Hiro, Savas, Jeffrey N., de Wit, Joris, Begbie, Jo, Craig, Ann Marie, Aricescu, A. Radu
Publicado 2021

Tau association with synaptic vesicles causes presynaptic dysfunction

por Zhou, Lujia, McInnes, Joseph, Wierda, Keimpe, Holt, Matthew, Herrmann, Abigail G., Jackson, Rosemary J., Wang, Yu-Chun, Swerts, Jef, Beyens, Jelle, Miskiewicz, Katarzyna, Vilain, Sven, Dewachter, Ilse, Moechars, Diederik, De Strooper, Bart, Spires-Jones, Tara L., De Wit, Joris, Verstreken, Patrik
Publicado 2017

Early alterations in the MCH system link aberrant neuronal activity and sleep disturbances in a mouse model of Alzheimer’s disease

por Calafate, Sara, Özturan, Gökhan, Thrupp, Nicola, Vanderlinden, Jeroen, Santa-Marinha, Luísa, Morais-Ribeiro, Rafaela, Ruggiero, Antonella, Bozic, Ivan, Rusterholz, Thomas, Lorente-Echeverría, Blanca, Dias, Marcelo, Chen, Wei-Ting, Fiers, Mark, Lu, Ashley, Vlaeminck, Ine, Creemers, Eline, Craessaerts, Katleen, Vandenbempt, Joris, van Boekholdt, Luuk, Poovathingal, Suresh, Davie, Kristofer, Thal, Dietmar Rudolf, Wierda, Keimpe, Oliveira, Tiago Gil, Slutsky, Inna, Adamantidis, Antoine, De Strooper, Bart, de Wit, Joris
Publicado 2023

A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation

por Voet, Sofie, Mc Guire, Conor, Hagemeyer, Nora, Martens, Arne, Schroeder, Anna, Wieghofer, Peter, Daems, Carmen, Staszewski, Ori, Vande Walle, Lieselotte, Jordao, Marta Joana Costa, Sze, Mozes, Vikkula, Hanna-Kaisa, Demeestere, Delphine, Van Imschoot, Griet, Scott, Charlotte L., Hoste, Esther, Gonçalves, Amanda, Guilliams, Martin, Lippens, Saskia, Libert, Claude, Vandenbroucke, Roos E., Kim, Ki-Wook, Jung, Steffen, Callaerts-Vegh, Zsuzsanna, Callaerts, Patrick, de Wit, Joris, Lamkanfi, Mohamed, Prinz, Marco, van Loo, Geert
Publicado 2018