Measuring the effect of drug treatments on primary human CD8+ T cell activation and cytolytic potential

por Loo Yau, Helen, De Carvalho, Daniel D.
Publicado 2021

Pharmacological DNA demethylation: Implications for cancer immunotherapy

por Roulois, David, Yau, Helen Loo, De Carvalho, Daniel D.
Publicado 2015

Drug-induced activation of “junk” DNA – A path to combat cancer therapy resistance?

por Classon, Marie, LaMarco, Kelly, De Carvalho, Daniel D.
Publicado 2017

Epigenetic Modifications as Therapeutic Targets

por Kelly, Theresa K, De Carvalho, Daniel D, Jones, Peter A
Publicado 2010

Nucleosomes Containing Methylated DNA Stabilize DNA Methyltransferases 3A/3B and Ensure Faithful Epigenetic Inheritance

por Sharma, Shikhar, De Carvalho, Daniel D., Jeong, Shinwu, Jones, Peter A., Liang, Gangning
Publicado 2011

TGF-β-associated extracellular matrix genes link cancer-associated fibroblasts to immune evasion and immunotherapy failure

por Chakravarthy, Ankur, Khan, Lubaba, Bensler, Nathan Peter, Bose, Pinaki, De Carvalho, Daniel D.
Publicado 2018

Regulation of TRAIL expression by PRAME and EZH2 as potential therapeutic target against solid tumors

por Mello, Barbara P, de Carvalho, Daniel D, Campos, Antonio HJFM, Soares, Fernando A, Amarante-Mendes, Gustavo P
Publicado 2013

SNF5 Is an Essential Executor of Epigenetic Regulation during Differentiation

por You, Jueng Soo, De Carvalho, Daniel D., Dai, Chao, Liu, Minmin, Pandiyan, Kurinji, Zhou, Xianghong J., Liang, Gangning, Jones, Peter A.
Publicado 2013

Sensitive and reproducible cell-free methylome quantification with synthetic spike-in controls

por Wilson, Samantha L., Shen, Shu Yi, Harmon, Lauren, Burgener, Justin M., Triche, Tim, Bratman, Scott V., De Carvalho, Daniel D., Hoffman, Michael M.
Publicado 2022

Constitutive Androstane Receptor Ligands Modulate the Anti-Tumor Efficacy of Paclitaxel in Non-Small Cell Lung Cancer Cells

por Fukumasu, Heidge, Rochetti, Arina L., Pires, Pedro R. L., Silva, Edson R., Mesquita, Ligia G., Strefezzi, Ricardo F., De Carvalho, Daniel D., Dagli, Maria L.
Publicado 2014

Aberrant DNA methylation reprogramming during induced pluripotent stem cell generation is dependent on the choice of reprogramming factors

por Planello, Aline C, Ji, Junfeng, Sharma, Vivek, Singhania, Rajat, Mbabaali, Faridah, Müller, Fabian, Alfaro, Javier A, Bock, Christoph, De Carvalho, Daniel D, Batada, Nizar N
Publicado 2014

Pre-neoplastic epigenetic disruption of transcriptional enhancers in chronic inflammation

por Planello, Aline C., Singhania, Rajat, Kron, Ken J., Bailey, Swneke D., Roulois, David, Lupien, Mathieu, Line, Sérgio R. Peres, de Souza, Ana Paula, De Carvalho, Daniel D.
Publicado 2016

Epigenetic regulation of nitric oxide synthase 2, inducible (Nos2) by NLRC4 inflammasomes involves PARP1 cleavage

por Buzzo, Carina de Lima, Medina, Tiago, Branco, Laura M., Lage, Silvia L., Ferreira, Luís Carlos de Souza, Amarante-Mendes, Gustavo P., Hottiger, Michael O., De Carvalho, Daniel D., Bortoluci, Karina R.
Publicado 2017

METABOLOGENOMIC CHARACTERIZATION UNCOVERS HETEROGENEITY AMONG IDH MUTANT GLIOMAS

por Ajisebutu, Andrew, Nassiri, Farshad, Wang, Justin Z, Mamatjan, Yasin, Nejad, Romina, Patil, Vikas, Liu, Jeff, Voisin, Mathew R, Mansouri, Sheila, Karimi, Shirin, Chakravarthy, Ankur, Chen, Eric, De Carvalho, Daniel D, Aldape, Kenneth, Zadeh, Gelareh
Publicado 2023

PLAG1 dampens protein synthesis to promote human hematopoietic stem cell self-renewal

por Keyvani Chahi, Ava, Belew, Muluken S., Xu, Joshua, Chen, He Tian Tony, Rentas, Stefan, Voisin, Veronique, Krivdova, Gabriela, Lechman, Eric, Marhon, Sajid A., De Carvalho, Daniel D., Dick, John E., Bader, Gary D., Hope, Kristin J.
Publicado 2022

The chromatin and single-cell transcriptional landscapes of CD4 T cells in inflammatory bowel disease link risk loci with a proinflammatory Th17 cell population

por Medina, Tiago S., Murison, Alex, Smith, Michelle, Kinker, Gabriela S., Chakravarthy, Ankur, Vitiello, Glauco A. F., Turpin, Williams, Shen, Shu Yi, Yau, Helen L., Sarmento, Olga F., Faubion, William, Lupien, Mathieu, Silverberg, Mark S., Arrowsmith, Cheryl H., De Carvalho, Daniel D.
Publicado 2023

BCR–ABL1-induced downregulation of WASP in chronic myeloid leukemia involves epigenetic modification and contributes to malignancy

por Pereira, Welbert O, De Carvalho, Daniel D, Zenteno, Maria Emilia, Ribeiro, Beatriz F, Jacysyn, Jacqueline F, Sardinha, Luiz R, Zanichelli, Maria A, Hamerschlak, Nelson, Jones, Gareth E, Pagnano, Katia B, Castro, Fabiola A, Calle, Yolanda, Amarante-Mendes, Gustavo P
Publicado 2017

Proceedings of the inaugural Dark Genome Symposium: November 2022

por Boeke, Jef D., Burns, Kathleen H., Chiappinelli, Katherine B., Classon, Marie, Coffin, John M., DeCarvalho, Daniel D., Dukes, Joseph D., Greenbaum, Benjamin, Kassiotis, George, Knutson, Sarah K., Levine, Arnold J., Nath, Avindra, Papa, Sophie, Rios, Daniel, Sedivy, John, Ting, David T.
Publicado 2023

H3K9 methylation drives resistance to androgen receptor–antagonist therapy in prostate cancer

por Baratchian, Mehdi, Tiwari, Ritika, Khalighi, Sirvan, Chakravarthy, Ankur, Yuan, Wei, Berk, Michael, Li, Jianneng, Guerinot, Amy, de Bono, Johann, Makarov, Vladimir, Chan, Timothy A., Silverman, Robert H., Stark, George R., Varadan, Vinay, De Carvalho, Daniel D., Chakraborty, Abhishek A., Sharifi, Nima
Publicado 2022

Tumor-Naïve Multimodal Profiling of Circulating Tumor DNA in Head and Neck Squamous Cell Carcinoma

por Burgener, Justin M., Zou, Jinfeng, Zhao, Zhen, Zheng, Yangqiao, Shen, Shu Yi, Huang, Shao Hui, Keshavarzi, Sareh, Xu, Wei, Liu, Fei-Fei, Liu, Geoffrey, Waldron, John N., Weinreb, Ilan, Spreafico, Anna, Siu, Lillian L., de Almeida, John R., Goldstein, David P., Hoffman, Michael M., De Carvalho, Daniel D., Bratman, Scott V.
Publicado 2021