A Real-Time All-Atom Structural Search Engine for Proteins

por Gonzalez, Gabriel, Hannigan, Brett, DeGrado, William F.
Publicado 2014

An Assay Suitable for High Throughput Screening of Anti-Influenza Drugs

por Mao, Lili, Wang, Jun, DeGrado, William F., Inouye, Masayori
Publicado 2013

Influenza A M2 Inhibitor Binding Understood through Mechanisms of Excess Proton Stabilization and Channel Dynamics

por Watkins, Laura C., DeGrado, William F., Voth, Gregory A.
Publicado 2020

Brilacidin, a COVID‐19 drug candidate, demonstrates broad‐spectrum antiviral activity against human coronaviruses OC43, 229E, and NL63 through targeting both the virus and the host...

por Hu, Yanmei, Jo, Hyunil, DeGrado, William F., Wang, Jun
Publicado 2022

Engineered single- and multi-cell chemotaxis pathways in E. coli

por Goldberg, Shalom D, Derr, Paige, DeGrado, William F, Goulian, Mark
Publicado 2009

Exploring Histidine Conformations in the M2 Channel Lumen of the Influenza A Virus at Neutral pH via Molecular Simulations

por Dong, Hao, Fiorin, Giacomo, DeGrado, William F., Klein, Michael L.
Publicado 2013

Proton Release from the Histidine-Tetrad in the M2 Channel of the Influenza A Virus

por Dong, Hao, Fiorin, Giacomo, DeGrado, William F., Klein, Michael L.
Publicado 2014

Structural organization and interactions of transmembrane domains in tetraspanin proteins

por Kovalenko, Oleg V, Metcalf, Douglas G, DeGrado, William F, Hemler, Martin E
Publicado 2005

Assembly of the Transmembrane Domain of E. coli PhoQ Histidine Kinase: Implications for Signal Transduction from Molecular Simulations

por Lemmin, Thomas, Soto, Cinque S., Clinthorne, Graham, DeGrado, William F., Dal Peraro, Matteo
Publicado 2013

SNAC-tag for Sequence-specific Chemical Protein Cleavage

por Dang, Bobo, Mravic, Marco, Hu, Hailin, Schmidt, Nathan, Mensa, Bruk, DeGrado, William F.
Publicado 2019

Deep Mutational Scanning Reveals the Structural Basis for α-Synuclein Activity

por Newberry, Robert W., Leong, Jaime T., Chow, Eric D., Kampmann, Martin, DeGrado, William F.
Publicado 2020

Crystal structure of an amphiphilic foldamer reveals a 48-mer assembly comprising a hollow truncated octahedron

por Pavone, Vincenzo, Zhang, Shao-Qing, Merlino, Antonello, Lombardi, Angela, Wu, Yibing, DeGrado, William F.
Publicado 2014

The CD3ζ adaptor structure determines functional differences between human and mouse CD16 Fc receptor signaling

por Aguilar, Oscar A., Fong, Lam-Kiu, Ishiyama, Kenichi, DeGrado, William F., Lanier, Lewis L.
Publicado 2022

Hexamethylene amiloride binds the SARS‐CoV‐2 envelope protein at the protein–lipid interface

por Somberg, Noah H., Medeiros‐Silva, João, Jo, Hyunil, Wang, Jun, DeGrado, William F., Hong, Mei
Publicado 2023

Functional Analysis of the Transmembrane Domain in Paramyxovirus F Protein-Mediated Membrane Fusion

por Bissonnette, Mei Lin Z., Donald, Jason E., DeGrado, William F., Jardetzky, Theodore S., Lamb, Robert A.
Publicado 2009

Structure of the Amantadine Binding Site of Influenza M2 Proton Channels In Lipid Bilayers

por Cady, Sarah D., Schmidt-Rohr, Klaus, Wang, Jun, Soto, Cinque S., DeGrado, William F., Hong, Mei
Publicado 2010

Graphene Symmetry Amplified by Designed Peptide Self-Assembly

por Mustata, Gina-Mirela, Kim, Yong Ho, Zhang, Jian, DeGrado, William F., Grigoryan, Gevorg, Wanunu, Meni
Publicado 2016

Allosteric mechanism of signal transduction in the two-component system histidine kinase PhoQ

por Mensa, Bruk, Polizzi, Nicholas F, Molnar, Kathleen S, Natale, Andrew M, Lemmin, Thomas, DeGrado, William F
Publicado 2021

4-Cyanoindole-2′-deoxyribonucleoside as a Dual Fluorescence and Infrared Probe of DNA Structure and Dynamics

por Ahmed, Ismail A., Acharyya, Arusha, Eng, Christina M., Rodgers, Jeffrey M., DeGrado, William F., Jo, Hyunil, Gai, Feng
Publicado 2019

Short peptides self-assemble to produce catalytic amyloids

por Rufo, Caroline M., Moroz, Yurii S., Moroz, Olesia V., Stöhr, Jan, Smith, Tyler A., Hu, Xiaozhen, DeGrado, William F., Korendovych, Ivan V.
Publicado 2014