Tumorigenicity of RTK/RAS in urothelium

por Wu, Xue-Ru, Mendelsohn, Cathy, DeGraff, David J.
Publicado 2015

Wnt/β-Catenin activation promotes prostate tumor progression in a mouse model

por Yu, Xiuping, Wang, Yongqing, DeGraff, David J., Wills, Marcia L., Matusik, Robert J.
Publicado 2010

Activation of NF-kappa B Signaling Promotes Growth of Prostate Cancer Cells in Bone

por Jin, Renjie, Sterling, Julie A., Edwards, James R., DeGraff, David J., Lee, Changki, Park, Serk In, Matusik, Robert J.
Publicado 2013

Intratumoral Heterogeneity Promotes Collective Cancer Invasion through NOTCH1 Variation

por Torab, Peter, Yan, Yue, Ahmed, Mona, Yamashita, Hironobu, Warrick, Joshua I., Raman, Jay D., DeGraff, David J., Wong, Pak Kin
Publicado 2021

Maintenance of the bladder cancer precursor urothelial hyperplasia requires FOXA1 and persistent expression of oncogenic HRAS

por Yee, Christopher H., Zheng, Zongyu, Shuman, Lauren, Yamashita, Hironobu, Warrick, Joshua I., Wu, Xue-Ru, Raman, Jay D., DeGraff, David J.
Publicado 2019

Evaluation of PD-L1 and other immune markers in bladder urothelial carcinoma stratified by histologic variants and molecular subtypes

por Li, Huili, Zhang, Qingzhao, Shuman, Lauren, Kaag, Matthew, Raman, Jay D., Merrill, Suzanne, DeGraff, David J., Warrick, Joshua I., Chen, Guoli
Publicado 2020

Dominant role of CDKN2B/p15INK4B of 9p21.3 tumor suppressor hub in inhibition of cell-cycle and glycolysis

por Xia, Yong, Liu, Yan, Yang, Chao, Simeone, Diane M., Sun, Tung-Tien, DeGraff, David J., Tang, Moon-shong, Zhang, Yingkai, Wu, Xue-Ru
Publicado 2021

TBX2 Drives Neuroendocrine Prostate Cancer through Exosome-Mediated Repression of miR-200c-3p

por Patel, Girijesh Kumar, Dutta, Sayanika, Mahmud Syed, Mosharaf, Ramachandran, Sabarish, Sharma, Monica, Rajamanickam, Venkatesh, Ganapathy, Vadivel, DeGraff, David J., Pruitt, Kevin, Tripathi, Manisha, Nandana, Srinivas
Publicado 2021

Characterization of Histone Deacetylase Expression Within In Vitro and In Vivo Bladder Cancer Model Systems

por Buckwalter, Jenna M., Chan, Wilson, Shuman, Lauren, Wildermuth, Thomas, Ellis-Mohl, Justine, Walter, Vonn, Warrick, Joshua I., Wu, Xue-Ru, Kaag, Matt, Raman, Jay D., DeGraff, David J.
Publicado 2019

SOX2 expression in the developing, adult, as well as diseased prostate

por Yu, Xiuping, Cates, Justin M., Morrissey, Colm, You, Chaochen, Grabowska, Magdalena M., Zhang, Jianghong, DeGraff, David J., Strand, Douglas W., Franco, Omar E., Lin-Tsai, Opal, Hayward, Simon W., Matusik, Robert J.
Publicado 2014

Repression of transcription factor AP-2 alpha by PPARγ reveals a novel transcriptional circuit in basal-squamous bladder cancer

por Yamashita, Hironobu, Kawasawa, Yuka I., Shuman, Lauren, Zheng, Zongyu, Tran, Truc, Walter, Vonn, Warrick, Joshua I., Chen, Guoli, Al-Ahmadie, Hikmat, Kaag, Matthew, Wong, Pak Kin, Raman, Jay D., DeGraff, David J.
Publicado 2019

A transcriptional network of cell cycle dysregulation in noninvasive papillary urothelial carcinoma

por Warrick, Joshua I., Knowles, Margaret A., Hurst, Carolyn D., Shuman, Lauren, Raman, Jay D., Walter, Vonn, Putt, Jeffrey, Dyrskjøt, Lars, Groeneveld, Clarice, Castro, Mauro A. A., Robertson, A. Gordon, DeGraff, David J.
Publicado 2022

FOXA1, GATA3 and PPARɣ Cooperate to Drive Luminal Subtype in Bladder Cancer: A Molecular Analysis of Established Human Cell Lines

por Warrick, Joshua I., Walter, Vonn, Yamashita, Hironobu, Chung, Eunah, Shuman, Lauren, Amponsa, Vasty Osei, Zheng, Zongyu, Chan, Wilson, Whitcomb, Tiffany L., Yue, Feng, Iyyanki, Tejaswi, Kawasawa, Yuka I., Kaag, Matthew, Guo, Wansong, Raman, Jay D., Park, Joo-Seop, DeGraff, David J.
Publicado 2016

Loss of the Urothelial Differentiation Marker FOXA1 Is Associated with High Grade, Late Stage Bladder Cancer and Increased Tumor Proliferation

por DeGraff, David J., Clark, Peter E., Cates, Justin M., Yamashita, Hironobu, Robinson, Victoria L., Yu, Xiuping, Smolkin, Mark E., Chang, Sam S., Cookson, Michael S., Herrick, Mary K., Shariat, Shahrokh F., Steinberg, Gary D., Frierson, Henry F., Wu, Xue-Ru, Theodorescu, Dan, Matusik, Robert J.
Publicado 2012

Subtype-associated epigenomic landscape and 3D genome structure in bladder cancer

por Iyyanki, Tejaswi, Zhang, Baozhen, Wang, Qixuan, Hou, Ye, Jin, Qiushi, Xu, Jie, Yang, Hongbo, Liu, Tingting, Wang, Xiaotao, Song, Fan, Luan, Yu, Yamashita, Hironobu, Chien, Ruby, Lyu, Huijue, Zhang, Lijun, Wang, Lu, Warrick, Joshua, Raman, Jay D., Meeks, Joshua J., DeGraff, David J., Yue, Feng
Publicado 2021

Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming

por Buj, Raquel, Chen, Chi-Wei, Dahl, Erika S., Leon, Kelly E., Kuskovsky, Rostislav, Maglakelidze, Natella, Navaratnarajah, Maithili, Zhang, Gao, Doan, Mary T., Jiang, Helen, Zaleski, Michael, Kutzler, Lydia, Lacko, Holly, Lu, Yiling, Mills, Gordon B., Gowda, Raghavendra, Robertson, Gavin P., Warrick, Joshua I., Herlyn, Meenhard, Imamura, Yuka, Kimball, Scot R., DeGraff, David J., Snyder, Nathaniel W., Aird, Katherine M.
Publicado 2019

An integrated multi-omics analysis identifies prognostic molecular subtypes of non-muscle-invasive bladder cancer

por Lindskrog, Sia Viborg, Prip, Frederik, Lamy, Philippe, Taber, Ann, Groeneveld, Clarice S., Birkenkamp-Demtröder, Karin, Jensen, Jørgen Bjerggaard, Strandgaard, Trine, Nordentoft, Iver, Christensen, Emil, Sokac, Mateo, Birkbak, Nicolai J., Maretty, Lasse, Hermann, Gregers G., Petersen, Astrid C., Weyerer, Veronika, Grimm, Marc-Oliver, Horstmann, Marcus, Sjödahl, Gottfrid, Höglund, Mattias, Steiniche, Torben, Mogensen, Karin, de Reyniès, Aurélien, Nawroth, Roman, Jordan, Brian, Lin, Xiaoqi, Dragicevic, Dejan, Ward, Douglas G., Goel, Anshita, Hurst, Carolyn D., Raman, Jay D., Warrick, Joshua I., Segersten, Ulrika, Sikic, Danijel, van Kessel, Kim E. M., Maurer, Tobias, Meeks, Joshua J., DeGraff, David J., Bryan, Richard T., Knowles, Margaret A., Simic, Tatjana, Hartmann, Arndt, Zwarthoff, Ellen C., Malmström, Per-Uno, Malats, Núria, Real, Francisco X., Dyrskjøt, Lars
Publicado 2021

FOXA1 repression drives lineage plasticity and immune heterogeneity in bladder cancers with squamous differentiation

por Warrick, Joshua I., Hu, Wenhuo, Yamashita, Hironobu, Walter, Vonn, Shuman, Lauren, Craig, Jenna M., Gellert, Lan L., Castro, Mauro A. A., Robertson, A. Gordon, Kuo, Fengshen, Ostrovnaya, Irina, Sarungbam, Judy, Chen, Ying-bei, Gopalan, Anuradha, Sirintrapun, Sahussapont J., Fine, Samson W., Tickoo, Satish K., Kim, Kwanghee, Thomas, Jasmine, Karan, Nagar, Gao, Sizhi Paul, Clinton, Timothy N., Lenis, Andrew T., Chan, Timothy A., Chen, Ziyu, Rao, Manisha, Hollman, Travis J., Li, Yanyun, Socci, Nicholas D., Chavan, Shweta, Viale, Agnes, Mohibullah, Neeman, Bochner, Bernard H., Pietzak, Eugene J., Teo, Min Yuen, Iyer, Gopa, Rosenberg, Jonathan E., Bajorin, Dean F., Kaag, Matthew, Merrill, Suzanne B., Joshi, Monika, Adam, Rosalyn, Taylor, John A., Clark, Peter E., Raman, Jay D., Reuter, Victor E., Chen, Yu, Funt, Samuel A., Solit, David B., DeGraff, David J., Al-Ahmadie, Hikmat A.
Publicado 2022

Author Correction: FOXA1 repression drives lineage plasticity and immune heterogeneity in bladder cancers with squamous differentiation

por Warrick, Joshua I., Hu, Wenhuo, Yamashita, Hironobu, Walter, Vonn, Shuman, Lauren, Craig, Jenna M., Gellert, Lan L., Castro, Mauro A. A., Robertson, A. Gordon, Kuo, Fengshen, Ostrovnaya, Irina, Sarungbam, Judy, Chen, Ying-bei, Gopalan, Anuradha, Sirintrapun, Sahussapont J., Fine, Samson W., Tickoo, Satish K., Kim, Kwanghee, Thomas, Jasmine, Karan, Nagar, Gao, Sizhi Paul, Clinton, Timothy N., Lenis, Andrew T., Chan, Timothy A., Chen, Ziyu, Rao, Manisha, Hollman, Travis J., Li, Yanyun, Socci, Nicholas D., Chavan, Shweta, Viale, Agnes, Mohibullah, Neeman, Bochner, Bernard H., Pietzak, Eugene J., Teo, Min Yuen, Iyer, Gopa, Rosenberg, Jonathan E., Bajorin, Dean F., Kaag, Matthew, Merrill, Suzanne B., Joshi, Monika, Adam, Rosalyn, Taylor, John A., Clark, Peter E., Raman, Jay D., Reuter, Victor E., Chen, Yu, Funt, Samuel A., Solit, David B., DeGraff, David J., Al-Ahmadie, Hikmat A.
Publicado 2022