Drug discovery of small molecules targeting the higher-order hTERT promoter G-quadruplex

por Monsen, Robert C., Maguire, Jon M., DeLeeuw, Lynn W., Chaires, Jonathan B., Trent, John O.
Publicado 2022

Human POT1 unfolds G-quadruplexes by conformational selection

por Chaires, Jonathan B, Gray, Robert D, Dean, William L, Monsen, Robert, DeLeeuw, Lynn W, Stribinskis, Vilius, Trent, John O
Publicado 2020

POT1 stability and binding measured by fluorescence thermal shift assays

por DeLeeuw, Lynn W., Monsen, Robert C., Petrauskas, Vytautas, Gray, Robert D., Baranauskiene, Lina, Matulis, Daumantas, Trent, John O., Chaires, Jonathan B.
Publicado 2021

Long promoter sequences form higher-order G-quadruplexes: an integrative structural biology study of c-Myc, k-Ras and c-Kit promoter sequences

por Monsen, Robert C, DeLeeuw, Lynn W, Dean, William L, Gray, Robert D, Chakravarthy, Srinivas, Hopkins, Jesse B, Chaires, Jonathan B, Trent, John O
Publicado 2022