Impact of lower challenge doses of enterotoxigenic Escherichia coli on clinical outcome, intestinal colonization and immune responses in adult volunteers

por Chakraborty, Subhra, Harro, Clayton, DeNearing, Barbara, Brubaker, Jessica, Connor, Sean, Maier, Nicole, Dally, Len, Flores, Jorge, Bourgeois, A. Louis, Walker, Richard, Sack, David A.
Publicado 2018

Live attenuated enterotoxigenic Escherichia coli (ETEC) vaccine with dmLT adjuvant protects human volunteers against virulent experimental ETEC challenge

por Harro, Clayton, Louis Bourgeois, A., Sack, David, Walker, Richard, DeNearing, Barbara, Brubaker, Jessica, Maier, Nicole, Fix, Alan, Dally, Len, Chakraborty, Subhra, Clements, John D., Saunders, Ingelise, Darsley, Michael J.
Publicado 2019

Clinical endpoints in the controlled human challenge model for Shigella: A call for standardization and the development of a disease severity score

por Porter, Chad K., Lynen, Amanda, Riddle, Mark S., Talaat, Kawsar, Sack, David, Gutiérrez, Ramiro L., McKenzie, Robin, DeNearing, Barbara, Feijoo, Brittany, Kaminski, Robert W., Taylor, David N., Kirkpatrick, Beth D., Bourgeois, A. Louis
Publicado 2018

An Evidenced-Based Scale of Disease Severity following Human Challenge with Enteroxigenic Escherichia coli

por Porter, Chad K., Riddle, Mark S., Alcala, Ashley N., Sack, David A., Harro, Clayton, Chakraborty, Subhra, Gutierrez, Ramiro L., Savarino, Stephen J., Darsley, Michael, McKenzie, Robin, DeNearing, Barbara, Steinsland, Hans, Tribble, David R., Bourgeois, A. Louis
Publicado 2016

Interrogation of a live-attenuated enterotoxigenic Escherichia coli vaccine highlights features unique to wild-type infection

por Chakraborty, Subhra, Randall, Arlo, Vickers, Tim J., Molina, Doug, Harro, Clayton D., DeNearing, Barbara, Brubaker, Jessica, Sack, David A., Bourgeois, A. Louis, Felgner, Philip L., Liang, Xiaowu, Mani, Sachin, Wenzel, Heather, Townsend, R. Reid, Gilmore, Petra E., Darsley, Michael J., Rasko, David A., Fleckenstein, James M.
Publicado 2019

Immune response characterization in a human challenge study with a Shigella flexneri 2a bioconjugate vaccine

por Clarkson, Kristen A., Talaat, Kawsar R., Alaimo, Cristina, Martin, Patricia, Bourgeois, A. Louis, Dreyer, Anita, Porter, Chad K., Chakraborty, Subhra, Brubaker, Jessica, Elwood, Daniel, Frölich, Rahel, DeNearing, Barbara, Weerts, Hailey P., Feijoo, Brittany, Halpern, Jane, Sack, David, Riddle, Mark S., Fonck, Veronica Gambillara, Kaminski, Robert W.
Publicado 2021

Human challenge study with a Shigella bioconjugate vaccine: Analyses of clinical efficacy and correlate of protection

por Talaat, Kawsar R., Alaimo, Cristina, Martin, Patricia, Bourgeois, A. Louis, Dreyer, Anita M., Kaminski, Robert W., Porter, Chad K., Chakraborty, Subhra, Clarkson, Kristen A., Brubaker, Jessica, Elwood, Daniel, Frölich, Rahel, DeNearing, Barbara, Weerts, Hailey, Feijoo, Brittany L., Halpern, Jane, Sack, David, Riddle, Mark S., Fonck, Veronica Gambillara
Publicado 2021

Campylobacter jejuni transcriptional and genetic adaptation during human infection

por Crofts, Alexander A., Poly, Frédéric M., Ewing, Cheryl P., Kuroiwa, Janelle M., Rimmer, Joanna E., Harro, Clayton, Sack, David, Talaat, Kawsar R., Porter, Chad K., Gutierrez, Ramiro L., DeNearing, Barbara, Brubaker, Jessica, Laird, Renée M., Maue, Alexander C., Jaep, Kayla, Alcala, Ashley, Tribble, David R., Riddle, Mark. S., Ramakrishnan, Amritha, McCoy, Andrea J., Davies, Bryan W., Guerry, Patricia, Trent, M. Stephen
Publicado 2018