Duplex structural differences and not 2′-hydroxyls explain the more stable binding of HIV-reverse transcriptase to RNA-DNA versus DNA-DNA

por Olimpo, Jeffrey T., DeStefano, Jeffrey J.
Publicado 2010

Alternative divalent cations (Zn(2+), Co(2+), and Mn(2+)) are not mutagenic at conditions optimal for HIV-1 reverse transcriptase activity

por Achuthan, Vasudevan, DeStefano, Jeffrey J
Publicado 2015

Selection of primer-template sequences that bind human immunodeficiency virus reverse transcriptase with high affinity

por DeStefano, Jeffrey J., Cristofaro, Jason V.
Publicado 2006

HIV Reverse Transcriptase Pre-Steady-State Kinetic Analysis of Chain Terminators and Translocation Inhibitors Reveals Interactions between Magnesium and Nucleotide 3′-OH

por Dilmore, Christopher R., DeStefano, Jeffrey J.
Publicado 2021

Xeno-Nucleic Acid (XNA) 2’-Fluoro-Arabino Nucleic Acid (FANA) Aptamers to the Receptor-Binding Domain of SARS-CoV-2 S Protein Block ACE2 Binding

por Alves Ferreira-Bravo, Irani, DeStefano, Jeffrey J.
Publicado 2021

Selection of Primer–Template Sequences That Bind with Enhanced Affinity to Vaccinia Virus E9 DNA Polymerase

por DeStefano, Jeffrey J., Iseni, Frédéric, Tarbouriech, Nicolas
Publicado 2022

Correction: Detection of Cyclic Diguanylate G-Octaplex Assembly and Interaction with Proteins

por Lieberman, Ori J., DeStefano, Jeffrey J., Lee, Vincent T.
Publicado 2013

Structure of HIV-1 RT/dsRNA initiation complex prior to nucleotide incorporation

por Das, Kalyan, Martinez, Sergio E., DeStefano, Jeffrey J., Arnold, Eddy
Publicado 2019

Selection of 2′-deoxy-2′-fluoroarabinonucleotide (FANA) aptamers that bind HIV-1 reverse transcriptase with picomolar affinity

por Alves Ferreira-Bravo, Irani, Cozens, Christopher, Holliger, Philipp, DeStefano, Jeffrey J.
Publicado 2015

Viral Reverse Transcriptases Show Selective High Affinity Binding to DNA-DNA Primer-Templates that Resemble the Polypurine Tract

por Nair, Gauri R., Dash, Chandravanu, Le Grice, Stuart F. J., DeStefano, Jeffrey J.
Publicado 2012

Selection of 2′-Deoxy-2′-Fluoroarabino Nucleic Acid (FANA) Aptamers That Bind HIV-1 Integrase with Picomolar Affinity

por Rose, Kevin M., Alves Ferreira-Bravo, Irani, Li, Min, Craigie, Robert, Ditzler, Mark A., Holliger, Philipp, DeStefano, Jeffrey J.
Publicado 2019

Inhibition of SARS-CoV-2 Infection in Human Airway Epithelium with a Xeno-Nucleic Acid Aptamer

por Razi, Niayesh, Li, Weizhong, Ignacio, Maxinne A., Loube, Jeffrey M., Agostino, Eva L., Zhu, Xiaoping, Scull, Margaret A., DeStefano, Jeffrey J.
Publicado 2023

Inhibition of SARS-CoV-2 infection in human airway epithelium with a xeno-nucleic acid aptamer

por Razi, Niayesh, Li, Weizhong, Ignacio, Maxinne A., Loube, Jeffrey M., Agostino, Eva L., Zhu, Xiaoping, Scull, Margaret A., DeStefano, Jeffrey J.
Publicado 2023

Crystal Structure of a Retroviral Polyprotein: Prototype Foamy Virus Protease-Reverse Transcriptase (PR-RT)

por Harrison, Jerry Joe E. K., Tuske, Steve, Das, Kalyan, Ruiz, Francesc X., Bauman, Joseph D., Boyer, Paul L., DeStefano, Jeffrey J., Hughes, Stephen H., Arnold, Eddy
Publicado 2021

Cryo-EM structure of the HIV-1 Pol polyprotein provides insights into virion maturation

por Harrison, Jerry Joe E. K., Passos, Dario Oliveira, Bruhn, Jessica F., Bauman, Joseph D., Tuberty, Lynda, DeStefano, Jeffrey J., Ruiz, Francesc Xavier, Lyumkis, Dmitry, Arnold, Eddy
Publicado 2022

Integrative structural biology studies of HIV-1 reverse transcriptase binding to a high-affinity DNA aptamer

por Tuske, Steve, Zheng, Jie, Olson, Erik D., Ruiz, Francesc X., Pascal, Bruce D., Hoang, Anthony, Bauman, Joseph D., Das, Kalyan, DeStefano, Jeffrey J., Musier-Forsyth, Karin, Griffin, Patrick R., Arnold, Eddy
Publicado 2020

Using a Concept Inventory to Reveal Student Thinking Associated with Common Misconceptions about Antibiotic Resistance

por Stevens, Ann M., Smith, Ann C., Marbach-Ad, Gili, Balcom, Sarah A., Buchner, John, Daniel, Sandra L., DeStefano, Jeffrey J., El-Sayed, Najib M., Frauwirth, Kenneth, Lee, Vincent T., McIver, Kevin S., Melville, Stephen B., Mosser, David M., Popham, David L., Scharf, Birgit E., Schubot, Florian D., Seyler, Richard W., Shields, Patricia Ann, Song, Wenxia, Stein, Daniel C., Stewart, Richard C., Thompson, Katerina V., Yang, Zhaomin, Yarwood, Stephanie A.
Publicado 2017