CRISPR-Cas9 interrogation of a putative fetal globin repressor in human erythroid cells

por Chung, Jennifer E., Magis, Wendy, Vu, Jonathan, Heo, Seok-Jin, Wartiovaara, Kirmo, Walters, Mark C., Kurita, Ryo, Nakamura, Yukio, Boffelli, Dario, Martin, David I. K., Corn, Jacob E., DeWitt, Mark A.
Publicado 2019

High-level correction of the sickle mutation is amplified in vivo during erythroid differentiation

por Magis, Wendy, DeWitt, Mark A., Wyman, Stacia K., Vu, Jonathan T., Heo, Seok-Jin, Shao, Shirley J., Hennig, Finn, Romero, Zulema G., Campo-Fernandez, Beatriz, Said, Suzanne, McNeill, Matthew S., Rettig, Garrett R., Sun, Yongming, Wang, Yu, Behlke, Mark A., Kohn, Donald B., Boffelli, Dario, Walters, Mark C., Corn, Jacob E., Martin, David I.K.
Publicado 2022

Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin

por Ravi, Nithin Sam, Wienert, Beeke, Wyman, Stacia K, Bell, Henry William, George, Anila, Mahalingam, Gokulnath, Vu, Jonathan T, Prasad, Kirti, Bandlamudi, Bhanu Prasad, Devaraju, Nivedhitha, Rajendiran, Vignesh, Syedbasha, Nazar, Pai, Aswin Anand, Nakamura, Yukio, Kurita, Ryo, Narayanasamy, Muthuraman, Balasubramanian, Poonkuzhali, Thangavel, Saravanabhavan, Marepally, Srujan, Velayudhan, Shaji R, Srivastava, Alok, DeWitt, Mark A, Crossley, Merlin, Corn, Jacob E, Mohankumar, Kumarasamypet M
Publicado 2022