Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia

por Sansom, Stephen N., Shikama-Dorn, Noriko, Zhanybekova, Saule, Nusspaumer, Gretel, Macaulay, Iain C., Deadman, Mary E., Heger, Andreas, Ponting, Chris P., Holländer, Georg A.
Publicado 2014

Developmental dynamics of the neural crest–mesenchymal axis in creating the thymic microenvironment

por Handel, Adam E., Cheuk, Stanley, Dhalla, Fatima, Maio, Stefano, Hübscher, Tania, Rota, Ioanna, Deadman, Mary E., Ekwall, Olov, Lütolf, Matthias, Weinberg, Kenneth, Holländer, Georg
Publicado 2022

Construction of Opa-Positive and Opa-Negative Strains of Neisseria meningitidis to Evaluate a Novel Meningococcal Vaccine

por Sadarangani, Manish, Hoe, J. Claire, Callaghan, Martin J., Jones, Claire, Chan, Hannah, Makepeace, Katherine, Daniels-Treffandier, Hélène, Deadman, Mary E., Bayliss, Christopher, Feavers, Ian, van der Ley, Peter, Pollard, Andrew J.
Publicado 2012

Correction: Construction of Opa-Positive and Opa-Negative Strains of Neisseria meningitidis to Evaluate a Novel Meningococcal Vaccine

por Sadarangani, Manish, Hoe, J. Claire, Callaghan, Martin J., Jones, Claire, Chan, Hannah, Makepeace, Katherine, Daniels-Treffandier, Hélène, Deadman, Mary E., Bayliss, Christopher, Feavers, Ian, van der Ley, Peter, Pollard, Andrew J.
Publicado 2013

Dynamic spatio‐temporal contribution of single β5t+ cortical epithelial precursors to the thymus medulla

por Mayer, Carlos E., Žuklys, Saulius, Zhanybekova, Saule, Ohigashi, Izumi, Teh, Hong‐Ying, Sansom, Stephen N., Shikama‐Dorn, Noriko, Hafen, Katrin, Macaulay, Iain C., Deadman, Mary E., Ponting, Chris P., Takahama, Yousuke, Holländer, Georg A.
Publicado 2016

Combined multidimensional single-cell protein and RNA profiling dissects the cellular and functional heterogeneity of thymic epithelial cells

por Klein, Fabian, Veiga-Villauriz, Clara, Börsch, Anastasiya, Maio, Stefano, Palmer, Sam, Dhalla, Fatima, Handel, Adam E., Zuklys, Saulius, Calvo-Asensio, Irene, Musette, Lucas, Deadman, Mary E., White, Andrea J., Lucas, Beth, Anderson, Graham, Holländer, Georg A.
Publicado 2023

The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function

por Oftedal, Bergithe E., Maio, Stefano, Handel, Adam E., White, Madeleine P. J., Howie, Duncan, Davis, Simon, Prevot, Nicolas, Rota, Ioanna A., Deadman, Mary E., Kessler, Benedikt M., Fischer, Roman, Trede, Nikolaus S., Sezgin, Erdinc, Maizels, Rick M., Holländer, Georg A.
Publicado 2021

Ageing compromises mouse thymus function and remodels epithelial cell differentiation

por Baran-Gale, Jeanette, Morgan, Michael D, Maio, Stefano, Dhalla, Fatima, Calvo-Asensio, Irene, Deadman, Mary E, Handel, Adam E, Maynard, Ashley, Chen, Steven, Green, Foad, Sit, Rene V, Neff, Norma F, Darmanis, Spyros, Tan, Weilun, May, Andy P, Marioni, John C, Ponting, Chris P, Holländer, Georg A
Publicado 2020

FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency

por Rota, Ioanna A., Handel, Adam E., Maio, Stefano, Klein, Fabian, Dhalla, Fatima, Deadman, Mary E., Cheuk, Stanley, Newman, Joseph A., Michaels, Yale S., Zuklys, Saulius, Prevot, Nicolas, Hublitz, Philip, Charles, Philip D., Gkazi, Athina Soragia, Adamopoulou, Eleni, Qasim, Waseem, Davies, Edward Graham, Hanson, Imelda, Pagnamenta, Alistair T., Camps, Carme, Dreau, Helene M., White, Andrea, James, Kieran, Fischer, Roman, Gileadi, Opher, Taylor, Jenny C., Fulga, Tudor, Lagerholm, B. Christoffer, Anderson, Graham, Sezgin, Erdinc, Holländer, Georg A.
Publicado 2021