New therapeutic approaches for Krabbe disease: The potential of pharmacological chaperones

por Spratley, Samantha J., Deane, Janet E.
Publicado 2016

Structure of human saposin A at lysosomal pH

por Hill, Chris H., Read, Randy J., Deane, Janet E.
Publicado 2015

Timing is everything: the regulation of type III secretion

por Deane, Janet E., Abrusci, Patrizia, Johnson, Steven, Lea, Susan M.
Publicado 2009

The lipid transfer protein Saposin B does not directly bind CD1d for lipid antigen loading

por Shamin, Maria, Benedyk, Tomasz H., Graham, Stephen C., Deane, Janet E.
Publicado 2019

A Tetrameric Assembly of Saposin A: Increasing Structural Diversity in Lipid Transfer Proteins

por Shamin, Maria, Spratley, Samantha J., Graham  , Stephen C., Deane , Janet E.
Publicado 2021

Structures of the Shigella flexneri Type 3 Secretion System Protein MxiC Reveal Conformational Variability Amongst Homologues

por Deane, Janet E., Roversi, Pietro, King, Carole, Johnson, Steven, Lea, Susan M.
Publicado 2008

The Shigella Virulence Factor IcsA Relieves N-WASP Autoinhibition by Displacing the Verprolin Homology/Cofilin/Acidic (VCA) Domain

por Mauricio, Rui P. M., Jeffries, Cy M., Svergun, Dmitri I., Deane, Janet E.
Publicado 2017

Expression, purification, crystallization and preliminary crystallographic analysis of BipD, a component of the Burkholderia pseudomallei type III secretion system

por Roversi, Pietro, Johnson, Steven, Field, Terry, Deane, Janet E., Galyov, Edouard E., Lea, Susan M.
Publicado 2006

Crystal structure of Spa40, the specificity switch for the Shigella flexneri type III secretion system

por Deane, Janet E, Graham, Stephen C, Mitchell, Edward P, Flot, David, Johnson, Steven, Lea, Susan M
Publicado 2008

The receptor PTPRU is a redox sensitive pseudophosphatase

por Hay, Iain M., Fearnley, Gareth W., Rios, Pablo, Köhn, Maja, Sharpe, Hayley J., Deane, Janet E.
Publicado 2020

Molecular Mechanisms of Disease Pathogenesis Differ in Krabbe Disease Variants

por Spratley, Samantha J., Hill, Chris H., Viuff, Agnete H., Edgar, James R., Skjødt, Karsten, Deane, Janet E.
Publicado 2016

The mechanism of glycosphingolipid degradation revealed by a GALC-SapA complex structure

por Hill, Chris H., Cook, Georgia M., Spratley, Samantha J., Fawke, Stuart, Graham, Stephen C., Deane, Janet E.
Publicado 2018

TAPBPR mediates peptide dissociation from MHC class I using a leucine lever

por Ilca, F Tudor, Neerincx, Andreas, Hermann, Clemens, Marcu, Ana, Stevanović, Stefan, Deane, Janet E, Boyle, Louise H
Publicado 2018

Molecular mechanism of Afadin substrate recruitment to the receptor phosphatase PTPRK via its pseudophosphatase domain

por Hay, Iain M, Mulholland, Katie E, Lai, Tiffany, Graham, Stephen C, Sharpe, Hayley J, Deane, Janet E
Publicado 2022

The crystal structure of vaccinia virus protein E2 and perspectives on the prediction of novel viral protein folds

por Gao, William N. D., Gao, Chen, Deane, Janet E., Carpentier, David C. J., Smith, Geoffrey L., Graham, Stephen C.
Publicado 2022

Insights into Hunter syndrome from the structure of iduronate-2-sulfatase

por Demydchuk, Mykhaylo, Hill, Chris H., Zhou, Aiwu, Bunkóczi, Gábor, Stein, Penelope E., Marchesan, Denis, Deane, Janet E., Read, Randy J.
Publicado 2017

Expression, purification, crystallization and preliminary crystallographic analysis of MxiH, a subunit of the Shigella flexneri type III secretion system needle

por Deane, Janet E., Cordes, Frank S., Roversi, Pietro, Johnson, Steven, Kenjale, Roma, Picking, William D., Picking, Wendy L., Lea, Susan M., Blocker, Ariel
Publicado 2006

Expression, limited proteolysis and preliminary crystallographic analysis of IpaD, a component of the Shigella flexneri type III secretion system

por Johnson, Steven, Roversi, Pietro, Espina, Marianela, Deane, Janet E., Birket, Susan, Picking, William D., Blocker, Ariel, Picking, Wendy L., Lea, Susan M.
Publicado 2006

Antagonism of PP2A is an independent and conserved function of HIV-1 Vif and causes cell cycle arrest

por Marelli, Sara, Williamson, James C, Protasio, Anna V, Naamati, Adi, Greenwood, Edward JD, Deane, Janet E, Lehner, Paul J, Matheson, Nicholas J
Publicado 2020

TAPBPR bridges UDP-glucose:glycoprotein glucosyltransferase 1 onto MHC class I to provide quality control in the antigen presentation pathway

por Neerincx, Andreas, Hermann, Clemens, Antrobus, Robin, van Hateren, Andy, Cao, Huan, Trautwein, Nico, Stevanović, Stefan, Elliott, Tim, Deane, Janet E, Boyle, Louise H
Publicado 2017