Randomised open label exploratory, safety and tolerability study with calmangafodipir in patients treated with the 12-h regimen of N-acetylcysteine for paracetamol overdose—the PP1...

por Dear, James
Publicado 2019

Fomepizole should not be used more liberally in paracetamol overdose

por Dear, James W.
Publicado 2022

Gastrointestinal AEs seen in the POP trial due to SOD mimetic activity of calmangafodipir? – Authors' reply

por Dear, James W.
Publicado 2019

Acetylcysteine in paracetamol poisoning: a perspective of 45 years of use

por Bateman, D. Nicholas, Dear, James W.
Publicado 2019

Are some people at increased risk of paracetamol-induced liver injury? A critical review of the literature

por Caparrotta, Thomas M., Antoine, Daniel J., Dear, James W.
Publicado 2017

Towards quantitative point of care detection using SERS lateral flow immunoassays

por Sloan-Dennison, Sian, O’Connor, Emma, Dear, James W., Graham, Duncan, Faulds, Karen
Publicado 2022

Response to the letter from Wong et al.

por Dear, James W., Dargan, Paul I., Eddleston, Michael, Thanacoody, Ruben H., Thomas, Simon H.L.
Publicado 2019

The conserved metalloprotease invadolysin is present in invertebrate haemolymph and vertebrate blood

por Abhinav, Kanishk, Feng, Linda, Morrison, Emma, Jung, Yunshin, Dear, James, Takahashi, Satoru, Heck, Margarete M. S.
Publicado 2019

MicroRNA‐122 can be measured in capillary blood which facilitates point‐of‐care testing for drug‐induced liver injury

por Vliegenthart, A. D. Bastiaan, Berends, Cécile, Potter, Carmelita M. J., Kersaudy‐Kerhoas, Maiwenn, Dear, James W.
Publicado 2017

Evaluation of plasma microRNA-122, high-mobility group box 1 and keratin-18 concentrations to stratify acute gallstone disease: a pilot observational cohort study in an emergency g...

por Th’ng, Francesca, Vliegenthart, Bastiaan, Lea, Jonathan D, Antoine, Daniel J, Dear, James W, Mole, Damian J
Publicado 2018

Investigation of a relationship between serum concentrations of microRNA-122 and alanine aminotransferase activity in hospitalised cats

por Armstrong, Susan K, Oosthuyzen, Wilna, Gow, Adam G, Salavati Schmitz, Silke, Dear, James W, Mellanby, Richard J
Publicado 2022

Functionality of primary hepatic non-parenchymal cells in a 3D spheroid model and contribution to acetaminophen hepatotoxicity

por Bell, Catherine C., Chouhan, Bhavik, Andersson, Linda C., Andersson, Håkan, Dear, James W., Williams, Dominic P., Söderberg, Magnus
Publicado 2020

Endothelin Receptor Antagonism Improves Lipid Profiles and Lowers PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) in Patients With Chronic Kidney Disease

por Farrah, Tariq E., Anand, Atul, Gallacher, Peter J., Kimmitt, Robert, Carter, Edwin, Dear, James W., Mills, Nicholas L., Webb, David J., Dhaun, Neeraj
Publicado 2019

A metabolomic analysis of thiol response for standard and modified N‐acetyl cysteine treatment regimens in patients with acetaminophen overdose

por Dear, James W, Ng, Mei Li, Bateman, D. Nicholas, Leroy Sivappiragasam, Pakkiri, Choi, Hyungwon, Khoo, Benjamin Bing Jie, Ibrahim, Baharudin, Drum, Chester Lee
Publicado 2021

Identification and proteomic profiling of exosomes in human cerebrospinal fluid

por Street, Jonathan M, Barran, Perdita E, Mackay, C Logan, Weidt, Stefan, Balmforth, Craig, Walsh, Tim S, Chalmers, Rod TA, Webb, David J, Dear, James W
Publicado 2012

Polymerase-free measurement of microRNA-122 with single base specificity using single molecule arrays: Detection of drug-induced liver injury

por Rissin, David M., López-Longarela, Barbara, Pernagallo, Salvatore, Ilyine, Hugh, Vliegenthart, A. D. Bastiaan, Dear, James W., Díaz-Mochón, Juan J., Duffy, David C.
Publicado 2017

MicroRNA‐122 and cytokeratin‐18 have potential as a biomarkers of drug‐induced liver injury in European and African patients on treatment for mycobacterial infection

por Rupprechter, Sarah A.E., Sloan, Derek J., Oosthuyzen, Wilna, Bachmann, Till T., Hill, Adam T., Dhaliwal, Kevin, Templeton, Kate, Matovu, Joshua, Sekaggya‐Wiltshire, Christine, Dear, James W.
Publicado 2021

Circulating Kidney Injury Molecule 1 Predicts Prognosis and Poor Outcome in Patients With Acetaminophen‐Induced Liver Injury

por Antoine, Daniel J., Sabbisetti, Venkata S., Francis, Ben, Jorgensen, Andrea L., Craig, Darren G.N., Simpson, Kenneth J., Bonventre, Joseph V., Park, B. Kevin, Dear, James W.
Publicado 2015

Scottish and Newcastle Antiemetic Pre-treatment for paracetamol poisoning study (SNAP)

por Thanacoody, H K Ruben, Gray, Alasdair, Dear, James W, Coyle, Judy, Sandilands, Euan A, Webb, David J, Lewis, Steff, Eddleston, Michael, Thomas, Simon HL, Bateman, D Nicholas
Publicado 2013

Principal results of a randomised open label exploratory, safety and tolerability study with calmangafodipir in patients treated with a 12 h regimen of N-acetylcysteine for paracet...

por Morrison, Emma E., Oatey, Katherine, Gallagher, Bernadette, Grahamslaw, Julia, O'Brien, Rachel, Black, Polly, Oosthuyzen, Wilna, Lee, Robert J., Weir, Christopher J., Henriksen, Dennis, Dear, James W.
Publicado 2019