The Role of Hypofractionated Radiotherapy in Prostate Cancer

por Benjamin, Linus C., Tree, Alison C., Dearnaley, David P.
Publicado 2017

Rationale and development of image-guided intensity-modulated radiotherapy post-prostatectomy: the present standard of care?

por Murray, Julia R, McNair, Helen A, Dearnaley, David P
Publicado 2015

Adjuvant therapy with oral sodium clodronate in locally advanced and metastatic prostate cancer: long-term overall survival results from the MRC PR04 and PR05 randomised controlled...

por Dearnaley, David P, Mason, Malcolm D, Parmar, Mahesh KB, Sanders, Karen, Sydes, Matthew R
Publicado 2009

Late Gastrointestinal Toxicity After Dose-Escalated Conformal Radiotherapy for Early Prostate Cancer: Results From the UK Medical Research Council RT01 Trial (ISRCTN47772397)

por Syndikus, Isabel, Morgan, Rachel C., Sydes, Matthew R., Graham, John D., Dearnaley, David P.
Publicado 2010

Symptom clusters for revising scale membership in the analysis of prostate cancer patient reported outcome measures: a secondary data analysis of the Medical Research Council RT01...

por Lemanska, Agnieszka, Chen, Tao, Dearnaley, David. P., Jena, Rajesh, Sydes, Matthew. R., Faithfull, Sara
Publicado 2017

Magnitude of observer error using cone beam CT for prostate interfraction motion estimation: effect of reducing scan length or increasing exposure

por McNair, Helen A, Harris, Emma J, Hansen, Vibeke N, Thomas, Karen, South, Christopher, Hafeez, Shaista, Huddart, Robert, Dearnaley, David P
Publicado 2015

Linking CHHiP prostate cancer RCT with GP records: A study proposal to investigate the effect of co-morbidities and medications on long-term symptoms and radiotherapy-related toxic...

por Lemanska, Agnieszka, Byford, Rachel C., Correa, Ana, Cruickshank, Clare, Dearnaley, David P., Griffin, Clare, Hall, Emma, de Lusignan, Simon, Faithfull, Sara
Publicado 2017

Impact of Pelvic Radiation Therapy for Prostate Cancer on Global Metabolic Profiles and Microbiota-Driven Gastrointestinal Late Side Effects: A Longitudinal Observational Study

por Ferreira, Miguel R., Sands, Caroline J., Li, Jia V., Andreyev, Jervoise N., Chekmeneva, Elena, Gulliford, Sarah, Marchesi, Julian, Lewis, Matthew R., Dearnaley, David P.
Publicado 2021

Issues in applying multi-arm multi-stage methodology to a clinical trial in prostate cancer: the MRC STAMPEDE trial

por Sydes, Matthew R, Parmar, Mahesh KB, James, Nicholas D, Clarke, Noel W, Dearnaley, David P, Mason, Malcolm D, Morgan, Rachel C, Sanders, Karen, Royston, Patrick
Publicado 2009

Ki67 Is an Independent Predictor of Recurrence in the Largest Randomized Trial of 3 Radiation Fractionation Schedules in Localized Prostate Cancer

por Wilkins, Anna C., Gusterson, Barry, Szijgyarto, Zsolt, Haviland, Joanne, Griffin, Clare, Stuttle, Christine, Daley, Frances, Corbishley, Catherine M., Dearnaley, David P., Hall, Emma, Somaiah, Navita
Publicado 2018

Bone lesion absorbed dose profiles in patients with metastatic prostate cancer treated with molecular radiotherapy

por Denis-Bacelar, Ana M, Chittenden, Sarah J, McCready, V Ralph, Divoli, Antigoni, Dearnaley, David P, O’Sullivan, Joe M, Johnson, Bernadette, Flux, Glenn D
Publicado 2018

Linkage of the CHHiP randomised controlled trial with primary care data: a study investigating ways of supplementing cancer trials and improving evidence-based practice

por Lemanska, Agnieszka, Byford, Rachel C., Cruickshank, Clare, Dearnaley, David P., Ferreira, Filipa, Griffin, Clare, Hall, Emma, Hinton, William, de Lusignan, Simon, Sherlock, Julian, Faithfull, Sara
Publicado 2020

Gastrointestinal Toxicity Prediction Not Influenced by Rectal Contour or Dose-Volume Histogram Definition

por Brand, Douglas H., Brüningk, Sarah C., Wilkins, Anna, Naismith, Olivia, Gao, Annie, Syndikus, Isabel, Dearnaley, David P., Hall, Emma, van As, Nicholas, Tree, Alison C., Gulliford, Sarah
Publicado 2023

Phase I/II trials of (186)Re-HEDP in metastatic castration-resistant prostate cancer: post-hoc analysis of the impact of administered activity and dosimetry on survival

por Denis-Bacelar, Ana M., Chittenden, Sarah J., Dearnaley, David P., Divoli, Antigoni, O’Sullivan, Joe M., McCready, V. Ralph, Johnson, Bernadette, Du, Yong, Flux, Glenn D.
Publicado 2016

A radiobiological model of metastatic burden reduction for molecular radiotherapy: application to patients with bone metastases

por Denis-Bacelar, Ana M, Chittenden, Sarah J, Murray, Iain, Divoli, Antigoni, Ralph McCready, V, Dearnaley, David P, O’Sullivan, Joe M, Johnson, Bernadette, Flux, Glenn D
Publicado 2017

Estimates of Alpha/Beta (α/β) Ratios for Individual Late Rectal Toxicity Endpoints: An Analysis of the CHHiP Trial

por Brand, Douglas H., Brüningk, Sarah C., Wilkins, Anna, Fernandez, Katie, Naismith, Olivia, Gao, Annie, Syndikus, Isabel, Dearnaley, David P., Tree, Alison C., van As, Nicholas, Hall, Emma, Gulliford, Sarah
Publicado 2021

Phase 1/2 Dose-Escalation Study of the Use of Intensity Modulated Radiation Therapy to Treat the Prostate and Pelvic Nodes in Patients With Prostate Cancer

por Reis Ferreira, Miguel, Khan, Atia, Thomas, Karen, Truelove, Lesley, McNair, Helen, Gao, Annie, Parker, Chris C., Huddart, Robert, Bidmead, Margaret, Eeles, Ros, Khoo, Vincent, van As, Nicholas J., Hansen, Vibeke N., Dearnaley, David P.
Publicado 2017

Flexible trial design in practice – dropping and adding arms in STAMPEDE: a multi-arm multi-stage randomised controlled trial

por Sydes, Matthew R, James, Nicholas D, Mason, Malcolm D, Clarke, Noel W, Amos, Claire, Anderson, John, de Bono, Johann, Dearnaley, David P, Dwyer, John, Jovic, Gordana, Ritchie, Alastair, Russell, Martin, Sanders, Karen, Thalmann, George, Parmar, Mahesh KB
Publicado 2011

Flexible trial design in practice - stopping arms for lack-of-benefit and adding research arms mid-trial in STAMPEDE: a multi-arm multi-stage randomized controlled trial

por Sydes, Matthew R, Parmar, Mahesh KB, Mason, Malcolm D, Clarke, Noel W, Amos, Claire, Anderson, John, de Bono, Johann, Dearnaley, David P, Dwyer, John, Green, Charlene, Jovic, Gordana, Ritchie, Alastair WS, Russell, J Martin, Sanders, Karen, Thalmann, George, James, Nicholas D
Publicado 2012

Common genetic variation associated with increased susceptibility to prostate cancer does not increase risk of radiotherapy toxicity

por Ahmed, Mahbubl, Dorling, Leila, Kerns, Sarah, Fachal, Laura, Elliott, Rebecca, Partliament, Matt, Rosenstein, Barry S, Vega, Ana, Gómez-Caamaño, Antonio, Barnett, Gill, Dearnaley, David P, Hall, Emma, Sydes, Matt, Burnet, Neil, Pharoah, Paul D P, Eeles, Ros, West, Catharine M L
Publicado 2016