Oxidative Stress-Inducing Anticancer Therapies: Taking a Closer Look at Their Immunomodulating Effects

por Van Loenhout, Jinthe, Peeters, Marc, Bogaerts, Annemie, Smits, Evelien, Deben, Christophe
Publicado 2020

Cellular senescence in cancer: clinical detection and prognostic implications

por Domen, Andreas, Deben, Christophe, Verswyvel, Jasper, Flieswasser, Tal, Prenen, Hans, Peeters, Marc, Lardon, Filip, Wouters, An
Publicado 2022

Characterization of acquired nutlin-3 resistant non-small cell lung cancer cells

por Deben, Christophe, Boullosa, Laurie Freire, Domen, Andreas, Wouters, An, Cuypers, Bart, Laukens, Kris, Lardon, Filip, Pauwels, Patrick
Publicado 2021

Mass Spectrometry Imaging Reveals Neutrophil Defensins as Additional Biomarkers for Anti-PD-(L)1 Immunotherapy Response in NSCLC Patients

por Berghmans, Eline, Jacobs, Julie, Deben, Christophe, Hermans, Christophe, Broeckx, Glenn, Smits, Evelien, Maes, Evelyne, Raskin, Jo, Pauwels, Patrick, Baggerman, Geert
Publicado 2020

The Influence of Cell Type and Culture Medium on Determining Cancer Selectivity of Cold Atmospheric Plasma Treatment

por Biscop, Eline, Lin, Abraham, Van Boxem, Wilma, Van Loenhout, Jinthe, De Backer, Joey, Deben, Christophe, Dewilde, Sylvia, Smits, Evelien, Bogaerts, Annemie
Publicado 2019

Better to be alone than in bad company: The antagonistic effect of cisplatin and crizotinib combination therapy in non-small cell lung cancer

por Van Der Steen, Nele, Deben, Christophe, Deschoolmeester, Vanessa, Wouters, An, Lardon, Filip, Rolfo, Christian, Germonpré, Paul, Giovannetti, Elisa, Peters, Godefridus J, Pauwels, Patrick
Publicado 2016

Hypoxia-Induced Cisplatin Resistance in Non-Small Cell Lung Cancer Cells Is Mediated by HIF-1α and Mutant p53 and Can Be Overcome by Induction of Oxidative Stress

por Deben, Christophe, Deschoolmeester, Vanessa, De Waele, Jorrit, Jacobs, Julie, Van den Bossche, Jolien, Wouters, An, Peeters, Marc, Rolfo, Christian, Smits, Evelien, Lardon, Filip, Pauwels, Patrick
Publicado 2018

UAS™—A Urine Preservative for Oncology Applications

por Jordaens, Stephanie, Arora, Amit, MacDonald, Kyle W., Wood, Cameron, Hendrickx, Jhana O., Zwaenepoel, Karen, Deben, Christophe, Tjalma, Wiebren, Pauwels, Patrick, Beyers, Koen, Vankerckhoven, Vanessa
Publicado 2023

MDM2 SNP309 and SNP285 Act as Negative Prognostic Markers for Non-small Cell Lung Cancer Adenocarcinoma Patients

por Deben, Christophe, Op de Beeck, Ken, Van den Bossche, Jolien, Jacobs, Julie, Lardon, Filip, Wouters, An, Peeters, Marc, Van Camp, Guy, Rolfo, Christian, Deschoolmeester, Vanessa, Pauwels, Patrick
Publicado 2017

Unlocking the potential of CD70 as a novel immunotherapeutic target for non-small cell lung cancer

por Jacobs, Julie, Zwaenepoel, Karen, Rolfo, Christian, Van den Bossche, Jolien, Deben, Christophe, Silence, Karen, Hermans, Christophe, Smits, Evelien, Van Schil, Paul, Lardon, Filip, Deschoolmeester, Vanessa, Pauwels, Patrick
Publicado 2015

The MDM2-inhibitor Nutlin-3 synergizes with cisplatin to induce p53 dependent tumor cell apoptosis in non-small cell lung cancer

por Deben, Christophe, Wouters, An, de Beeck, Ken Op, van Den Bossche, Jolien, Jacobs, Julie, Zwaenepoel, Karen, Peeters, Marc, Van Meerbeeck, Jan, Lardon, Filip, Rolfo, Christian, Deschoolmeester, Vanessa, Pauwels, Patrick
Publicado 2015

Radiosensitization of Non-Small Cell Lung Cancer Cells by the Plk1 Inhibitor Volasertib Is Dependent on the p53 Status

por Van den Bossche, Jolien, Domen, Andreas, Peeters, Marc, Deben, Christophe, De Pauw, Ines, Jacobs, Julie, De Bruycker, Sven, Specenier, Pol, Pauwels, Patrick, Vermorken, Jan Baptist, Lardon, Filip, Wouters, An
Publicado 2019

In vitro study of the Polo‐like kinase 1 inhibitor volasertib in non‐small‐cell lung cancer reveals a role for the tumor suppressor p53

por Van den Bossche, Jolien, Deben, Christophe, De Pauw, Ines, Lambrechts, Hilde, Hermans, Christophe, Deschoolmeester, Vanessa, Jacobs, Julie, Specenier, Pol, Pauwels, Patrick, Vermorken, Jan Baptist, Peeters, Marc, Lardon, Filip, Wouters, An
Publicado 2019

Functional Validation of the Putative Oncogenic Activity of PLAU

por Sarno, Federica, Goubert, Désirée, Logie, Emilie, Rutten, Martijn G. S., Koncz, Mihaly, Deben, Christophe, Niemarkt, Anita E., Altucci, Lucia, Verschure, Pernette J., Kiss, Antal, Berghe, Wim Vanden, Rots, Marianne G.
Publicado 2022

Auranofin Synergizes with the PARP Inhibitor Olaparib to Induce ROS-Mediated Cell Death in Mutant p53 Cancers

por Freire Boullosa, Laurie, Van Loenhout, Jinthe, Flieswasser, Tal, Hermans, Christophe, Merlin, Céline, Lau, Ho Wa, Marcq, Elly, Verschuuren, Marlies, De Vos, Winnok H., Lardon, Filip, Smits, Evelien L. J., Deben, Christophe
Publicado 2023

Preclinical data on the combination of cisplatin and anti-CD70 therapy in non-small cell lung cancer as an excellent match in the era of combination therapy

por Jacobs, Julie, Deschoolmeester, Vanessa, Rolfo, Christian, Zwaenepoel, Karen, Van den Bossche, Jolien, Deben, Christophe, Silence, Karen, de Haard, Hans, Hermans, Christophe, Rottey, Sylvie, Vangestel, Christel, Lardon, Filip, Smits, Evelien, Pauwels, Patrick
Publicado 2017

Cancer-Associated Fibroblasts as a Common Orchestrator of Therapy Resistance in Lung and Pancreatic Cancer

por Domen, Andreas, Quatannens, Delphine, Zanivan, Sara, Deben, Christophe, Van Audenaerde, Jonas, Smits, Evelien, Wouters, An, Lardon, Filip, Roeyen, Geert, Verhoeven, Yannick, Janssens, Annelies, Vandamme, Timon, van Dam, Peter, Peeters, Marc, Prenen, Hans
Publicado 2021

Towards Prognostic Profiling of Non-Small Cell Lung Cancer: New Perspectives on the Relevance of Polo-Like Kinase 1 Expression, the TP53 Mutation Status and Hypoxia

por Van den Bossche, Jolien, Deben, Christophe, Op de Beeck, Ken, Deschoolmeester, Vanessa, Hermans, Christophe, De Pauw, Ines, Jacobs, Julie, Van Schil, Paul, Vermorken, Jan Baptist, Pauwels, Patrick, Peeters, Marc, Lardon, Filip, Wouters, An
Publicado 2017

Auranofin and Cold Atmospheric Plasma Synergize to Trigger Distinct Cell Death Mechanisms and Immunogenic Responses in Glioblastoma

por Van Loenhout, Jinthe, Freire Boullosa, Laurie, Quatannens, Delphine, De Waele, Jorrit, Merlin, Céline, Lambrechts, Hilde, Lau, Ho Wa, Hermans, Christophe, Lin, Abraham, Lardon, Filip, Peeters, Marc, Bogaerts, Annemie, Smits, Evelien, Deben, Christophe
Publicado 2021

Optimization of the Solvent and In Vivo Administration Route of Auranofin in a Syngeneic Non-Small Cell Lung Cancer and Glioblastoma Mouse Model

por Freire Boullosa, Laurie, Van Loenhout, Jinthe, Hermans, Christophe, Lau, Ho Wa, Merlin, Céline, Marcq, Elly, Takhsha, Farnaz Sedigheh, Martinet, Wim, De Meyer, Guido R. Y., Lardon, Filip, Smits, Evelien L. J., Deben, Christophe
Publicado 2022