The CRF Family of Neuropeptides and their Receptors - Mediators of the Central Stress Response

por Dedic, Nina, Chen, Alon, Deussing, Jan M.
Publicado 2018

Effect of TAAR1/5-HT(1A) agonist SEP-363856 on REM sleep in humans

por Hopkins, Seth C., Dedic, Nina, Koblan, Kenneth S.
Publicado 2021

Therapeutic Potential of TAAR1 Agonists in Schizophrenia: Evidence from Preclinical Models and Clinical Studies

por Dedic, Nina, Dworak, Heather, Zeni, Courtney, Rutigliano, Grazia, Howes, Oliver D.
Publicado 2021

Ulotaront: review of preliminary evidence for the efficacy and safety of a TAAR1 agonist in schizophrenia

por Achtyes, Eric D., Hopkins, Seth C., Dedic, Nina, Dworak, Heather, Zeni, Courtney, Koblan, Kenneth
Publicado 2023

In Vitro ADME and Preclinical Pharmacokinetics of Ulotaront, a TAAR1/5-HT(1A) Receptor Agonist for the Treatment of Schizophrenia

por Xiao, Guangqing, Chen, Yu-Luan, Dedic, Nina, Xie, Linghong, Koblan, Kenneth S., Galluppi, Gerald R.
Publicado 2022

Deletion of CRH From GABAergic Forebrain Neurons Promotes Stress Resilience and Dampens Stress-Induced Changes in Neuronal Activity

por Dedic, Nina, Kühne, Claudia, Gomes, Karina S., Hartmann, Jakob, Ressler, Kerry J., Schmidt, Mathias V., Deussing, Jan M.
Publicado 2019

Genetically dissecting P2rx7 expression within the central nervous system using conditional humanized mice

por Metzger, Michael W., Walser, Sandra M., Aprile-Garcia, Fernando, Dedic, Nina, Chen, Alon, Holsboer, Florian, Arzt, Eduardo, Wurst, Wolfgang, Deussing, Jan M.
Publicado 2016

Activation of CRH receptor type 1 expressed on glutamatergic neurons increases excitability of CA1 pyramidal neurons by the modulation of voltage-gated ion channels

por Kratzer, Stephan, Mattusch, Corinna, Metzger, Michael W., Dedic, Nina, Noll-Hussong, Michael, Kafitz, Karl W., Eder, Matthias, Deussing, Jan M., Holsboer, Florian, Kochs, Eberhard, Rammes, Gerhard
Publicado 2013

Noninvasive Deep Brain Stimulation via Temporally Interfering Electric Fields

por Grossman, Nir, Bono, David, Dedic, Nina, Kodandaramaiah, Suhasa B., Rudenko, Andrii, Suk, Ho-Jun, Cassara, Antonino M., Neufeld, Esra, Kuster, Niels, Tsai, Li-Huei, Pascual-Leone, Alvaro, Boyden, Edward S.
Publicado 2017

Ulotaront: A TAAR1 Agonist for the Treatment of Schizophrenia

por Heffernan, Michele L. R., Herman, Lee W., Brown, Scott, Jones, Philip G., Shao, Liming, Hewitt, Michael C., Campbell, John E., Dedic, Nina, Hopkins, Seth C., Koblan, Kenneth S., Xie, Linghong
Publicado 2021

Reproducing the dopamine pathophysiology of schizophrenia and approaches to ameliorate it: a translational imaging study with ketamine

por Kokkinou, Michelle, Irvine, Elaine E., Bonsall, David R., Natesan, Sridhar, Wells, Lisa A., Smith, Mark, Glegola, Justyna, Paul, Eleanor J., Tossell, Kyoko, Veronese, Mattia, Khadayate, Sanjay, Dedic, Nina, Hopkins, Seth C., Ungless, Mark A., Withers, Dominic J., Howes, Oliver D.
Publicado 2020

Association of FKBP51 with Priming of Autophagy Pathways and Mediation of Antidepressant Treatment Response: Evidence in Cells, Mice, and Humans

por Gassen, Nils C., Hartmann, Jakob, Zschocke, Jürgen, Stepan, Jens, Hafner, Kathrin, Zellner, Andreas, Kirmeier, Thomas, Kollmannsberger, Lorenz, Wagner, Klaus V., Dedic, Nina, Balsevich, Georgia, Deussing, Jan M., Kloiber, Stefan, Lucae, Susanne, Holsboer, Florian, Eder, Matthias, Uhr, Manfred, Ising, Marcus, Schmidt, Mathias V., Rein, Theo
Publicado 2014

Mineralocorticoid receptors dampen glucocorticoid receptor sensitivity to stress via regulation of FKBP5

por Hartmann, Jakob, Bajaj, Thomas, Klengel, Claudia, Chatzinakos, Chris, Ebert, Tim, Dedic, Nina, McCullough, Kenneth M., Lardenoije, Roy, Joëls, Marian, Meijer, Onno C., McCann, Katharine E., Dudek, Serena M., Sarabdjitsingh, R. Angela, Daskalakis, Nikolaos P., Klengel, Torsten, Gassen, Nils C., Schmidt, Mathias V., Ressler, Kerry J.
Publicado 2021