Phosphopeptide binding by Sld3 links Dbf4‐dependent kinase to MCM replicative helicase activation

por Deegan, Tom D, Yeeles, Joseph TP, Diffley, John FX
Publicado 2016

CMG helicase disassembly is controlled by replication fork DNA, replisome components and a ubiquitin threshold

por Deegan, Tom D, Mukherjee, Progya P, Fujisawa, Ryo, Polo Rivera, Cristian, Labib, Karim
Publicado 2020

TIMELESS‐TIPIN and UBXN‐3 promote replisome disassembly during DNA replication termination in Caenorhabditis elegans

por Xia, Yisui, Fujisawa, Ryo, Deegan, Tom D, Sonneville, Remi, Labib, Karim P M
Publicado 2021

Regulated Eukaryotic DNA Replication Origin Firing with Purified Proteins

por Yeeles, Joseph T.P., Deegan, Tom D., Janska, Agnieszka, Early, Anne, Diffley, John F. X.
Publicado 2015

Pif1-Family Helicases Support Fork Convergence during DNA Replication Termination in Eukaryotes

por Deegan, Tom D., Baxter, Jonathan, Ortiz Bazán, María Ángeles, Yeeles, Joseph T.P., Labib, Karim P.M.
Publicado 2019

A conserved mechanism for regulating replisome disassembly in eukaryotes

por Jenkyn-Bedford, Michael, Jones, Morgan L., Baris, Yasemin, Labib, Karim P. M., Cannone, Giuseppe, Yeeles, Joseph T. P., Deegan, Tom D.
Publicado 2021

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp15 endoribonuclease

por Canal, Berta, Fujisawa, Ryo, McClure, Allison W., Deegan, Tom D., Wu, Mary, Ulferts, Rachel, Weissmann, Florian, Drury, Lucy S., Bertolin, Agustina P., Zeng, Jingkun, Beale, Rupert, Howell, Michael, Labib, Karim, Diffley, John F.X.
Publicado 2021

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp14/nsp10 exoribonuclease

por Canal, Berta, McClure, Allison W., Curran, Joseph F., Wu, Mary, Ulferts, Rachel, Weissmann, Florian, Zeng, Jingkun, Bertolin, Agustina P., Milligan, Jennifer C., Basu, Souradeep, Drury, Lucy S., Deegan, Tom D., Fujisawa, Ryo, Roberts, Emma L., Basier, Clovis, Labib, Karim, Beale, Rupert, Howell, Michael, Diffley, John F.X.
Publicado 2021

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase

por Basu, Souradeep, Mak, Tiffany, Ulferts, Rachel, Wu, Mary, Deegan, Tom, Fujisawa, Ryo, Tan, Kang Wei, Lim, Chew Theng, Basier, Clovis, Canal, Berta, Curran, Joseph F., Drury, Lucy S., McClure, Allison W., Roberts, Emma L., Weissmann, Florian, Zeisner, Theresa U., Beale, Rupert, Cowling, Victoria H., Howell, Michael, Labib, Karim, Diffley, John F.X.
Publicado 2021

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp5 main protease

por Milligan, Jennifer C., Zeisner, Theresa U., Papageorgiou, George, Joshi, Dhira, Soudy, Christelle, Ulferts, Rachel, Wu, Mary, Lim, Chew Theng, Tan, Kang Wei, Weissmann, Florian, Canal, Berta, Fujisawa, Ryo, Deegan, Tom, Nagaraj, Hema, Bineva-Todd, Ganka, Basier, Clovis, Curran, Joseph F., Howell, Michael, Beale, Rupert, Labib, Karim, O'Reilly, Nicola, Diffley, John F.X.
Publicado 2021