Searching for the genetic key to a long and healthy life

por Deelen, Joris
Publicado 2020

Targeting multimorbidity: Using healthspan and lifespan to identify biomarkers of ageing that pinpoint shared disease mechanisms

por Deelen, Joris
Publicado 2021

Challenges in anti‐aging medicine–trends in biomarker discovery and therapeutic interventions for a healthy lifespan

por Popescu, Iuliana, Deelen, Joris, Illario, Maddalena, Adams, Jan
Publicado 2023

Editorial: Mechanisms and Pathways Contributing to the Diversity of Aging Across the Tree of Life

por Cohen, Alan A., Deelen, Joris, Jones, Owen R.
Publicado 2022

From mutation to mechanism: deciphering the molecular function of genetic variants linked to human ageing

por Baghdadi, Maarouf, Hinterding, Helena M, Partridge, Linda, Deelen, Joris
Publicado 2021

Identifying the genomic determinants of aging and longevity in human population studies: Progress and challenges

por Deelen, Joris, Beekman, Marian, Capri, Miriam, Franceschi, Claudio, Slagboom, P Eline
Publicado 2013

Multivariate genomic scan implicates novel loci and haem metabolism in human ageing

por Timmers, Paul R. H. J., Wilson, James F., Joshi, Peter K., Deelen, Joris
Publicado 2020

Convergent genomics of longevity in rockfishes highlights the genetics of human life span variation

por Treaster, Stephen, Deelen, Joris, Daane, Jacob M., Murabito, Joanne, Karasik, David, Harris, Matthew P.
Publicado 2023

Assessment of the contribution of APOE gene variants to metabolic phenotypes associated with familial longevity at middle age

por Noordam, Raymond, Oudt, Charlotte H., Deelen, Joris, Slagboom, P. Eline, Beekman, Marian, van Heemst, Diana
Publicado 2016

Correlation of the two most frequent HLA haplotypes in the Italian population to the differential regional incidence of Covid-19

por Pisanti, Simona, Deelen, Joris, Gallina, Anna Maria, Caputo, Mariella, Citro, Marianna, Abate, Mario, Sacchi, Nicoletta, Vecchione, Carmine, Martinelli, Rosanna
Publicado 2020

Fibroblast growth factor 21 reflects liver fat accumulation and dysregulation of signalling pathways in the liver of C57BL/6J mice

por Rusli, Fenni, Deelen, Joris, Andriyani, Evi, Boekschoten, Mark V., Lute, Carolien, van den Akker, Erik B., Müller, Michael, Beekman, Marian, Steegenga, Wilma T
Publicado 2016

Estimation of metabolite networks with regard to a specific covariable: applications to plant and human data

por Bartzis, Georgios, Deelen, Joris, Maia, Julio, Ligterink, Wilco, Hilhorst, Henk W. M., Houwing-Duistermaat, Jeanine-J., van Eeuwijk, Fred, Uh, Hae-Won
Publicado 2017

Similar burden of pathogenic coding variants in exceptionally long‐lived individuals and individuals without exceptional longevity

por Gutman, Danielle, Lidzbarsky, Gabriel, Milman, Sofiya, Gao, Tina, Sin-Chan, Patrick, Gonzaga‐Jauregui, Claudia, Deelen, Joris, Shuldiner, Alan R., Barzilai, Nir, Atzmon, Gil
Publicado 2020

Copy number variation associates with mortality in long‐lived individuals: a genome‐wide assessment

por Nygaard, Marianne, Debrabant, Birgit, Tan, Qihua, Deelen, Joris, Andersen‐Ranberg, Karen, de Craen, Anton J.M., Beekman, Marian, Jeune, Bernard, Slagboom, Pieternella E., Christensen, Kaare, Christiansen, Lene
Publicado 2015

The effect of standardized food intake on the association between BMI and (1)H-NMR metabolites

por Schutte, Bianca A. M., van den Akker, Erik B., Deelen, Joris, van de Rest, Ondine, van Heemst, Diana, Feskens, Edith J. M., Beekman, Marian, Slagboom, P. Eline
Publicado 2016

How to deal with the early GWAS data when imputing and combining different arrays is necessary

por Uh, Hae-Won, Deelen, Joris, Beekman, Marian, Helmer, Quinta, Rivadeneira, Fernando, Hottenga, Jouke-Jan, Boomsma, Dorret I, Hofman, Albert, Uitterlinden, André G, Slagboom, P E, Böhringer, Stefan, Houwing-Duistermaat, Jeanine J
Publicado 2012

Association between the rs7903146 Polymorphism in the TCF7L2 Gene and Parameters Derived with Continuous Glucose Monitoring in Individuals without Diabetes

por van der Kroef, Sabrina, Noordam, Raymond, Deelen, Joris, Akintola, Abimbola A., Jansen, Steffy W. M., Postmus, Iris, Wijsman, Carolien A., Beekman, Marian, Mooijaart, Simon P., Slagboom, P. Eline, van Heemst, Diana
Publicado 2016

Non-Homologous End-Joining Pathway Associated with Occurrence of Myocardial Infarction: Gene Set Analysis of Genome-Wide Association Study Data

por Verschuren, Jeffrey J. W., Trompet, Stella, Deelen, Joris, Stott, David J., Sattar, Naveed, Buckley, Brendan M., Ford, Ian, Heijmans, Bastiaan T., Guchelaar, Henk-Jan, Houwing-Duistermaat, Jeanine J., Slagboom, P. Eline, Jukema, J. Wouter
Publicado 2013

Lifestyle‐Intervention‐Induced Reduction of Abdominal Fat Is Reflected by a Decreased Circulating Glycerol Level and an Increased HDL Diameter

por Beekman, Marian, Schutte, Bianca A.M., van den Akker, Erik B., Noordam, Raymond, Dibbets‐Schneider, Petra, de Geus‐Oei, Lioe‐Fee, Deelen, Joris, van de Rest, Ondine, van Heemst, Diana, Feskens, Edith J.M., Slagboom, P. Eline
Publicado 2020

IL7R gene expression network associates with human healthy ageing

por Passtoors, Willemijn M., van den Akker, Erik B., Deelen, Joris, Maier, Andrea B., van der Breggen, Ruud, Jansen, Rick, Trompet, Stella, van Heemst, Diana, Derhovanessian, Evelyna, Pawelec, Graham, van Ommen, Gert-Jan B., Slagboom, P. Eline, Beekman, Marian
Publicado 2015