Sequence-specific recognition of methylated DNA by human zinc-finger proteins

por Sasai, Nobuhiro, Nakao, Mitsuyoshi, Defossez, Pierre-Antoine
Publicado 2010

On how mammalian transcription factors recognize methylated DNA

por Buck-Koehntop, Bethany A., Defossez, Pierre-Antoine
Publicado 2013

Context-dependent CpG methylation directs cell-specific binding of transcription factor ZBTB38

por Marchal, Claire, Defossez, Pierre-Antoine, Miotto, Benoit
Publicado 2022

Staying true to yourself: mechanisms of DNA methylation maintenance in mammals

por Petryk, Nataliya, Bultmann, Sebastian, Bartke, Till, Defossez, Pierre-Antoine
Publicado 2020

Mechanisms of DNA Methyltransferase Recruitment in Mammals

por Laisné, Marthe, Gupta, Nikhil, Kirsh, Olivier, Pradhan, Sriharsa, Defossez, Pierre-Antoine
Publicado 2018

Large-Scale Chromatin Rearrangements in Cancer

por Yamaguchi, Kosuke, Chen, Xiaoying, Oji, Asami, Hiratani, Ichiro, Defossez, Pierre-Antoine
Publicado 2022

Screening of a kinase library reveals novel pro-senescence kinases and their common NF-κB-dependent transcriptional program

por Ferrand, Mylène, Kirsh, Olivier, Griveau, Audrey, Vindrieux, David, Martin, Nadine, Defossez, Pierre-Antoine, Bernard, David
Publicado 2015

Unchanged PCNA and DNMT1 dynamics during replication in DNA ligase I-deficient cells but abnormal chromatin levels of non-replicative histone H1

por Bhandari, Seema Khattri, Wiest, Nathaniel, Sallmyr, Annahita, Du, Ruofei, Ferry, Laure, Defossez, Pierre-Antoine, Tomkinson, Alan E.
Publicado 2023

The nuclear receptor RXRA controls cellular senescence by regulating calcium signaling

por Ma, Xingjie, Warnier, Marine, Raynard, Clotilde, Ferrand, Mylène, Kirsh, Olivier, Defossez, Pierre‐Antoine, Martin, Nadine, Bernard, David
Publicado 2018

MBD4 cooperates with DNMT1 to mediate methyl-DNA repression and protects mammalian cells from oxidative stress

por Laget, Sophie, Miotto, Benoit, Chin, Hang Gyeong, Estève, Pierre-Olivier, Roberts, Richard J, Pradhan, Sriharsa, Defossez, Pierre-Antoine
Publicado 2014

Stabilization of the methyl-CpG binding protein ZBTB38 by the deubiquitinase USP9X limits the occurrence and toxicity of oxidative stress in human cells

por Miotto, Benoit, Marchal, Claire, Adelmant, Guillaume, Guinot, Nadège, Xie, Ping, Marto, Jarrod A, Zhang, Lingqiang, Defossez, Pierre-Antoine
Publicado 2018

The Human Proteins MBD5 and MBD6 Associate with Heterochromatin but They Do Not Bind Methylated DNA

por Laget, Sophie, Joulie, Michael, Le Masson, Florent, Sasai, Nobuhiro, Christians, Elisabeth, Pradhan, Sriharsa, Roberts, Richard J., Defossez, Pierre-Antoine
Publicado 2010

Depletion of ZBTB38 potentiates the effects of DNA demethylating agents in cancer cells via CDKN1C mRNA up-regulation

por Marchal, Claire, de Dieuleveult, Maud, Saint-Ruf, Claude, Guinot, Nadège, Ferry, Laure, Olalla Saad, Sara T., Lazarini, Mariana, Defossez, Pierre-Antoine, Miotto, Benoit
Publicado 2018

IDENTIFICATION OF ONCOGENIC MicroRNA-17-92/ZBTB4/SPECIFICITY PROTEIN AXIS IN BREAST CANCER

por Kim, Kyounghyun, Chadalapaka, Gayathri, Lee, Syng-ook, Yamada, Daisuke, Sastre-Garau, Xavier, Defossez, Pierre-Antoine, Park, Yun-Yong, Lee, Ju-Seog, Safe, Stephen
Publicado 2011

MyoD reprogramming requires Six1 and Six4 homeoproteins: genome-wide cis-regulatory module analysis

por Santolini, Marc, Sakakibara, Iori, Gauthier, Morgane, Ribas-Aulinas, Francesc, Takahashi, Hirotaka, Sawasaki, Tatsuya, Mouly, Vincent, Concordet, Jean-Paul, Defossez, Pierre-Antoine, Hakim, Vincent, Maire, Pascal
Publicado 2016

Genetic screens reveal mechanisms for the transcriptional regulation of tissue-specific genes in normal cells and tumors

por Naciri, Ikrame, Laisné, Marthe, Ferry, Laure, Bourmaud, Morgane, Gupta, Nikhil, Di Carlo, Selene, Huna, Anda, Martin, Nadine, Peduto, Lucie, Bernard, David, Kirsh, Olivier, Defossez, Pierre-Antoine
Publicado 2019

RSK3 switches cell fate: from stress-induced senescence to malignant progression

por Huna, Anda, Flaman, Jean-Michel, Lodillinsky, Catalina, Zhu, Kexin, Makulyte, Gabriela, Pakulska, Victoria, Coute, Yohann, Ruisseaux, Clémence, Saintigny, Pierre, Hernandez-Vargas, Hector, Defossez, Pierre-Antoine, Boissan, Mathieu, Martin, Nadine, Bernard, David
Publicado 2023

Structural basis for activation of DNMT1

por Kikuchi, Amika, Onoda, Hiroki, Yamaguchi, Kosuke, Kori, Satomi, Matsuzawa, Shun, Chiba, Yoshie, Tanimoto, Shota, Yoshimi, Sae, Sato, Hiroki, Yamagata, Atsushi, Shirouzu, Mikako, Adachi, Naruhiko, Sharif, Jafar, Koseki, Haruhiko, Nishiyama, Atsuya, Nakanishi, Makoto, Defossez, Pierre-Antoine, Arita, Kyohei
Publicado 2022

A genetic screen identifies BEND3 as a regulator of bivalent gene expression and global DNA methylation

por Yakhou, Lounis, Azogui, Anaelle, Gupta, Nikhil, Richard Albert, Julien, Miura, Fumihito, Ferry, Laure, Yamaguchi, Kosuke, Battault, Sarah, Therizols, Pierre, Bonhomme, Frédéric, Bethuel, Elouan, Sarkar, Arpita, Greenberg, Maxim V C, Arimondo, Paola B, Cristofari, Gael, Kirsh, Olivier, Ito, Takashi, Defossez, Pierre-Antoine
Publicado 2023