Androgen receptor: Functional roles and facets of regulation in urology

por Dehm, Scott M., Huang, Haojie
Publicado 2020

Biomarker-Based Targeting of the Androgen-Androgen Receptor Axis in Advanced Prostate Cancer

por Kohli, Manish, Qin, Rui, Jimenez, Rafael, Dehm, Scott M.
Publicado 2012

Indel detection from DNA and RNA sequencing data with transIndel

por Yang, Rendong, Van Etten, Jamie L., Dehm, Scott M.
Publicado 2018

SHEAR: sample heterogeneity estimation and assembly by reference

por Landman, Sean R, Hwang, Tae Hyun, Silverstein, Kevin AT, Li, Yingming, Dehm, Scott M, Steinbach, Michael, Kumar, Vipin
Publicado 2014

Exploiting the transcriptional specificity of the alpha-methylacyl-CoA racemase AMACR promoter for the molecular imaging of prostate cancer

por Shapovalova, Mariya, Davydova, Julia, Henzler, Christine, Daniel, Mark, Dehm, Scott M., Warlick, Christopher A., LeBeau, Aaron M.
Publicado 2018

CK2 Pro-Survival Role in Prostate Cancer Is Mediated via Maintenance and Promotion of Androgen Receptor and NFκB p65 Expression

por Trembley, Janeen H., Kren, Betsy T., Abedin, Md. J., Shaughnessy, Daniel P., Li, Yingming, Dehm, Scott M., Ahmed, Khalil
Publicado 2019

Correction: Exploiting the transcriptional specificity of the alpha-methylacyl-CoA racemase AMACR promoter for the molecular imaging of prostate cancer

por Shapovalova, Mariya, Davydova, Julia, Henzler, Christine, Daniel, Mark, Dehm, Scott M., Warlick, Christopher A., LeBeau, Aaron M.
Publicado 2019

A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities

por Kounatidou, Evangelia, Nakjang, Sirintra, McCracken, Stuart R C, Dehm, Scott M, Robson, Craig N, Jones, Dominic, Gaughan, Luke
Publicado 2019

Targeting chromatin binding regulation of constitutively active AR variants to overcome prostate cancer resistance to endocrine-based therapies

por Chan, Siu Chiu, Selth, Luke A., Li, Yingming, Nyquist, Michael D., Miao, Lu, Bradner, James E., Raj, Ganesh V., Tilley, Wayne D., Dehm, Scott M.
Publicado 2015

AR intragenic deletions linked to androgen receptor splice variant expression and activity in models of prostate cancer progression

por Li, Yingming, Hwang, Tae Hyun, Oseth, LeAnn, Hauge, Adam, Vessella, Robert L., Schmechel, Stephen C., Hirsch, Betsy, Beckman, Kenneth B., Silverstein, Kevin A., Dehm, Scott M.
Publicado 2012

EPI-001 is a selective peroxisome proliferator-activated receptor-gamma modulator with inhibitory effects on androgen receptor expression and activity in prostate cancer

por Brand, Lucas J., Olson, Margaret E., Ravindranathan, Preethi, Guo, Hong, Kempema, Aaron M., Andrews, Timothy E., Chen, Xiaoli, Raj, Ganesh V., Harki, Daniel A., Dehm, Scott M.
Publicado 2015

SV-HotSpot: detection and visualization of hotspots targeted by structural variants associated with gene expression

por Eteleeb, Abdallah M., Quigley, David A., Zhao, Shuang G., Pham, Duy, Yang, Rendong, Dehm, Scott M., Luo, Jingqin, Feng, Felix Y., Dang, Ha X., Maher, Christopher A.
Publicado 2020

Second-Generation Jak2 Inhibitors for Advanced Prostate Cancer: Are We Ready for Clinical Development?

por Beinhoff, Paul, Sabharwal, Lavannya, Udhane, Vindhya, Maranto, Cristina, LaViolette, Peter S., Jacobsohn, Kenneth M., Tsai, Susan, Iczkowski, Kenneth A., Wang, Liang, Hall, William A., Dehm, Scott M., Kilari, Deepak, Nevalainen, Marja T.
Publicado 2021

Computational drug discovery for castration-resistant prostate cancers through in vitro drug response modeling

por Zhang, Weijie, Lee, Adam M., Jena, Sampreeti, Huang, Yingbo, Ho, Yeung, Tietz, Kiel T., Miller, Conor R., Su, Mei-Chi, Mentzer, Joshua, Ling, Alexander L., Li, Yingming, Dehm, Scott M., Huang, R. Stephanie
Publicado 2023

Prognostic association of plasma cell free DNA based androgen receptor amplification and circulating tumor cells in pre-chemotherapy metastatic castration resistant prostate cancer...

por Kohli, Manish, Li, Jian, Du, Meijun, Hillman, David, Dehm, Scott M., Tan, Winston, Carlson, Rachel, Campion, Michael B., Wang, Liguo, Wang, Liewei, Zhang, Huijuan, Zhang, Peng, Kilari, Deepak, Huang, Chiang-Ching, Wang, Liang
Publicado 2018

CK2 targeted RNAi therapeutic delivered via malignant cell-directed tenfibgen nanocapsule: dose and molecular mechanisms of response in xenograft prostate tumors

por Ahmed, Khalil, Kren, Betsy T., Abedin, Md. Joynal, Vogel, Rachel I., Shaughnessy, Daniel P., Nacusi, Lucas, Korman, Vicci L., Li, Yingming, Dehm, Scott M., Zimmerman, Cheryl L., Niehans, Gloria A., Unger, Gretchen M., Trembley, Janeen H.
Publicado 2016

Co-evolution of AR gene copy number and structural complexity in endocrine therapy resistant prostate cancer

por Zivanovic, Andrej, Miller, Jeffrey T, Munro, Sarah A, Knutson, Todd P, Li, Yingming, Passow, Courtney N, Simonaitis, Pijus, Lynch, Molly, Oseth, LeAnn, Zhao, Shuang G, Feng, Felix Y, Wikström, Pernilla, Corey, Eva, Morrissey, Colm, Henzler, Christine, Raphael, Benjamin J, Dehm, Scott M
Publicado 2023

Molecular Profile Changes in Patients with Castrate-Resistant Prostate Cancer Pre- and Post-Abiraterone/Prednisone Treatment

por Sicotte, Hugues, Kalari, Krishna R., Qin, Sisi, Dehm, Scott M., Bhargava, Vipul, Gormley, Michael, Tan, Winston, Sinnwell, Jason P., Hillman, David W., Li, Ying, Vedell, Peter T., Carlson, Rachel E., Bryce, Alan H., Jimenez, Raphael E., Weinshilboum, Richard M., Kohli, Manish, Wang, Liewei
Publicado 2022

ALAN is a computational approach that interprets genomic findings in the context of tumor ecosystems

por Bergom, Hannah E., Shabaneh, Ashraf, Day, Abderrahman, Ali, Atef, Boytim, Ella, Tape, Sydney, Lozada, John R., Shi, Xiaolei, Kerkvliet, Carlos Perez, McSweeney, Sean, Pitzen, Samuel P., Ludwig, Megan, Antonarakis, Emmanuel S., Drake, Justin M., Dehm, Scott M., Ryan, Charles J., Wang, Jinhua, Hwang, Justin
Publicado 2023

Truncation and constitutive activation of the androgen receptor by diverse genomic rearrangements in prostate cancer

por Henzler, Christine, Li, Yingming, Yang, Rendong, McBride, Terri, Ho, Yeung, Sprenger, Cynthia, Liu, Gang, Coleman, Ilsa, Lakely, Bryce, Li, Rui, Ma, Shihong, Landman, Sean R., Kumar, Vipin, Hwang, Tae Hyun, Raj, Ganesh V., Higano, Celestia S., Morrissey, Colm, Nelson, Peter S., Plymate, Stephen R., Dehm, Scott M.
Publicado 2016