Carbamoyl-Phosphate Synthase 1 as a Novel Target of Phomoxanthone A, a Bioactive Fungal Metabolite

por Ceccacci, Sara, Deitersen, Jana, Mozzicafreddo, Matteo, Morretta, Elva, Proksch, Peter, Wesselborg, Sebastian, Stork, Björn, Monti, Maria Chiara
Publicado 2020

Systematic analysis of ATG13 domain requirements for autophagy induction

por Wallot-Hieke, Nora, Verma, Neha, Schlütermann, David, Berleth, Niklas, Deitersen, Jana, Böhler, Philip, Stuhldreier, Fabian, Wu, Wenxian, Seggewiß, Sabine, Peter, Christoph, Gohlke, Holger, Mizushima, Noboru, Stork, Björn
Publicado 2018

Fin56-induced ferroptosis is supported by autophagy-mediated GPX4 degradation and functions synergistically with mTOR inhibition to kill bladder cancer cells

por Sun, Yadong, Berleth, Niklas, Wu, Wenxian, Schlütermann, David, Deitersen, Jana, Stuhldreier, Fabian, Berning, Lena, Friedrich, Annabelle, Akgün, Seda, Mendiburo, María José, Wesselborg, Sebastian, Conrad, Marcus, Berndt, Carsten, Stork, Björn
Publicado 2021

TNF-induced necroptosis initiates early autophagy events via RIPK3-dependent AMPK activation, but inhibits late autophagy

por Wu, Wenxian, Wang, Xiaojing, Sun, Yadong, Berleth, Niklas, Deitersen, Jana, Schlütermann, David, Stuhldreier, Fabian, Wallot-Hieke, Nora, José Mendiburo, María, Cox, Jan, Peter, Christoph, Bergmann, Ann Kathrin, Stork, Björn
Publicado 2021

Prodigiosin Sensitizes Sensitive and Resistant Urothelial Carcinoma Cells to Cisplatin Treatment

por Berning, Lena, Schlütermann, David, Friedrich, Annabelle, Berleth, Niklas, Sun, Yadong, Wu, Wenxian, Mendiburo, María José, Deitersen, Jana, Brass, Hannah U. C., Skowron, Margaretha A., Hoffmann, Michèle J., Niegisch, Günter, Pietruszka, Jörg, Stork, Björn
Publicado 2021

High-throughput screening for natural compound-based autophagy modulators reveals novel chemotherapeutic mode of action for arzanol

por Deitersen, Jana, Berning, Lena, Stuhldreier, Fabian, Ceccacci, Sara, Schlütermann, David, Friedrich, Annabelle, Wu, Wenxian, Sun, Yadong, Böhler, Philip, Berleth, Niklas, Mendiburo, María José, Seggewiß, Sabine, Anand, Ruchika, Reichert, Andreas S., Monti, Maria Chiara, Proksch, Peter, Stork, Björn
Publicado 2021

FIP200 controls the TBK1 activation threshold at SQSTM1/p62-positive condensates

por Schlütermann, David, Berleth, Niklas, Deitersen, Jana, Wallot-Hieke, Nora, Friesen, Olena, Wu, Wenxian, Stuhldreier, Fabian, Sun, Yadong, Berning, Lena, Friedrich, Annabelle, Mendiburo, María José, Peter, Christoph, Wiek, Constanze, Hanenberg, Helmut, Stefanski, Anja, Stühler, Kai, Stork, Björn
Publicado 2021

A systems study reveals concurrent activation of AMPK and mTOR by amino acids

por Pezze, Piero Dalle, Ruf, Stefanie, Sonntag, Annika G., Langelaar-Makkinje, Miriam, Hall, Philip, Heberle, Alexander M., Navas, Patricia Razquin, van Eunen, Karen, Tölle, Regine C., Schwarz, Jennifer J., Wiese, Heike, Warscheid, Bettina, Deitersen, Jana, Stork, Björn, Fäßler, Erik, Schäuble, Sascha, Hahn, Udo, Horvatovich, Peter, Shanley, Daryl P., Thedieck, Kathrin
Publicado 2016

The mycotoxin phomoxanthone A disturbs the form and function of the inner mitochondrial membrane

por Böhler, Philip, Stuhldreier, Fabian, Anand, Ruchika, Kondadi, Arun Kumar, Schlütermann, David, Berleth, Niklas, Deitersen, Jana, Wallot-Hieke, Nora, Wu, Wenxian, Frank, Marian, Niemann, Hendrik, Wesbuer, Elisabeth, Barbian, Andreas, Luyten, Tomas, Parys, Jan B., Weidtkamp-Peters, Stefanie, Borchardt, Andrea, Reichert, Andreas S., Peña-Blanco, Aida, García-Sáez, Ana J., Itskanov, Samuel, van der Bliek, Alexander M., Proksch, Peter, Wesselborg, Sebastian, Stork, Björn
Publicado 2018