Autotaxin Inhibition with IOA-289 Decreases Breast Tumor Growth in Mice Whereas Knockout of Autotaxin in Adipocytes Does Not

por Tang, Xiaoyun, Morris, Andrew J., Deken, Marcel A., Brindley, David N.
Publicado 2023

Non-Clinical Toxicology Evaluation of the Novel Non-ATP Competitive Oral PI3 Kinase Delta Inhibitor Roginolisib

por van der Veen, Lars, Schmitt, Michael, Deken, Marcel A., Lahn, Michael
Publicado 2023

Synchronous BRAF(V600E) and MEK inhibition leads to superior control of murine melanoma by limiting MEK inhibitor induced skin toxicity

por Gadiot, Jules, Hooijkaas, Anna I, Deken, Marcel A, Blank, Christian U
Publicado 2013

Dermal Delivery of Constructs Encoding Cre Recombinase to Induce Skin Tumors in Pten(LoxP/LoxP);Braf(CA/+) Mice

por Deken, Marcel A., Song, Ji-Ying, Gadiot, Jules, Bins, Adriaan D., Kroon, Paula, Verbrugge, Inge, Blank, Christian U.
Publicado 2016

Concomitant targeting of programmed death-1 (PD-1) and CD137 improves the efficacy of radiotherapy in a mouse model of human BRAFV600-mutant melanoma

por Kroon, Paula, Gadiot, Jules, Peeters, Marlies, Gasparini, Alessia, Deken, Marcel A., Yagita, Hideo, Verheij, Marcel, Borst, Jannie, Blank, Christian U., Verbrugge, Inge
Publicado 2016

Targeting the MAPK and PI3K pathways in combination with PD1 blockade in melanoma

por Deken, Marcel A., Gadiot, Jules, Jordanova, Ekaterina S., Lacroix, Ruben, van Gool, Melissa, Kroon, Paula, Pineda, Cristina, Geukes Foppen, Marnix H., Scolyer, Richard, Song, Ji-Ying, Verbrugge, Inge, Hoeller, Christoph, Dummer, Reinhard, Haanen, John B. A. G., Long, Georgina V., Blank, Christian U.
Publicado 2016