The Ubiquitin Proteasome System in Hematological Malignancies: New Insight into Its Functional Role and Therapeutic Options

por Di Costanzo, Antonella, Del Gaudio, Nunzio, Conte, Lidio, Altucci, Lucia
Publicado 2020

KDM4 Involvement in Breast Cancer and Possible Therapeutic Approaches

por Varghese, Benluvankar, Del Gaudio, Nunzio, Cobellis, Gilda, Altucci, Lucia, Nebbioso, Angela
Publicado 2021

Unexpected and durable response with regorafenib in a metastatic colorectal cancer patient without KDR mutation: A case report

por Rosati, Gerardo, Del Gaudio, Nunzio, Scarano, Enrico, Cifarelli, Rosa Anna, Altucci, Lucia, Bilancia, Domenico
Publicado 2018

HDAC6 Inhibition Extinguishes Autophagy in Cancer: Recent Insights

por Passaro, Eugenia, Papulino, Chiara, Chianese, Ugo, Toraldo, Antonella, Congi, Raffaella, Del Gaudio, Nunzio, Nicoletti, Maria Maddalena, Benedetti, Rosaria, Altucci, Lucia
Publicado 2021

The HDAC inhibitor SAHA regulates CBX2 stability via a SUMO-triggered ubiquitin-mediated pathway in leukemia

por Di Costanzo, Antonella, Del Gaudio, Nunzio, Conte, Lidio, Dell’Aversana, Carmela, Vermeulen, Michiel, de Thé, Hugues, Migliaccio, Antimo, Nebbioso, Angela, Altucci, Lucia
Publicado 2018

Discovery of a new class of triazole based inhibitors of acetyl transferase KAT2A

por Pacifico, Roberta, Del Gaudio, Nunzio, Bove, Guglielmo, Altucci, Lucia, Siragusa, Lydia, Cruciani, Gabriele, Ruvo, Menotti, Bellavita, Rosa, Grieco, Paolo, Adamo, Mauro F. A.
Publicado 2022

Metabolic Pathways as a Novel Landscape in Pancreatic Ductal Adenocarcinoma

por Ali, Ahmad, Chianese, Ugo, Papulino, Chiara, Toraldo, Antonella, Abakar, Mawada Elmagboul Abdalla, Passaro, Eugenia, Cennamo, Rosario, Del Gaudio, Nunzio, Altucci, Lucia, Benedetti, Rosaria
Publicado 2022

Looking Beyond the Glioblastoma Mask: Is Genomics the Right Path?

por Montella, Liliana, Del Gaudio, Nunzio, Bove, Guglielmo, Cuomo, Mariella, Buonaiuto, Michela, Costabile, Davide, Visconti, Roberta, Facchini, Gaetano, Altucci, Lucia, Chiariotti, Lorenzo, Della Monica, Rosa
Publicado 2022

BRD9 binds cell type-specific chromatin regions regulating leukemic cell survival via STAT5 inhibition

por Del Gaudio, Nunzio, Di Costanzo, Antonella, Liu, Ning Qing, Conte, Lidio, Migliaccio, Antimo, Vermeulen, Michiel, Martens, Joost H. A., Stunnenberg, Hendrik G., Nebbioso, Angela, Altucci, Lucia
Publicado 2019

Histone Deacetylase Inhibitors Impair Vasculogenic Mimicry from Glioblastoma Cells

por Pastorino, Olga, Gentile, Maria Teresa, Mancini, Alessandro, Del Gaudio, Nunzio, Di Costanzo, Antonella, Bajetto, Adriana, Franco, Paola, Altucci, Lucia, Florio, Tullio, Stoppelli, Maria Patrizia, Colucci-D’Amato, Luca
Publicado 2019

Longitudinal single-cell transcriptomics reveals distinct patterns of recurrence in acute myeloid leukemia

por Zhai, Yanan, Singh, Prashant, Dolnik, Anna, Brazda, Peter, Atlasy, Nader, del Gaudio, Nunzio, Döhner, Konstanze, Döhner, Hartmut, Minucci, Saverio, Martens, Joost, Altucci, Lucia, Megchelenbrink, Wout, Bullinger, Lars, Stunnenberg, Hendrik G.
Publicado 2022

CBX2 shapes chromatin accessibility promoting AML via p38 MAPK signaling pathway

por Del Gaudio, Nunzio, Di Costanzo, Antonella, Liu, Ning Qing, Conte, Lidio, Dell’Aversana, Carmela, Bove, Guglielmo, Benedetti, Rosaria, Montella, Liliana, Ciardiello, Fortunato, Carafa, Vincenzo, Ambrosino, Concetta, Tucci, Valeria, Conte, Mariarosaria, Martens, Joost H. A., Stunnenberg, Hendrik G., Nebbioso, Angela, Altucci, Lucia
Publicado 2022

Histone lysine demethylase inhibition reprograms prostate cancer metabolism and mechanics

por Chianese, Ugo, Papulino, Chiara, Passaro, Eugenia, Evers, Tom MJ., Babaei, Mehrad, Toraldo, Antonella, De Marchi, Tommaso, Niméus, Emma, Carafa, Vincenzo, Nicoletti, Maria Maddalena, Del Gaudio, Nunzio, Iaccarino, Nunzia, Randazzo, Antonio, Rotili, Dante, Mai, Antonello, Cappabianca, Salvatore, Mashaghi, Alireza, Ciardiello, Fortunato, Altucci, Lucia, Benedetti, Rosaria
Publicado 2022